Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

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4,576 – 4,590 of 60,538 results

4,576

Cayman Chemical Evernic Acid, Purity: ≥98%, CAS: 537-09-7, 5 mg

A secondary metabolite produced by some species of lichen that binds FAS-II enzymes to produce antibacterial and antiplasmodial effects; inhibits PfFabZ and PfFabI (IC50 = 10.7 and 36.1 µM, respectively) but shows low efficacy against the malaria parasite P. berghei (IC50 = 77.3 µM)

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4,577

Medchemexpress LLC Remibrutinib | 1787294-07-8 | 99.8% | 100 MG

Remibrutinib is a potent and orally active Bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. It inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib has potential for Chronic Urticaria (CU) treatment. This product is for research use only and not sold to patients.

Potent and orally active Bruton tyrosine kinase (BTK) inhibitor
Inhibits BTK enzymatic activity with an IC50 value of 1 nM
Inhibits BTK activity in blood with an IC50 value of 0.023 μM
Potential for Chronic Urticaria (CU) treatment
Molecular weight: 507.53
Chemical formula: C27H27F2N5O3
Appearance: white to off-white solid

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4,578

Cayman Chemical D-64131, Purity: ≥98%, CAS: 74588-78-6, 10 mg

An inhibitor of tubulin polymerization (IC50 = 0.53 µM); arrests the cell cycle at the G2/M transition (IC50 = 92 nM); preferentially cytotoxic to cycling cells; has antiproliferative activity in various cancer cell lines (IC50s = 24-144 nM) and in cell lines resistant to other tubulin inhibitors (IC50s = 20-77 nM); reduces tumor growth in a mouse xenograft model of human amelanoic melanoma at doses of 200 and 400 mg/kg

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4,579

Medchemexpress LLC Cyanidin-3-O-arabinoside | 111613-04-8 | 95.7% | 1 MG

Cyanidin-3-O-arabinoside is an antioxidant agent and a pigment isolated from flowers of *Rhododendron cv. Lems Stormcloud*. It is for research use only.

Antioxidant agent
Pigment isolated from flowers of Rhododendron cv. Lems Stormcloud
For research use only
Purity of 95.71%
Solid appearance
Brown to black color
Store at -20°C in sealed container, away from moisture and light
In solvent, store at -80°C for 6 months, or -20°C for 1 month in sealed container, away from moisture and light

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4,580

Sigma Aldrich Fine Chemicals Biosciences Thymine suitable for cell culture, BioReagent | 65-71-4 | MFCD00006026 | 5G

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4,581

Medchemexpress LLC Procaine | 59-46-1 | 99.79% | 5 G

Procaine is a DNA-demethylating agent that works through multiple targets, characterized by a slow onset and short duration of action. It inhibits 5-HT3 receptor-mediated inward current and reduces 5-methylcytosine DNA content by 40%. Additionally, Procaine exhibits growth-inhibitory effects in cancer cells and acts as an excitant of limbic system cells, altering synaptic transmission.

Inhibits 5-HT3 receptor-mediated inward current
Reduces 5-methylcytosine DNA content
Demethylates densely hypermethylated CpG islands
Exhibits growth-inhibitory effects in cancer cells
Induces mitotic arrest
Acts as an excitant of limbic system cells
Alters synaptic transmission from the amygdala

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4,582

Medchemexpress LLC Ebsulfur | 2527-03-9 | 99.4% | 50 MG

Ebsulfur is a benzisothiazolone cytocidal inhibitor that targets the trypanothione reductase (TryR) of *Trypanosoma brucei*. It is used for research on African trypanosomiasis.

Targets trypanothione reductase (TryR) of *Trypanosoma brucei*
Has IC50 values of 61-293 nM for *Trypanosoma brucei*
Used for research on African trypanosomiasis

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4,583

Cayman Chemical T-1095, Purity: ≥98%, CAS: 209746-59-8, 10 mg

An SGLT1 and SGLT2 inhibitor (IC50s = 22.8 and 2.3 µM, respectively); dietary administration reduces blood glucose and HbA1c levels in a rat model of streptozotocin-induced diabetes at 0.01% w/w; suppresses the development of hyperglycemia and hypertriglyceridemia and reduces HbA1c levels in the KKAγ mouse model of type 2 diabetes; exacerbates post-infarction cardiac dysfunction in a rat model of left anterior descending coronary artery ligation-induced myocardial infarction

