Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

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6,076 – 6,090 of 60,541 results

6,076

Cayman Chemical SureLIghtPE-695 5mg

A highly potent reversible inhibitor of the EGFR (Ki 5.2 pM IC50 29 pM) rapidly suppresses autophosphorylation of EGFR in ﬁbroblasts and human epidermoid carcinoma cells

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6,077

Cayman Chemical LY2801653, Purity: ≥98%, CAS: 1206799-15-6, 50 mg

A MET kinase inhibitor (Ki = 2 nM); inhibits MST1R, Axl, MNK1/2, FLT3, DDR1, and DDR2 (IC50s = 11, 2, 7, 7, 0.1, and 7 nM, respectively); inhibits HGF-induced MET autophosphorylation in H460 and S114 cells (IC50s = 35.2 and 59.2 nM, respectively) and inhibits growth of Ba/F3 cells transfected with MET-activating mutations (IC50s = 12-248 nM); completely blocks cell scattering induced by HGF in DU145 cells at 0.01-10 µM; reduces tumor growth in MET autocrine (U-87MG) and MET over-expression (H441) mouse xenograft models at 4 and 12 mg/kg

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6,078

Cayman Chemical TX-1918, Purity: ≥98%, CAS: 503473-32-3, 1 mg

A selective eEF-2K inhibitor (IC50 = 440 nM); disrupts the proliferation of HepG2 and HCT116 tumor cells (EC50s = 2.07 and 230 µM, respectively) with low mitochondrial toxicity

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6,079

Selleck Chemical LLC Hovenia Dulcis Fruit Extract E3872-5MG

Hovenia Dulcis Fruit Extract is extracted from the fruits of Hovenia dulcis which has functions such as liver protection and detoxification from alcohol poisoning

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6,080

Medchemexpress LLC 2-[1-(4-chloro-phenyl)-cyclopropyl]-7-iodo-5-oxo-4,5-dihydro-pyrazolo[1,5-a]quinazoline-3-carbonitrile | 2226517-75-3 | 98.2% | C20H12ClIN4O | 10MG

Dynapyrazole-A is a selective small-molecule inhibitor that targets the ATPase activity of microtubule-stimulated dynamin, used in biochemical and cellular studies to probe dynamin-dependent membrane trafficking and endocytosis processes.

Selective inhibitor of microtubule-stimulated dynamin ATPase activity.
High purity 98.2% suitable for research assays.
Soluble in DMSO (25 mg/mL); available as 10 mM solution in DMSO.
Stable as powder at -20°C for extended storage; store solutions at -80°C for best stability.
Suitable for biochemical and cell biology studies involving dynamin-dependent processes.

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6,081

Medchemexpress LLC HY-N7378 5mg Medchemexpress, N-Hydroxypipecolic acid CAS:115819-92-6 Purity:>98%

Medchemexpress, HY-N7378 5mg N-Hydroxypipecolic acid CAS:115819-92-6 N-Hydroxypipecolic acid (1-Hydroxy-2-piperidinecarboxylic acid), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxypipecolic acid accumulates systemically in the plant foliage in response to pathogen attack. N-Hydroxypipecolic acid induces SAR to bacterial and oomycete infection[2][3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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6,082

Medchemexpress LLC Nylidrin hydrochloride | 849-55-8 | 98.7% | 5 MG

Nylidrin hydrochloride, also known as Buphenine hydrochloride, is an orally active β-adrenergic agonist. This compound demonstrates significant biological activity, including antagonism of NR1A/2B NMDA receptors, reduction of NP, HA, and M1 levels, and antiviral efficacy against H1N1 influenza A viruses. It also shows promise in improving hemorrhagic shock and exhibiting anti-allergic effects.

Orally active β-adrenergic agonist
Antagonizes NR1A/2B NMDA receptors (IC50 = 0.18 μM in Xenopus oocytes)
Reduces levels of NP, HA, and M1
Demonstrates antiviral activity against multiple H1N1 subtype influenza A viruses
Improves hemorrhagic shock
Possesses anti-allergic effects

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6,083

eMolecules 108068-98-0 | KT5720 | Apollo Scientific537.616 | C32H31N3O5 | 0.000 | CCCCCCOC(=O)[C@]1(O)C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 | 1mg | 562467307

KT5720 | Apollo Scientific | 108068-98-0537.616 | C32H31N3O5 | 0.000 | CCCCCCOC(=O)[C@]1(O)C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 | 1mg | 562467307

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6,084

Selleck Chemical LLC 2-C-Methylcytidine E6045-25MG

2 -C-Methylcytidine (NM107) is a potent and selective inhibitor of Chronic hepatitis C virus (HCV) NS5B polymerase with an EC50 of 1 85 M in wild-type replicon cells It also effectively inhibits foot-and-mouth disease virus(FMDV) replication with an EC50 of 6 4 M Therefore it is a potent antiviral that targets both viral and host factors making it a promising option for HCV therapy and a potential prophylactic or therapeutic agent against FMDV outbreaks

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6,085

Medchemexpress LLC Integrin beta 4 Antibody (YA3280) | 50 UL

Integrin beta 4 Antibody (YA3280) is an unconjugated IgG antibody (clone number: YA3280) that specifically targets Integrin beta 4. This antibody is suitable for Western Blot (WB) and Immunohistochemistry-Paraffin (IHC-P) applications, showing reactivity in both human and mouse samples. It has an observed molecular weight of 210 kDa.

