CD62L is expressed on neutrophils, monocytes, T- and B-lymphocyte subsets and NK cells. BD Horizon™ BV480 Mouse Anti-Human CD62L DREG-56 antibody recognizes the same antigen as LAM-1, and specifically inhibits >90% of binding of human lymphocytes to high endothelial venules (HEV) in frozensections of peripheral, but not mucosal lymphoid tissue.