Protein Purification
MilliporeSigma™ Calbiochem™ γ-Secretase Substrate, Fluorogenic
An internally quenched fluorogenic peptide substrate containing the C-terminal β-APP (amyloid β-peptide precursor protein) amino acid sequence that is cleaved by γ-secretase.
MilliporeSigma™ Calbiochem™ STAT3 Inhibitor VI, S3I-201
STAT3 Inhibitor VI, S3I-201, CAS 501919-59-1, is a cell-permeable compound that binds Stat3-SH2 domain and blocks Stat3 phosphorylation, dimerization, DNA-binding, & Stat3-dependent transcription.
MilliporeSigma™ Calbiochem™ InSolution™ Paclitaxel, Taxus sp.
Antitumor and anti-leukemic agent isolated from the bark of the yew tree
MilliporeSigma™ Calbiochem™ Topoisomerase II Inhibitor, BNS-22
The Topoisomerase II Inhibitor, BNS-22 controls the biological activity of Topoisomerase. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Phorbol-12-myristate-13-acetate
Phorbol-12-myristate-13-acetate, CAS 16561-29-8, is the most common phorbol ester. Activates PKC at nanomolar concentrations.
MilliporeSigma™ Calbiochem™ Plasminogen Activator Inhibitor-1, Mutant, Human, Recombinant
Primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ PDE4D Inhibitor, GEBR-7b
The PDE4D Inhibitor, GEBR-7b controls the biological activity of PDE4D. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ CTAP
A highly potent octapeptide that acts as a selective and brain penetrating bioavailableμ opioid receptor antagonist (IC50
MilliporeSigma™ Calbiochem™ SANT-1
A potent, cell-permeable antagonist of the Shh signaling pathway by binding directly to Smoothened, a distant relative of G protein-coupled receptors.
MilliporeSigma™ Calbiochem™ InSolution™ SB 202190
A potent and cell-permeable inhibitor of p38 MAP kinase
MilliporeSigma™ Calbiochem™ Protein Arginine N-Methyltransferase Inhibitor, AMI-1
The Protein Arginine N-Methyltransferase Inhibitor, AMI-1 controls the biological activity of Protein Arginine N-Methyltransferase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ ATRA-BA Hybrid
The differentiation-inducer all-trans-Retinoic Acid and the histone deacetylase inhibitor (HDI) Butyric Acid.
MilliporeSigma™ Calbiochem™ InSolution™ SU5402
Inhibits the tyrosine kinase activity of FGFR1 (IC50 = 10-20μM in the presence of 1mm ATP) by interacting with the catalytic domain of FGFR1
MilliporeSigma™ Calbiochem™ InSolution™ STAT3 Inhibitor VI, S3I-201
The InSolution™ STAT3 Inhibitor VI, S3I-201, also referenced under CAS 501919-59-1, controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ SMER28
A cell-permeable quinazoline compound that augments the cytostatic effects of Rapamycin and acts as an autophagy stimulator both in mammalian cultures