Bioactive Small Molecules
Apexbio Technology LLC Steviolbioside, 50mg CAS# 41093-60-1
Steviolbioside is a rare sweetener that is also present in Stevia rebaudiana leaves. Stevioside has inhibitory effects on several human cancer cells and may be used as a treatment for human breast cancer. Stevioside has a moderate anti-tuberculosis activity against M. tuberculosis strain H37RV in vitro. Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC Sophorose monohydrate | 140686-17-5 | 99.9% | 1 MG
Sophorose monohydrate is a chemically defined disaccharide (CAS 140686-17-5) supplied as a solid for research applications. The material is provided in small weighed packs and is accompanied by analytical documentation, including a certificate of analysis and safety data sheet.
- Purity: 99.9%.
- Molecular weight: 360.31 g/mol.
- Chemical formula: C12H24O12.
- Physical form: solid, white to off-white.
- Available small pack sizes, including 1 mg and 5 mg.
- Supplied with COA and SDS documentation.
Medchemexpress LLC Gentisin | 437-50-3 | 1 MG
Gentisin is a natural compound extracted from Gentianae radix (Gentianaceae). It exhibits mutagenic activity and can be utilized in vascular smooth muscle research. It inhibits PDGF-induced vascular smooth muscle cell proliferation in a concentration-dependent manner with an IC50 of 7.84 μM. It also shows cytotoxicity against Taxol-resistant human A549 cells (IC50: 103.76 μM), human MCF7/ADR cells (IC50: 31.82 μM), and Taxol-resistant human SMMC7721 cells (IC50: 87.44 μM) after 48 hours as measured by MTT assay.
- For research use only.
- Available in multiple sizes.
- In stock for 1 mg size.
- Data Sheet, COA, SDS, handling instructions, and technical support available.
- In vivo dissolution calculator and Help & FAQs available.
- Related screening libraries available.
- Related small molecules listed.
Medchemexpress LLC WEHI-345 | 1354825-58-3 | 99.31% | 401.46 | 1 ML
WEHI-345 is a potent and selective RIPK2 kinase inhibitor with an IC50 of 0.13 μM. It delays RIPK2 ubiquitylation and NF-κB activation on oligomerization domain (NOD) stimulation.
- Potent and selective RIPK2 kinase inhibitor.
- IC50 of 0.13 μM against RIPK2.
- Delays ubiquitylation and NF-κB activation on oligomerization domain (NOD) stimulation.
Cayman Chemical SCH 442416, Purity: ≥98%, CAS: 316173-57-6, 25 mg
A potent, brain-permeable, and selective A2AR antagonist; selective for A2AR over A1R, A2BR, and A3R (Kis = 0.048, 1,111, >10,000, and >10,000 nM, respectively) using human recombinant receptors; selective for A2AR over A1R and A3R in rat cerebral membranes (Kis = 0.50, 1,815, and >10,000 nM, respectively); is taken up preferentially by liver, adrenal gland, kidney, and lungs, and by the striatum in the brain; attenuates adenosine-mediated and A2AR agonist-induced arteriole dilation at a concentration of 10 μM
Medchemexpress LLC 1H-indole, 1-methyl- | 603-76-9 | MFCD00005800 | 99.9% | 131.18 g/mol | C9H9N | 25g
1-Methylindole is an intermediate 1-Methylindole can be used in the synthesis of 1-Methyl-indole-3-carboxaldehyde 1-Methyl-indole-3-carboxaldehyde has anti-Toxoplasma activity[1]
Medchemexpress LLC 2-Methylcyclohexanone | 583-60-8 | MFCD00001635 | 98.9% | 112.17 | 50 G
2-Methylcyclohexanone is a chemical compound primarily used for laboratory research and substance manufacturing. It is a colorless to light yellow liquid with a molecular weight of 112.17 and a purity of 98.9%. This product is for research use only and should be handled by experienced personnel.
