Bioactive Small Molecules
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Filtered Search Results
Chemscene ChemScene | 2-Amino-2-(p-tolyl)acetic acid | 5G | CS-W006187 | 0.97 | 13227-01-5| MFCD00665357 | 165.19
ChemScene | 2-Amino-2-(p-tolyl)acetic acid | 5G | CS-W006187 | 0.97 | 13227-01-5| MFCD00665357 | 165.19
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Medchemexpress LLC Fusidic acid sodium salt | 751-94-0 | 99.6% | 5 G
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Fusidic acid sodium salt is an orally available antibacterial agent that inhibits bacterial protein synthesis. It also exhibits antidiabetic effects in a rat model and improves colitis symptoms in rats.
- Inhibits bacterial protein synthesis by preventing the release of translation elongation factor G (EF-G) from ribosomes.
- Exhibits antidiabetic effects by inhibiting the effects of interleukins IL-1 and IL-6 on glucose-induced insulin production.
- Improves colitis symptoms.
- Inhibits the growth of *Toxoplasma gondii* and *Listeria monocytogenes* EGD in vitro.
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Cayman Chemical IMR-1, Purity: ≥95% (mixture of isomers), CAS: 310456-65-6, 5 mg
An inhibitor of Maml1 recruitment to chromatin; binds to the intracellular domain of Notch (KD = 11 µM) and prevents transcription of Notch target genes by inhibiting the recruitment of Maml1 to chromatin; inhibits colony formation in Notch-dependent cell lines but not Notch-independent cell lines at 15 and 45 µM; decreases the expression of Notch target genes and reduces tumor growth in a patient-derived esophageal adenocarcinoma mouse xenograft model at 15 mg/kg
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eMolecules 426834-69-7 | Medchem Express | NS5806 | 5mg | 495799674 | HY-108588 | 574.079 | C16H8Br2F6N6O
Ambeed | (11bR)-111-Trifluoro-N-(4-oxido-26-di(phenanthren-9-yl)dinaphtho[21-d12-f][132]dioxaphosphepin-4-yl)methanesulfonamide | 50mg | 633658938 | A1006066 | 937028-51-8 | 831.800 | C49H29F3NO5PS
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eMolecules Building Block Tool
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Medchemexpress LLC Dfdbi-2T | 1539318-40-5 | 98.0% | 306.19 | 1 ML
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DFHBI-2T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=500 nm/523 nm). It is used to image RNA in live cells.
- For research use only.
- Not independently confirmed for accuracy of methods.
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Medchemexpress LLC 2-Fluorophenol | 367-12-4 | 99.8% | 112.10 | 500 G
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2-Fluorophenol is a biochemical reagent that serves as a versatile biological material or organic compound for various life science-related research applications.
- Functions as a biochemical reagent.
- Can be utilized as a biological material.
- Serves as an organic compound for research.
- Aids in life science investigations.
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Medchemexpress LLC Thieno[2,3-c]pyridine-6(5H)-carboxamide, 3-cyano-4,7-dihydro-N-(2-methoxyphenyl)-2-[[(1-methyl-1H-pyrazol-4-yl)carbonyl]amino]- | 2248552-84-1 | 99.9% | 436.49 | 1 ML
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WB436B is a highly selective STAT3 inhibitor that can selectively inhibit STAT3-Tyr705 phosphorylation and the expression of STAT3 target genes. It shows cytotoxic effects on pancreatic cancer cells, induces apoptosis, and can suppress tumor growth and metastasis in pancreatic cancer mouse models, extending the survival of tumor-bearing mice.
