Bioactive Small Molecules
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Filtered Search Results
Apexbio Technology LLC HATU, 25g. Cas: 148893-10-1 MFCD: MFCD00274639. used in peptide coupling chemistry
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HATU(1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate) is a reagent used inpeptide couplingchemistry to generate an active ester from a carboxylic acid. Other sizes are available. Please inqury us for quote.
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Apexbio Technology LLC A922500, 5mg. Cas: 959122-11-3 MFCD: MFCD12828780. DGAT-1 inhibitor
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A922500 is a potent, active, selective and orally bioavailable inhibitor of diacylglycerol acyltransferase-1 (DGAT-1). It is a small molecular with the formula of C26H24N2O4 and molecular weight of 428.48. Other sizes are available. Please inqury us for quote.
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Apexbio Technology LLC Wortmannin, 20mg. Cas: 19545-26-7 MFCD: MFCD00133927. PI3K inhibitor,selective and irreversible
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Wortmannin is a selective and irreversible inhibitor of phosphatidylinositol-3-kinase with IC50 value of 1.9nM [1].Wortmannin is a microbial product. Other sizes are available. Please inqury us for quote.
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Apexbio Technology LLC Terbinafine, 100mg. Cas: 91161-71-6 MFCD: MFCD00242672. Allylamine antifungal agent
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Terbinafine is an allylamine antifungal agent which has fungicidal activity against a wide variety of dermatophytes, moulds and certain dimorphic fungi, and fungistatic activity against Candida albicans. Other sizes are available. Please inqury us for quote.
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Apexbio Technology LLC InstaBlue Protein Stain Solution, 500ml. Cas: MFCD: MFCD00078482. For ultrafast protein gel staining
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InstaBlue Protein Stain Solution is a ready to use Coomassie protein stain for polyacrylamide gels. Its unique patented mechanism of action stains proteins in 5 minutes while leaving a clear background without the need to fix, wash or destain. InstaBlue Protein Stain Solution is formulated for safe use and easy disposal. InstaBlue Protein Stain Solution is very convenient for use and needs only simple one step protocol to finish the rapid coomassie blue staining of protein gels. Some premade and traditional home-made Coomassie R-250 protein stains can take 3 hours or more to fully stain gels. Because of InstaBlues protein specific staining which gives a clear background, improving the signal/noise ratio of the stain, InstaBlue Protein Stain Solution has high sensitivity and can detect protein levels as low as 5 ng per band when staining overnight. Other sizes are available. Please inqury us for quote.
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Apexbio Technology LLC Dehydroepiandrosterone (DHEA), 10g. Cas: 53-43-0 MFCD: MFCD00003613. Endogenous steroid hormone
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Dehydroepiandrosterone (DHEA) is an important endogenous steroid hormone [1].DHEA is an important endogenous steroid hormone and functions as a metabolic intermediate in the biosynthesis of estrogen and androgen. Other sizes are available. Please inqury us for quote.
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Apexbio Technology LLC Donepezil HCl, 5g. Cas: 120011-70-3 MFCD: MFCD00881312. AChE inhibitor
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Donepezil Hydrochloride (Donepezil HCL) is a novel, potent and selective inhibitor of acetylcholinesterase (AChE), an enzyme possibly involved in cognitive dysfunction of patients suffering Alzheimers disease (AD), with the half maximal inhibition concentration IC50 value of 6.7 nM [1]. Other sizes are available. Please inqury us for quote.
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Apexbio Technology LLC JSH-23, 25mg. Cas: 749886-87-1 MFCD: MFCD09753595. NF-κB inhibitor
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JSH-23 is an inhibitor of NF-B transcriptional activity with IC50 value of 7.1M [1].JSH-23 is developed to inhibit NF-B transcriptional activity in LPS-stimulated macrophages RAW 264.7. Other sizes are available. Please inqury us for quote.
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Selleck Chemical LLC GSK2606414
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GSK2606414 is an orally available potent and selective PERK inhibitor with IC50 of 0 4 nM displaying at least 100-fold selectivity over the other EIF2AKs assayed GSK2606414 impairs GANT-61 induced autophagy in NB cells with MYCN amplification GSK2606414 exacerbates ER stress-induced apoptosis in HCT116 cells while reduces the apoptosis in SIL1 KD HeLa cells
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Selleck Chemical LLC Pexidartinib
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Pexidartinib (PLX3397) is an oral potent multi-targeted receptor tyrosine kinase inhibitor of CSF-1R Kit (c-Kit) and FLT3 with IC50 of 20 nM 10 nM and 160 nM respectively Pexidartinib (PLX3397) induces apoptosis and necrosis with antitumor activity Phase 3
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Selleck Chemical LLC Pevonedistat
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MLN4924 is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with IC50 of 4 nM
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Selleck Chemical LLC Selonsertib
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Selonsertib (GS-4997) is a highly selective and potent once-daily oral ASK1 inhibitor with potential anti-inflammatory antineoplastic and anti-fibrotic activities
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Selleck Chemical LLC Napabucasin
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Napabucasin (BBI608) is an orally available Stat3 and cancer cell stemness inhibitor
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Selleck Chemical LLC Pritelivir
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Pritelivir (BAY 57-1293 AIC316) is a potent helicase primase inhibitor exhibiting antiviral effect on herpes simplex virus (HSV) with IC50 of 20 nM for both HSV-1 and HSV-2
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Selleck Chemical LLC Ulixertinib
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Ulixertinib (BVD-523 VRT752271) is a potent and reversible ERK1/ERK2 inhibitor with IC50 of 0 3 nM for ERK2 Phase 1
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