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This locus controls the synthesis of the Kell blood group precursor substance (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins.
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KRAS G12D inhibitor 1 is a potent, selective small-molecule inhibitor of the oncogenic KRAS G12D mutant for preclinical research. It demonstrates subnanomolar biochemical potency and cellular activity and is supplied as solid material and as a DMSO stock for laboratory use.
Potent inhibition of KRAS G12D (IC50 = 0.4 nM in biochemical assay).
PF-07321332 is an orally active covalent inhibitor of the 3C-like protease by direct binding of the catalytic cysteine 145. 3CL protease cleaves polyproteins 1a and 1ab of SARS-CoV-2, a step required for reproduce the virus. The PF-07321332/ritonavir combination drug (trade name Paxlovid) is efficient for the treatment of COVID-19 as, in November 2021, Pfizer announced phase 2/3 clinal trial results that the drug treatment reduced 89% in hospitalizations when given within three days after symptom onset. This product is for research use only.
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GMP ActiveMax Human T cell Activation/Expansion CD3/CD28 Beads are uniform 5.5 μm of magnetic beads coated with an optimized mixture of GMP grade mouse monoclonal antibodies against the CD3 and CD28, mimicking in vivo stimulation by APCs.GMP ActiveMax Human T cell Activation/Expansion CD3/CD28 Beads are Manufactured under a GMP compliance factory with animal free raw materials, and tested under GMP guidelines.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More