Protein Purification

MilliporeSigma™ Calbiochem™ PI 3-Kδ Inhibitor X, IC87114

The PI 3-Kδ Inhibitor X, IC87114, also referenced under CAS 371242-69-2, controls the biological activity of PI 3-Kδ. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MilliporeSigma™ Calbiochem™ CXCR4 Antagonist IV, TF14016

A 14-aa internally disulfide-bonded peptide that potently competes against SDF-1α/CXCL12 for CXCR4 binding (IC₅₀

MilliporeSigma™ Calbiochem™ Microcystin-LW, Microcystis aeruginosa

Analog of Microcystin-LR with Trp substituted in place of Arg. Believed to be more cell-permeable than other microcystins making it useful for biochemical studies in intact cells.

MilliporeSigma™ Calbiochem™ O-GlcNAcase Inhibitor, TMG

A cell-permeable, blood-brain barrier-permeant, orally active aminothiazoline that effectively increases O -GlcNAc level of cellular proteins both in cultures (EC₅₀ = 30 nM, EC_max = 200nM in PC3) in vitro and in rats

MilliporeSigma™ Calbiochem™ Histone Acetyltransferase Activator, CTB

The Histone Acetyltransferase Activator, CTB, also referenced under CAS 451491-47-7, modulates the biological activity of Histone. This small molecule/inhibitor is primarily used for Cell Structure applications.

MilliporeSigma™ Calbiochem™ PKA Inhibitor 14-22 Amide, Cell-Permeable, Myristoylated

PKA Inhibitor 14-22 Amide is myristoylated at the N-terminus that enhances its cell-permeability. The non-myristoylated version is shown to be a specific inhibitor of PKA (Ki = 36 nM).

MilliporeSigma™ Calbiochem™ JNK Inhibitor V

The JNK Inhibitor V, also referenced under CAS 345987-15-7, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Thermo Scientific™ CaptureSelect™ AAT-XL Affinity Matrix

Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”

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Thermo Scientific™ CaptureSelect™ AAT-XL Affinity Matrix has been specifically designed for the purification of native human alpha-1 antitrypsin (AAT) from complex sources like plasma/serum and recombinant human AAT from cell culture supernatants.

MilliporeSigma™ Calbiochem™ PDE5 Inhibitor, Cpd7a

A cell-permeable, highly potent and selective inhibitor of phosphodiesterase 5 (PDEV; IC₅₀ = 270 pM).

MilliporeSigma™ Calbiochem™ Casein Kinase II Inhibitor I

The Casein Kinase II Inhibitor I, also referenced under CAS 17374-26-4, controls the biological activity of Casein Kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MilliporeSigma™ Calbiochem™ Caspase Modulator II, 1541B

Caspase Modulator II, 1541B primarily used in Inhibition.

MilliporeSigma™ Calbiochem™ Photochromic TrpA1 Channel Activator, Optovin

A rhodanine-derived, reversible, photoactivated, TrpA1-selective channel activator.

MilliporeSigma™ Benzonase Nuclease

GSA/VA Contract
Available on GSA/VA contract for Federal Government customers.
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MilliporeSigma™ Calbiochem™ ATM/ATR Kinase Inhibitor

The ATM/ATR Kinase Inhibitor, also referenced under CAS 905973-89-9, controls the biological activity of ATM/ATR Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MilliporeSigma™ Novagen™ Streptavidin Agarose

Consists of cross-linked agarose covalently coupled with pure streptavidin.