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4,584

Cayman Chemical FDU-PB-22, Purity: ≥98%, CAS: 1883284-94-3, 10 mg

An analytical reference standard categorized as a synthetic cannabinoid; has been found in samples seized by law enforcement; intended for research and forensic applications

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4,585

Selleck Chemical LLC Compound E S0058-5MG

Compound E ( -Secretase-IN-1) is a potent inhibitor of -secretase which blocks -secretase-mediated cleavage of Notch with an IC50 of 0 32 nM It also suppresses the production of -amyloid(40) and -amyloid(42) with IC50 values of 0 24 nM and 0 37 nM respectively It also inhibits Notch signalling significantly disrupting gonadotropin-dependent follicle growth and halting progression to the preovulatory stage of development

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4,586

Medchemexpress LLC Nabumetone | 42924-53-8 | 99.9% | 1 ML

Nabumetone is an orally active non-acidic anti-inflammatory agent, acting as a potent and selective COX-2 inhibitor, and is the proagent of the active metabolite α-Demethylnaproxen. It can inhibit cancer cell proliferation and relieve gastric ulcers.

Orally active non-acidic anti-inflammatory agent
Potent and selective COX-2 inhibitor
Proagent of the active metabolite α-Demethylnaproxen
Inhibits cancer cell proliferation
Relieves gastric ulcers

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4,587

Cayman Chemical 8(Z)-Eicosenoic Acid methyl ester, Purity: ≥95%, CAS: 69119-99-9, 5 mg

An esterified form of 8(Z)-eicosenoic acid; has been used as a standard for the quantification of 8(Z)-eicosenoic acid by gas chromatography

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4,588

Medchemexpress LLC Procaine hydrochloride | 51-05-8 | 97.9% | 10 G

Procaine hydrochloride is a DNA-demethylating agent that acts through multiple targets and has a slow onset and a short duration of action. It is for research use only and not sold to patients. It functions as an excitant of limbic system cells and alters synaptic transmission in certain output pathways from the amygdale.

Inhibits the 5-HT3 receptor-mediated inward current.
Reduces 5-methylcytosine DNA content by 40%.
Demethylates densely hypermethylated CpG islands.
Exhibits growth-inhibitory effects in cancer cells, causing mitotic arrest.

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4,589

AdipoGen Creatine . monohydrate (5 g)

Chemical. CAS: 6020-87-7. Formula: C4H9N3O2 . H2O. MW: 131.1 . 18.0. Synthetic. A nitrogenous organic acid that occurs naturally in vertebrates. Can be acquired through dietary consumption or formed from L-arginine, glycine and L-methionine in a multi-step reaction that occurs in the kidney and liver. High-energy reservoir for the rapid regeneration of ATP. Its main role is to facilitate recycling of adenosine triphosphate (ATP) primarily in muscle and brain tissue via the action of creatine kinase(s). Supplementation is investigated for the use in myopathies and enhancement of sports performance, primarily by increasing muscle mass. It is also investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state. Antioxidant compound. Thermogenesis enhancer in beige adipocytes. Creatine cycling is important for thermogenesis and an altered creatine cycle could lead to obesity.

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4,590

Medchemexpress LLC 2-Chloroacetamide | 79-07-2 | 99.9% | 93.51 | 10 G

2-Chloroacetamide is a chemical compound that serves as a preservative and herbicide for both uplands and paddy fields. It is also used as a biocide in agriculture, glues, paints, and coatings. This compound is known for its ability to inhibit very-long-chain fatty acid elongase.

Functions as a preservative
Functions as a herbicide
Acts as a biocide in agriculture, glues, paints, and coatings
Inhibits very-long-chain fatty acid elongase
Demonstrates herbicidal activities against paddy field weeds

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Bioactive Small Molecules

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Medchemexpress LLC Remibrutinib | 1787294-07-8 | 99.8% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Cyanidin-3-O-arabinoside | 111613-04-8 | 95.7% | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Procaine | 59-46-1 | 99.79% | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ebsulfur | 2527-03-9 | 99.4% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nabumetone | 42924-53-8 | 99.9% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Procaine hydrochloride | 51-05-8 | 97.9% | 10 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2-Chloroacetamide | 79-07-2 | 99.9% | 93.51 | 10 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More