Protein Modification Reagents
Medchemexpress LLC T-Boc-N-amido-PEG15-Br | 3012589-40-8 | 98.0% | C37H74BrNO17 | 100 MG
t-Boc-N-amido-PEG15-Br is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is intended for research use only. PROTACs contain two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC DBCO-PEG4-DBCO | 2182601-68-7 | 97.4% | 50 MG
DBCO-PEG4-DBCO is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It also functions as a cleavable ADC linker for the creation of antibody-drug conjugates (ADCs). This compound is a click chemistry reagent, featuring a DBCO group capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups.
- PEG-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Cleavable ADC linker.
- Used in the synthesis of antibody-drug conjugates (ADCs).
- Click chemistry reagent containing a DBCO group.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups.
Worthington Biochemical Corporation CARBOXY PEPTIDASE 5MG
Chromatographically purified. A solution in 100 mM sodium chloride. Chymotrypsin and trypsin 2 0.02%.
Medchemexpress LLC TCO-PEG-TCO | 97.1% | 25 MG
TCO-PEG-TCO is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, incorporating a TCO group that can engage in an inverse electron demand Diels-Alder reaction (iEDDA) with molecules possessing Tetrazine groups. PROTACs, composed of two distinct ligands connected by a linker, target an E3 ubiquitin ligase and a specific protein, leveraging the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Functions as a click chemistry reagent
- Incorporates a TCO group
- Engages in inverse electron demand Diels-Alder reaction (iEDDA)
- Leverages the intracellular ubiquitin-proteasome system
- For selective degradation of target proteins
Medchemexpress LLC Biotin-PEG4-amine | 663171-32-2 | 98.0% | C20H38N4O6S | 250 MG
Biotin-PEG4-amine is a biotin-labeled, PEG-based PROTAC linker. It is used in the synthesis of PROTACs, which are compounds designed to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. PROTACs consist of two different ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other to a target protein.
- Biotin-labeled compound
- PEG-based linker for PROTAC synthesis
- Utilized in targeted protein degradation
- Leverages the ubiquitin-proteasome system
- Designed with two ligands for E3 ubiquitin ligase and target protein binding
Medchemexpress LLC 3,6,9,12-Tetraoxatetradecanoic acid, 14-hydroxy- | 70678-95-4 | ≥97.0% | C10H20O7 | 250 MG
Hydroxy-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC TCO-PEG4-NHS ester | 1621096-79-4 | 99.2% | C24H38N2O10 | 25 MG
TCO-PEG4-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. This compound functions as a click chemistry reagent, featuring a TCO group that facilitates an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. PROTACs are composed of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- TCO group facilitates inverse electron demand Diels-Alder reaction (iEDDA) with Tetrazine groups
- Utilizes intracellular ubiquitin-proteasome system to selectively degrade target proteins
- For research use only
Chemscene ChemScene | Boc-NH-PEG4-CH2CH2NH2 | 1G | CS-W008352 | 0.97 | 811442-84-9| MFCD16619339 | 336.42
ChemScene | Boc-NH-PEG4-CH2CH2NH2 | 1G | CS-W008352 | 0.97 | 811442-84-9| MFCD16619339 | 336.42
Medchemexpress LLC Biotin-PEG4-TFP ester | 2985664-57-9 | 97.8% | C27H37F4N3O8S | 25 MG
Biotin-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein. This linker exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- For research use only
Medchemexpress LLC Biotin-PEG11-SH | 1650579-23-9 | 98.0% | C34H65N3O13S2 | 100 MG
Biotin-PEG11-SH enables biotin labeling of protein. It is intended for research use only and is not sold to patients. This product appears as an off-white to light yellow solid with a molecular weight of 788.02. It can be stored at -20°C under nitrogen or at -80°C for 6 months when in solvent.
- Enables biotin labeling of protein
- For research use only
- Appears as an off-white to light yellow solid
- Molecular weight: 788.02
- Can be stored at -20°C under nitrogen
- Soluble in DMSO at concentrations of ≥ 100 mg/mL
Medchemexpress LLC DSPE-PEG carboxylic acid (sodium) | 1403744-37-5 | 98.0% | (C2H4O)nC45H86NO12P.Na | 25 MG
DSPE-PEG Carboxylic acid (sodium), MW 2000 is a PEG-lipid that can be used in the preparation of drug delivery nanoparticles. It is capable of extending the blood circulation time and stability of liposomes, while also improving the targeting ability and cellular uptake efficiency of nanoparticles.
- Used in the preparation of drug delivery nanoparticles
- Prolongs the blood circulation time and stability of liposomes
- Enhances the targeting ability of nanoparticles
- Improves cellular uptake efficiency of nanoparticles
Medchemexpress LLC Azide-PEG2-Ms | 176520-23-3 | ≥97.0% | C5H11N3O4S | 250 MG
Azide-PEG2-Ms is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules possessing Alkyne groups. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker.
- Can be used in the synthesis of PROTACs.
- Click chemistry reagent.
- Contains an azide group.
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
Worthington Biochemical Corporation STEMXYME 2 COLLAGENASE 50MG
A specialized combination of Animal Origin-Free Clostridium histolyticum collagenase (Code: CLSAFB) and animal origin free Bacillus polymyxa neutral protease with a minimum of 250 CLS units and 2,000 caseinase units per mg dry weight. Designed for stem cell and other primary cell isolations and bioprocessing applications where introduction of potential animal derived pathogens must be prevented. 2593-92-3