Protein Modification Reagents
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Medchemexpress LLC Vh285-peg4-c4-cl (haloprotac 3) | 1799506-07-2 | 96.49% | 799.42 | 100 MG
VH285-PEG4-C4-Cl (HaloPROTAC 3) is a conjugate of ligands for E3 and a 16-atom-length linker. The connector of the linker is a Halogen group. It incorporates the VH285 based VHL ligand and an alkyl/ether-based linker. It is a highly potent and efficacious degrader of GFP-HaloTag7, binding to VHL.
- Highly potent and efficacious degrader of GFP-HaloTag7 with a DC50 of 19 nM.
- Able to induce 90% degradation of GFP-Halotag at 625 nM.
- Binds to VHL with an IC50 of 0.54 μM.
- Treatment with 500 nM of the product is able to induce nearly complete knockdown of both HaloTag7-ERK1 and HaloTag7-MEK1.
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ABclonal Technology SREK1 Rabbit pAb
This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.