Bioactive Small Molecules
Medchemexpress LLC HY-N6789 50ug Medchemexpress, KT5720 CAS:108068-98-0 Purity:>98%
Medchemexpress, HY-N6789 50ug KT5720 CAS:108068-98-0 KT5720 is a cell-permeable, potent, specific, reversible, ATP-competitive inhibitor of protein kinase A (PKA), with a Ki of 60 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Eurofins Discoverx Forskolin, 2 x 0.25 mg. (92-0005)
Forskolin is a labdane diterpene produced by the Indian Coleus plant, Coleus forskohlii. It is commonly used to raise levels of cyclic AMP (cAMP) associated with the study of cell physiology mechanisms. It acts by activating the enzyme adenyl cyclase to increase intracellular levels of this second messenger, which is necessary for the proper biological response of cells to hormones and other extracellular signals. Provided as 2 vials of 0.25 mg dry powder each. These highly purified, pre-validated control ligands have been used to qualify our InCELL Hunter, PathHunter and cAMP Hunter cell lines as well as our Assay Ready Kits. Ligands are conveniently supplied with a recommended reconstitution buffer. For detailed information and product-specific datasheet, visit www.discoverx.com/ligands.
Medchemexpress LLC HY-W026772 500mg Medchemexpress, Fluorene CAS:86-73-7 Purity:>98%
Medchemexpress, HY-W026772 500mg Fluorene CAS:86-73-7 Fluorene, a polycyclic aromatic hydrocarbon (PAH), is a precursor to other fluorene compounds. Fluorene and its derivative can be used as a precursor to pharmaceuticals or fluorene-based dyes. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-108841 50mg , Raleukin CAS:143090-92-0 Purity:>98%
HY-108841 50mg Raleukin CAS: 143090-92-0 Raleukin (AMG-719) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Raleukin (AMG-719) is the first biological agent to block the pro-inflammatory effects. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-12481 10mg , SAR405 CAS:1523406-39-4 Purity:>98%
HY-12481 10mg SAR405 CAS: 1523406-39-4 SAR405 is a first-in-class, selective, and ATP-competitive PI3K class III (PIK3C3) isoform Vps34 inhibitor (IC50=1.2 nM; Kd=1.5 nM). SAR405 inhibits autophagy induced either by starvation or by mTOR inhibition. Anticancer activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-127105 10mg , Iptacopan CAS:1644670-37-0 Purity:>98%
HY-127105 10mg Iptacopan CAS: 1644670-37-0 Iptacopan (LNP023) is a first-in-class, orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 value of 10 nM. Iptacopan shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM. Iptacopan targets the underlying cause of complement 3 glomerulopathy (C3G). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-W040193 500mg , 1,2-Distearoyl-sn-glycero-3-phosphorylcholine CAS:816-94-4 Purity:>98%
HY-W040193 500mg 1,2-Distearoyl-sn-glycero-3-phosphorylcholine CAS: 816-94-4 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-10162 100mg , Olaparib CAS:763113-22-0 Purity:>98%
HY-10162 100mg Olaparib CAS: 763113-22-0 Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator[4]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-12885A 1mg , ADU-S100 (disodium salt) CAS:1638750-95-4 Purity:>98%
HY-12885A 1mg ADU-S100 (disodium salt) CAS: 1638750-95-4 ADU-S100 disodium salt (MIW815 disodium salt) is an activator of stimulator of interferon genes (STING). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-17359 25mg , Deferasirox CAS:201530-41-8 Purity:>98%
HY-17359 25mg Deferasirox CAS: 201530-41-8 Deferasirox (ICL 670) is an orally available iron chelator used for the management of transfusional iron overload. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-132167 5mg , AZD5305 CAS:2589531-76-8 Purity:>98%
HY-132167 5mg AZD5305 CAS: 2589531-76-8 AZD5305 is a potent, selective and oral active PARP inhibitor. AZD5305 is potent and efficacious in animal xenografts and PDX models. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
STEMCELL Technologies PD173074, Size: 10 mg
Inhibit FGFR and suppress the differentiation of mouse embryonic stem (ES) cells with PD173074 (Kunath et al. Development, 2007, Ying et al. Nature, 2008). PD173074 is used to block neural differentiation of mouse ES cells (Stavridis et al. Development, 2007); promoting differentiation of human ES cells, but not when they are in a naïve or "ground" state (Hanna et al. Proc Natl Acad Sci USA, 2010); and to prevent excision-mediated differentiation of mouse induced pluripotent stem cells generated using piggyBac transposons (Kaji et al. Nature, 2009). In combination with other small molecules, PD173074 is also used to reprogram human ES cells to naïve cells or maintain human ES cells in their naïve state (Hanna et al. Proc Natl Acad Sci USA, 2010). PD173074 is supplied as a crystalline solid with ≥98% purity; Molecular weight 523.7 g/mol; CAS Number 219580-11-7. Visit STEMCELL.com for more information and related products.
Selleck Chemical LLC SEL120 S8840-25MG
SEL120 (SEL120-34 SEL120-34A) is a novel inhibitor of Cyclin-dependent kinase 8 (CDK8) with IC50 values of 4 4 nM and 10 4 nM for CDK8/Cyclin C and CDK19/CyclinC respectively
Selleck Chemical LLC Nuzhenide S9473-1MG
Nuzhenide (Specnuezhenide) a major component of olive seeds is a member of the class of compounds known as saccharolipids It has strong antioxidant activity