- Selectively inhibits STAT3-Tyr705 phosphorylation
- Suppresses expression of STAT3 target genes
- Induces apoptosis in pancreatic cancer cells
- Suppresses tumor growth and metastasis in pancreatic cancer mouse models
- Extends survival in tumor-bearing mice
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Cayman Chemical ZZL-7, Purity: ≥95%, CAS: 99141-91-0, 50 mg
A SERT-nNOS protein-protein interaction inhibitor; increases in vivo serotonergic neuron firing diminished by decreased SERT levels in SERT-Cre transgenic mice, which have reduced SERT levels, at 10 mg/kg; reduces immobility time in the tail suspension test and forced swim test in mice at 20 and 40 mg/kg
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TARGETMOL CHEMICALS INC LEM-14 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. LEM-14 is a potent NSD2-specific inhibitor (IC50132 uM).LEM-14 may be used in the study of multiple myeloma. purity: 98%
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Cayman Chemical JNJ-42756493, Purity: ≥98%, CAS: 1346242-81-6, 5 mg
A pan-FGFR inhibitor (IC50s = 1.2, 2.5, 3, and 5.7 nM for FGFR1, -2, -3, and -4, respectively); selective for FGFRs over VEGFR2 (IC50 = 36.8 nM); inhibits the proliferation of Ba/F3 cells expressing FGFR1, 3, or 4 (IC50s = 22.1, 13.2, and 25 nM, respectively); reduces tumor growth in a SNU-16 gastric cancer mouse xenograft model at 10 and 30 mg/kg
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Medchemexpress LLC Seladelpar (lysine) | 928821-41-4 | 98.0 % | 590.65 | 5 MG
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Seladelpar lysine is an orally active, potent, and specific PPARδ agonist with an EC50 of 2 nM. It exhibits more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar lysine can be used for the study of primary biliary cholangitis.
- Orally active, potent, and specific PPARδ agonist
- High selectivity over PPARα and PPARγ receptors (>750-fold and >2500-fold, respectively)
- Can be used for the study of primary biliary cholangitis
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Cayman Chemical (−)-Catechin, Purity: ≥98%, CAS: 18829-70-4, 5 mg
A diastereoisomer of catechin having a trans 2S,3R configuration at the chiral center; a potent antioxidant that inhibits the free radical-induced oxidation of isolated LDL by AAPH
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Medchemexpress LLC CD96 Human HEK293 50ug
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CD96 promotes adhesive interactions between activated T cells and NK cells in the late stages of the immune response It promotes the adhesion between NK cells and target cells by interacting with PVR on target cells CD96 Protein Human (HEK293 His) is the recombinant human-derived CD96 protein expressed by HEK293 with C-6 His labeled tag
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Cayman Chemical STO-609, Purity: ≥95% (mixture of isomers), CAS: 52029-86-4, 1 mg
A CaMKK inhibitor (IC50s = 120 and 40 ng/ml for CaMKKα and CaMKKβ, respectively); selective for CaMKKs over CaMKI, CaMKII, CaMKIV, MLCK, PKC, PKA, and p42 MAPK (IC50s = ≥ 10,000 ng/ml for all); inhibits phosphorylation of CaMKI and AMPK in chicken sperm in the presence of extracellular calcium, as well as reduces chicken sperm motility; decreases Npy and Agrp expression and cumulative food intake in mice at 20 μM 0.5 μL/hour, i.c.v.; increases cortical, striatal, and total infarct volume in a mouse model of MCAO-induced focal transient cerebral ischemia at 3 μg/animal, i.c.v.
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Medchemexpress LLC Atn-161 | 262438-43-7 | 99.4% | C23H35N9O8S | 10MG
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ATN-161 is a novel integrin α5β1 antagonist peptide that inhibits angiogenesis and the growth of liver metastases in murine models. Supplied as a white to off-white solid for research use only, it has high chemical purity and defined storage and solubility properties suited for in vitro and in vivo experimental applications.
- High purity suitable for research applications.
- Peptide antagonist of integrin α5β1 with anti-angiogenic activity in vivo.
- Available as a stable solid with recommended low-temperature storage.
- Soluble in DMSO and water to facilitate assay preparation.
- Intended for laboratory research use only; not for human use.
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