Protein Modification Reagents
Broadpharm BDP FL-PEG4-TCO | 2183473-16-5 | MFCD31580132 | 5mg
BDP FL-PEG4-TCO | Putity: 98% | MW: 662.6 | 2183473-16-5 | MFCD31580132 | 5mg
Medchemexpress LLC 2,2,3,3-tetramethyl-4,7,10,13-tetraoxa-3-silapentadecan-15-ol | 134179-40-1 | MFCD25424114 | 97.0% | 308.49 g/mol | C14H32O5Si | 1 G
TBDMS-PEG4-OH is a tert-butyldimethylsilyl-protected PEG4 alcohol used as a PEG-based linker for PROTAC synthesis. It provides a short, flexible polyethylene glycol spacer with a protected terminal hydroxyl for downstream functionalization in bifunctional molecules and conjugation chemistry.
- TBDMS-protected terminal hydroxyl for selective deprotection.
- PEG4 spacer provides flexibility and improved solubility.
- High purity (97.0%) suitable for research applications.
- Soluble in DMSO for common laboratory workflows.
- Available in small pack sizes appropriate for discovery-stage synthesis.
Cayman Chemical GEFITINIB-BASED PROTAC 3 10MG
A PROTAC comprised of gefitinib linked to VHL ligand 1; induces degradation of EGFR containing the activating mutation L858R or an exon 19 deletion (DC50s = 22.3 and 11.7 nM, respectively) but does not induce degradation of wild-type EGFR at ≤10 μM in cell-based assays
ABclonal Technology SREK1 Rabbit pAb
This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Medchemexpress LLC Alkyne Cholesterol | 1631985-09-5 | C26H40O | 1 MG
Alkyne Cholesterol is a modified lipid that functions as a click chemistry reagent containing an alkyne group. This terminal alkyne group enables highly specific linking reactions with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. It can be utilized for tracking cellular cholesterol metabolism and localization.
- Functions as a click chemistry reagent
- Contains a terminal alkyne group
- Facilitates specific linking reactions with azide-containing reagents
- Requires a copper-containing catalyst
- Used for tracking cellular cholesterol metabolism
- Used for tracking cellular cholesterol localization
Cayman Chemical dPE-PEG 2000-amInsodIum 10mg
A PEGylated derivative of DSPE; has been used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents; has been used in the synthesis of fluorescein isothiocyanate-loaded mesoporous silica nanoparticles for imaging applications; can be conjugated to a variety of functional molecules for improved cellular targeting and uptake of DSPE-PEG(2000)-amine-containing nanoparticles
Cayman Chemical VH 032 LInker 2 10mg
A VHL Ligand 1 derivative; comprises the VHL ligand domain and PEG linker of the BET inhibitor-containing PROTACs MZ2 and MZP-55
Gold Biotechnology Inc Guanidine HCl 5 kg
Guanidine HCl is a freely soluble chaotropic agent routinely used for protein denaturation and folding.