- Consistent with structure
- Suitable for laboratory research
- Recommended storage at -20°C for 3 years (pure form) or 4°C for 2 years
- Recommended storage in solvent at -80°C for 6 months or -20°C for 1 month
- Can be shipped at room temperature if less than 2 weeks
- Colorless to light yellow liquid appearance
TARGETMOL CHEMICALS INC MD2-TLR4-IN-1 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor. purity: 99%
Cayman Chemical N-Methyl-4-pyridone-5-carboxamide, Purity: ≥95%, CAS: 769-49-3, 5 mg
A metabolite of nicotinic acid and a uremic toxin; plasma levels are increased and positively correlated with serum levels of MDA in patients with CKD
Cayman Chemical (R)-Ofloxacin, Purity: ≥98%, CAS: 100986-86-5, 5 mg
A fluoroquinolone antibiotic; the (R) isomer of ofloxacin and levofloxacin; active against certain Gram-positive and Gram-negative bacteria, including E. coli, P. aeruginosa strains 32104 and 32122, S. aureus strains 209P and Smith, and S. epidermis strain 56556 (MICs = 0.78, 12.5, 6.25, 25, 12.5, and 25 µg/ml, respectively) but not S. epidermis strain 56500, S. pyogenes, or S. faecalis (MICs = >100 µg/ml for all); inhibits E. coli DNA gyrase with an IC50 value of 75 µg/ml, which is approximately 30- and 50-fold lower than inhibition by ofloxacin and levofloxacin, respectively
Cayman Chemical 1-Docosahexaenoyl-2-hydroxy-sn-glycero-3-PC, Purity: ≥95% (as an 8:2 mixture of the 1-acyl and 2-acyl), CAS: 162440-05-3, 5 mg
A lysophospholipid; has been found in shark liver extract; decreases LPS-induced increases in the levels of TNF-α and IL-6 in RAW 264.7 cells; decreases LPS-induced NO production in RAW 264.7 cells from 12-200 µM; inhibits zymosan A-induced plasma leakage into the peritoneum in a mouse model of peritonitis from 15-500 µg/kg
Enzo Life Sciences Diazoxide (500mg). CAS: 364-98-7
ATP-sensitive K+ channel activator. Effective concentrations in patch clamp experiments: 100-600µM. Blocks desensitization of AMPA receptors. Acts in pancreatic β-cells, where it is more potent than pinacidil (ALX-550-285). Antihypertensive and vasodilatory agent. Alternative name: 7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (25mg/ml); insoluble in water. Long Term Storage: +4°C.
Medchemexpress LLC DfTat | 2035480-78-3 | 99.5% | 4076.83 | 5 MG
DfTat is a dimer of the prototypical cell-penetrating peptide TAT. It can efficiently deliver small molecules, peptides, and proteins into live cells. When labeled with rhodamine, DfTat can be used as a tracer for easy detection.
- Dimer of cell-penetrating peptide TAT
- Delivers small molecules, peptides, and proteins into live cells
- Offers high efficiency for delivery
- Labeled with rhodamine for easy detection
Medchemexpress LLC Corilagin, a gallotannin | 23094-69-1 | 634.45 | 20 MG
Corilagin, a gallotannin, exhibits anti-tumor, anti-inflammatory, and hepatoprotective activities. It inhibits the activity of reverse transcriptase of RNA tumor viruses and the growth of *Staphylococcus aureus* (MIC of 25 μg/mL). Corilagin also demonstrates anti-tumor activity in hepatocellular carcinoma and ovarian cancer models, with low toxicity to normal cells and tissues.
- Purity: 99.96%
- Appearance: Solid
- Color: White to off-white
- Structure classification: Phenols, polyphenols
- Initial source: Plants, Euphorbiaceae, Phyllanthus urinaria Linn.
- Solubility in DMSO: 100 mg/mL (requires ultrasonic)
- Exhibits anti-tumor activity
- Exhibits anti-inflammatory activity
- Exhibits hepatoprotective activities
- Inhibits reverse transcriptase of RNA tumor viruses
- Inhibits growth of Staphylococcus aureus
- Shows low toxicity to normal cells and tissues
Cayman Chemical KDM4D-IN-1, Purity: ≥95%, CAS: 2098902-68-0, 5 mg
An inhibitor of JMJD2D (IC50 = 0.41 µM); selective for JMJD2D over JMJD1B, JMJD2B, and JARID1A (IC50s = >10 µM for all); decreases the colony formation, migration, and invasion of Caki-1 clear cell renal carcinoma cells and 786-O adenocarcinoma cells at 0.5 µM; reduces tumor growth and vessel development in a 786-O mouse xenograft model