Bioactive Small Molecules
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (16)
- (2)
- (2)
- (2)
- (27)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (153)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (5)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (5)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (96)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (10)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (3)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (52)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (25)
- (9)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (63)
- (1)
- (2)
- (5)
- (271)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (7)
- (6)
- (1)
- (2)
- (2)
- (1)
- (3)
- (1)
- (91)
- (16)
- (8)
- (2)
- (9)
- (4)
- (2)
- (1)
- (3)
- (4)
- (2)
- (15)
- (2)
- (1)
- (9)
- (2)
- (4)
- (2)
- (2)
- (1)
- (2)
- (7)
- (1)
- (7)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
Filtered Search Results
Medchemexpress LLC Ebsulfur | 2527-03-9 | 99.4% | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Ebsulfur is a benzisothiazolone cytocidal inhibitor that targets the trypanothione reductase (TryR) of *Trypanosoma brucei*. It is used for research on African trypanosomiasis.
- Targets trypanothione reductase (TryR) of *Trypanosoma brucei*
- Has IC50 values of 61-293 nM for *Trypanosoma brucei*
- Used for research on African trypanosomiasis
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Cayman Chemical T-1095, Purity: ≥98%, CAS: 209746-59-8, 10 mg
An SGLT1 and SGLT2 inhibitor (IC50s = 22.8 and 2.3 µM, respectively); dietary administration reduces blood glucose and HbA1c levels in a rat model of streptozotocin-induced diabetes at 0.01% w/w; suppresses the development of hyperglycemia and hypertriglyceridemia and reduces HbA1c levels in the KKAγ mouse model of type 2 diabetes; exacerbates post-infarction cardiac dysfunction in a rat model of left anterior descending coronary artery ligation-induced myocardial infarction
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC ACDPP hydrochloride 1177808-75-1 10mg
ACDPP hydrochloride (CAS 1177808-75-1) is a selective antagonist of the metabotropic glutamate receptor 5 (mGluR5) By inhibiting mGluR5 signaling ACDPP hydrochloride modulates glutamatergic neurotransmission and has been utilized to investigate the molecular mechanisms underlying neurological and psychiatric disorders such as anxiety depression neuropathic pain and certain neurodegenerative diseases This compound serves as a valuable tool in preclinical studies focused on developing therapeutic strategies targeting mGluR5-mediated pathologies
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Phenyl sulfate | 937-34-8 | 99.5% | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Phenyl sulfate is an orally active gut microbiota-derived metabolite. It induces albuminuria and podocyte damage in podocyte damage in experimental models of diabetes. It can be used as a disease marker in diabetic kidney disease. This product is for research use only and not sold to patients.
- Orally active gut microbiota-derived metabolite
- Induces albuminuria and podocyte damage in experimental models of diabetes
- Functions as a disease marker in diabetic kidney disease
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Cayman Chemical st-Ht31 (ammonium salt), Purity: ≥98%, 5 mg
A cell-permeable stearated peptide; decreases PKA membrane anchoring but not activity in a reporter assay using BHK-21 fibroblasts at 50 µM; reduces capacitance, hyperactivation, as well as prevents in vitro fertilization, in mouse sperm at 1 and 3 µM; increases cholesterol export from ABCA1-expressing BHK-21 cells and RAW 264.7 macrophages at 50 µM
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Cayman Chemical CRT0273750, Purity: ≥98%, CAS: 1979939-16-6, 5 mg
An ENPP2 inhibitor (IC50 = 1 nM); prevents lysophosphatidylcholine hydrolysis in a plasma choline release assay (IC50 = 13 nM); inhibits the migration of 4T1 cells in migration assay (IC50 = 24 nM); decreases plasma levels of lysophosphatidic acid in an MDA-MB-231 mouse xenograft model
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Cayman Chemical CPYPP, Purity: ≥98% (mixture of isomers), CAS: 310460-39-0, 50 mg
An inhibitor of DOCK2 (IC50 = 22.8 µM for its GEF activity), DOCK5, and DOCK180; selective for these DOCKs over DOCK9; prevents chemokine-induced Rac activation in T and B cells at 100 µM; reduces migration of T cells to peripheral lymph nodes in mice at 5 mg/animal following adoptive transfer of spleen cells from knock-in mice expressing GFP-tagged DOCK2; reduces MPO activity in lung tissue, LPS-induced cytokine release in serum, and lung injury severity in a mouse model of endotoxemia-induced acute lung injury at 250 mg/kg
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC VUF11207 fumarate | 1785665-61-3 | 99.9% | 586.65 | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
VUF11207 fumarate is an agonist of CXCR7, a C-X-C motif chemokine receptor. It specifically binds to CXCR7 and has been shown to reduce CXCL12-mediated osteoclastogenesis and bone resorption. This reduction is achieved by inhibiting ERK phosphorylation. It is intended for research use only.