Host: Rabbit
Clonality: Recombinant, monoclonal
Conjugate: Non-conjugated
Applications: Western blot (WB), immunohistochemistry-paraffin (IHC-P)
Species reactivity: Human, mouse
Isotype: IgG
Synonyms: CD104, gp150, Integrin beta 4 subunit, ITG B4, ITGB 4, Itgb4
Purification method: Affinity chromatography
Storage conditions: Store at -20°C for 1 year. Avoid repeated freeze/thaw cycles. Shipped with blue ice.
Purity: ≥98.0%

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6,086

Medchemexpress LLC (S)-WSD0628 | 2765449-10-1 | 99.8% | 439.46 | 25 MG

(S)-WSD0628 (Compound 28) is the S-isomer of WSD0628. It is an inhibitor for ATM that inhibits the phosphorylation of ATM in MCF-7 cells with an IC50 <100 nM. (S)-WSD0628 exhibits radiosensitizing activity and can cross the blood-brain barrier.

ATM inhibitor
Inhibits phosphorylation of ATM in MCF-7 cells with IC50 <100 nM
Exhibits radiosensitizing activity
Can cross the blood-brain barrier

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6,087

Cayman Chemical 1,3-Dilignoceroyl Glycerol, Purity: ≥98%, CAS: 120639-92-1, 5 mg

A diacylglycerol

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6,088

Cayman Chemical AFN-1252, Purity: ≥98%, CAS: 620175-39-5, 10 mg

An inhibitor of staphylococcal FabI (Ki = 12.8 nM); selective for isolates of methicillin-susceptible and methicillin-resistant S. aureus (MIC90s = ≤0.008 μg/ml) over isolates of S. pneumoniae, β-hemolytic streptococci, Enterococcus, Enterobacteriaceae, non-fermentative Gram-negative bacilli, and M. catarrhalis (MIC90s = >4 μg/ml); increases survival in a murine acute lethal septicemia model at 1 mg/kg

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6,089

Cayman Chemical 11-oxo MGV, Purity: ≥95%, CAS: 126105-11-1, 1 mg

A sweet tasting cucurbitane glycoside antioxidant (EC50s = 4.79 and 16.52 µg/ml against O2- and OH-, respectively); inhibits carcinogenesis in murine models

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6,090

Cayman Chemical BI-1467335, Purity: ≥95%, CAS: 1478364-68-9, 25 mg

An inhibitor of VAP-1 (IC50 = 50s = >1,000 and >10,000 nM, respectively); reduces plasma total cholesterol, LDL, and glucose levels, as well as decreases the recruitment of macrophages to atherosclerotic lesions and the area of atherosclerotic plaques, in a cholesterol-fed rabbit model at 10 mg/kg per day; reduces K. pneumoniae-induced neutrophil lung infiltration in mice at 6 mg/kg; reduces airway hyperreactivity in a mouse model of rhinovirus-exacerbated allergy-induced asthma

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Bioactive Small Molecules

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Medchemexpress LLC 2-[1-(4-chloro-phenyl)-cyclopropyl]-7-iodo-5-oxo-4,5-dihydro-pyrazolo[1,5-a]quinazoline-3-carbonitrile | 2226517-75-3 | 98.2% | C20H12ClIN4O | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-N7378 5mg Medchemexpress, N-Hydroxypipecolic acid CAS:115819-92-6 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nylidrin hydrochloride | 849-55-8 | 98.7% | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Integrin beta 4 Antibody (YA3280) | 50 UL Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (S)-WSD0628 | 2765449-10-1 | 99.8% | 439.46 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2-[1-(4-chloro-phenyl)-cyclopropyl]-7-iodo-5-oxo-4,5-dihydro-pyrazolo[1,5-a]quinazoline-3-carbonitrile | 2226517-75-3 | 98.2% | C20H12ClIN4O | 10MG

Medchemexpress LLC HY-N7378 5mg Medchemexpress, N-Hydroxypipecolic acid CAS:115819-92-6 Purity:>98%

Medchemexpress LLC Nylidrin hydrochloride | 849-55-8 | 98.7% | 5 MG

Medchemexpress LLC Integrin beta 4 Antibody (YA3280) | 50 UL

Medchemexpress LLC (S)-WSD0628 | 2765449-10-1 | 99.8% | 439.46 | 25 MG