Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

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6,571 – 6,585 of 60,541 results

6,571

Cayman Chemical rac-Benpyrine, Purity: ≥98%, CAS: 1333714-43-4, 5 mg

An inhibitor of the TNF-α-TNFR1 protein-protein interaction (IC50 = 0.109 µM); reduces TNF-α induced cytotoxicity in L-929 fibroblasts at 10 µM; prevents nuclear translocation of NF-κB in RAW 264.7 macrophages; improves survival in a mouse model of LPS-induced endotoxemia and decreases disease severity in mouse models of collagen-induced arthritis and imiquimod-induced psoriasis at 25 mg/kg

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6,572

Medchemexpress LLC Phenanthrene (Standard) | 85-01-8 | 99.6% | 5 G

Phenanthrene (Standard) is the analytical standard of Phenanthrene, intended for research and analytical applications. It is an orally active polycyclic aromatic hydrocarbon (PAH) that induces inflammation, oxidative stress, and apoptosis. Additionally, phenanthrene is commonly used to detect or assess PAH pollution in the environment.

The compound is the grade of analytical standard, which is the reference standard supplied assay.
It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

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6,573

TARGETMOL CHEMICALS INC DIABZI STING AGONIST-1 T 5MG

Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. diABZI STING agonist-1 (Tautomerism) (diABZI STING agonist (Compound 3)) is a selective stimulator of interferon genes (STING) receptor agonist with EC50s of 130 186 nM for human and mouse respectively. purity: 99%

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6,574

Cayman Chemical iBET-BD2, Purity: ≥98%, CAS: 2474876-09-8, 10 mg

A BD2 bromodomain inhibitor; inhibits BD2 in BRD2, BRD3, BRD4, and BRDT (IC50s = 264, 98, 49, and 214 nM, respectively) and is selective for BD2 over BD1 (IC50s = 10.96, 36.31, 70.55, and >50.11 µM for BRD2, BRD3, BRD4, and BDT, respectively) in a TR-FRET assay; inhibits IFN-γ-induced protein expression of MHC class I in K562 cells at 1 µM; reduces the production of anti-KLH IgM antibodies in mice immunized with KLH at 40 mg/kg

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6,575

eMolecules 2828432-46-6 | Medchem Express | CYN 154806 (TFA) | 1mg | 455326372 | HY-P1202A | MFCD11045909 | 1311.37 | C58H69F3N12O16S2

Ambeed | Methyl 2-(isoquinolin-1-yl)acetate | 100mg | 600842309 | A522205 | 69582-93-0 | MFCD13194757 | 201.225 | C12H11NO2

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6,576

Cayman Chemical RR6, Purity: ≥98%, CAS: 1351758-37-6, 5 mg

A vanin-1 inhibitor (IC50 = 0.54 µM for the recombinant human enzyme); selective for vanin-1 over biotinidase, cathepsin B, cathepsin L, and papain (IC50s = >200 µM for all); active against P. falciparum (IC50 = 14.5 µM); reduces plasma levels of cholesterol and increases plasma levels of free fatty acids in fasted rats at 3 mg/ml in the drinking water; decreases neointima formation and macrophage infiltration in aortic allografts in a rat model of transplant vasculopathy

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6,577

Cayman Chemical BQR-695, Purity: ≥98%, CAS: 1513879-21-4, 10 mg

An antimalarial compound; inhibits recombinant P. vivax and human PI4K (IC50s = 3.5 and 90 nM, respectively); induces schizont-stage arrest and death of P. falciparum (IC50 = ~70 nM)

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6,578

Cayman Chemical Methyllycaconitine (citrate), Purity: ≥98%, CAS: 351344-10-0, 5 mg

An antagonist of α7-containing nAChRs (Ki = 1.4 nM)

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6,579

Cayman Chemical MLN4760, Purity: ≥98%, CAS: 305335-31-3, 25 mg

An ACE2 inhibitor (IC50 = 0.44 nM); selective for ACE2 over ACE and CPDA (IC50s = >100 and 27 µM, respectively); inhibits ACE2 hydrolysis of angiotensin I in vitro at 1 µM; inhibits the protein-protein interaction between ACE2 and the SARS-CoV-2 spike glycoprotein; inhibits exogenous recombinant ACE2-induced prevention of angiotensin II-induced hypertension in mice

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6,580

Medchemexpress LLC Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, (3-phenoxyphenyl)methyl... | 26002-80-2 | 94.6% | 25 MG

Phenothrin is a Type I pyrethroid insecticide that induces dose-dependent DNA damage in human peripheral blood lymphocytes and hepatocytes, and exhibits definite genotoxic potential. It is used for pest control in agriculture, households, public health, and for eliminating human head lice infestations.

Type I pyrethroid insecticide
Induces dose-dependent DNA damage
Used for pest control in agriculture, households, public health
Eliminates human head lice infestations
Available in pure form for research use

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6,581

Medchemexpress LLC GLUT4-IN-2 | 2454113-83-6 | 99.2% | 385.42 | 25 MG

GLUT4-IN-2 is a potent and selective GLUT4 inhibitor with IC50s of 11.4 μM for GLUT1 and 6.8 μM for GLUT4. It induces cell apoptosis and cell cycle arrest at the G0/G1 phase, and demonstrates potent antitumor activity.

Potent and selective GLUT4 inhibitor
Induces cell apoptosis
Induces cell cycle arrest at G0/G1 phase
Demonstrates potent antitumor activity
Decreases expression of mTOR and CDK2 proteins
Increases expression of GRP78 and cleaved caspase 3 proteins

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6,582

Medchemexpress LLC 2S 7aR -2-Fluorote 50mg

((2S 7aR)-2-Fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol-d2 ((2S 7aR)-2-Fluorotetrahydro-1H-pyrrolizine-7a(5H)-methanol-d2) is the deuterium labeled ((2S 7aR)-2-Fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol

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6,583

Medchemexpress LLC Fluroxypyr | 69377-81-7 | 98.7% | 25 MG

Fluroxypyr is an auxin herbicide used to control annual or perennial weeds. It operates by inducing an overdose or excessive endogenous concentrations of auxin, which disrupts the normal auxin homeostasis and its interactions with other hormones within plant tissues.

It acts as an auxin herbicide.
It is effective against annual weeds.
It is effective against perennial weeds.
It causes an overdose of auxin in plants.
It disrupts auxin homeostasis.
It interferes with hormone interactions in plant tissues.

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6,584

Medchemexpress LLC HY-N5042 5mg Medchemexpress, Forsythoside I CAS:1177581-50-8 Purity:>98%

Medchemexpress, HY-N5042 5mg Forsythoside I CAS:1177581-50-8 Forsythoside I, a caffeoyl phenylethanoid glycoside (CPG) isolated from the fruits of Forsythia suspense (Thunb.) Vahl, may possesses anti-inflammatory activities. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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6,585

ABclonal Technology IRAK1 Rabbit pAb

This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Bioactive Small Molecules

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Medchemexpress LLC Phenanthrene (Standard) | 85-01-8 | 99.6% | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, (3-phenoxyphenyl)methyl... | 26002-80-2 | 94.6% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC GLUT4-IN-2 | 2454113-83-6 | 99.2% | 385.42 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2S 7aR -2-Fluorote 50mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Fluroxypyr | 69377-81-7 | 98.7% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-N5042 5mg Medchemexpress, Forsythoside I CAS:1177581-50-8 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

ABclonal Technology IRAK1 Rabbit pAb Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More