- Binds specifically to CXCR7
- Reduces osteoclastogenesis
- Decreases bone resorption
- Functions by inhibiting ERK phosphorylation
- High purity: 99.9%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Cayman Chemical D-threo-Biopterin, Purity: ≥98%, CAS: 13019-52-8, 5 mg
A pterin; enhances luminol chemiluminescence induced by the oxidant chloramine-T in a cell-free assay at 100 μM
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC Vatalanib (PTK787) 2HCl 212141-51-0 10mg
Vatalanib (PTK787) 2HCl (CAS 212141-51-0) is a small molecule inhibitor targeting vascular endothelial growth factor (VEGF) receptor tyrosine kinases including VEGFR/KDR (IC50 0 037 M) VEGFR/Flt-1 (IC50 0 077 M) and VEGFR/Flk (IC50 0 27 M) It also inhibits other receptor tyrosine kinases such as PDGFR- (IC50 0 58 M) c-Kit (IC50 0 73 M) and c-Fms (IC50 1 4 M) Through blockade of these pathways Vatalanib suppresses VEGF-mediated signaling and angiogenesis It is utilized in research investigating mechanisms of angiogenesis and has potential applications in studies of solid tumors and other angiogenesis-dependent diseases
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Dehydroascorbic acid | 490-83-5 | 95.0% | 174.11 | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Dehydroascorbic acid is an oxidized form of vitamin C that can cross the blood-brain barrier (BBB). It clears cytotoxic reactive oxygen species (ROS) produced after ischemic stroke by converting to ascorbic acid (AA), thereby reducing neuronal and glial cell damage and stabilizing cerebral microvascular NO signaling to maintain perfusion in the ischemic area. It can be used in research on ischemic stroke.
- Crosses the blood-brain barrier
- Clears cytotoxic reactive oxygen species (ROS)
- Reduces neuronal and glial cell damage
- Stabilizes cerebral microvascular NO signaling
- Maintains perfusion in the ischemic area
- Used in research on ischemic stroke
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Selleck Chemical LLC Dittany Bark Extract E3035-5MG
Dittany Bark Extract is extracted from the bark of Dittany which is often used in treating inflammation bacterial and fungal infections reducing inflammation and digestive health
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC IP7e | 500164-74-9 | 99.65% | 390.43 | 1 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
IP7e is a potent, brain-penetrant, and orally active Nurr1 activator with an EC50 value of 3.9 nM. It is intended for research use only and not for patient use.
- Potent Nurr1 activator.
- Brain-penetrant.
- Orally active.
- Reduces the incidence and severity of experimental autoimmune encephalomyelitis (EAE) in mice with preventive treatment.
- Attenuates inflammation and neurodegeneration in the spinal cords of EAE mice through an NF-kB pathway-dependent process.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC L-selectin/CD62L Cy 100ug | 100ug
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
L-selectin/CD62L is a calcium-dependent lectin that aids cell adhesion by binding to neighboring glycoproteins It mediates lymphocyte adhesion to endothelial cells in peripheral lymph nodes causing leukocytes to tether and roll L-selectin/CD62L Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived L-selectin/CD62L protein expressed by HEK293 with C-His labeled tag
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 117279-73-9 | ISRAPAFANT | J & W PharmLab LLC | MFCD00873428 | 489.080 | C28H29ClN4S | 96.000 | CC(C)Cc1ccc(CCc2cc3c(s2)-n2c(C)nnc2C(C)N=C3c2ccccc2Cl)cc1 | 10mg | 416222983
ISRAPAFANT | J & W PharmLab LLC | 117279-73-9 | MFCD00873428 | 489.080 | C28H29ClN4S | 96.000 | CC(C)Cc1ccc(CCc2cc3c(s2)-n2c(C)nnc2C(C)N=C3c2ccccc2Cl)cc1 | 10mg | 416222983
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More