Protein Purification
CPC Scientific Ac-Asp-Glu-Val-Asp-CMK 5MG
ONE-LETTER SEQUENCE: Ac-DEVD-CMKMOLECULAR FORMULA: C21H31N4O11Cl1MOLECULAR WEIGHT:550.95STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [285570-60-7], SYNONYMS: Ac-Asp-Glu-Val-Asp-chloromethylketoneRESEARCH AREA: Apoptosis
Medchemexpress LLC Cathepsin Inhibitor 2 | 1017931-53-1 | 421.38 | 5 MG
Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor, demonstrating a Ki of <20 nM. It also potently inhibits Cathepsin F, Cathepsin L, and Cathepsin B with Kis of 21-500 nM. This product is for research use only.
- Potent Cathepsin S inhibitor (Ki: <20 nM)
- Inhibits Cathepsin F, Cathepsin L, and Cathepsin B (Kis: 21-500 nM)
- Suitable for research use only
Medchemexpress LLC Trequinsin hydrochloride | 78416-81-6 | MFCD01076563 | 99.86% | 441.95 | 50 MG
Trequinsin hydrochloride (HL 725) is an extremely potent inhibitor of platelet CAMP phosphodiesterase (PDE), with an IC50 of 0.25 nM. It is also an extremely potent inhibitor of the aggregation of human platelets induced in vitro by ADP, collagen, thrombin, and epinephrine. Trequinsin hydrochloride exerts potent antiplatelet activities and is an efficacious agonist of [Ca2+]i.
- Extremely potent inhibitor of platelet CAMP phosphodiesterase (PDE)
- Inhibits aggregation of human platelets induced by ADP, collagen, thrombin, and epinephrine
- Exerts potent antiplatelet activities
- Efficacious agonist of [Ca2+]i
Medchemexpress LLC GPRP acetate | 157009-81-9 | 98.9% | 485.53 | 10 MG
GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa). This product is for research use only.
- Inhibits fibrin polymerization.
- Inhibits interaction of fibrinogen with platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa).
- Increases free thrombin generation in vitro.
- Alleviates DSS-induced colitis in vivo.
Medchemexpress LLC Neutral protease, Paenibacillus polymyxa | 42613-33-2 | 33.2 kDa (monomer); 66.3 kDa (dimer) | Not applicable - protein (no single chemical formula) | 5 MG
Neutral protease, Paenibacillus polymyxa is a bacterial neutral metalloprotease used in research to selectively cleave extracellular matrix proteins such as fibronectin and type IV collagen. Supplied as a white to off-white solid, it is commonly used for tissue dissociation, separation of epidermis from dermis, and release of intact epithelial sheets in culture. Refer to the certificate of analysis for recommended storage and specific activity data.
- Neutral metalloprotease active against fibronectin and type IV collagen.
- Suitable for tissue dissociation and separation of epidermis from dermis.
- Enzyme activity ≥ 0.5 U/mg (solid), unit definition provided.
- White to off-white solid formulation for laboratory use.
- Shipped at room temperature; follow COA for storage conditions.
Medchemexpress LLC B I09 10mg | 1607803-67-7 | 10MG
B I09 is an IRE-1 RNase inhibitor with an IC50 of 1230 nM
Sigma Aldrich Fine Chemicals Biosciences Akt1/2 kinase inhibitor 9825MG
Akt1/2 kinase inhibitor 9825MG
Cayman Chemical PD-1PD-L1 InhIbItr 1 5mg
A PD-1/PD-L1 interaction inhibitor; inhibits the PD-1/PD-L1 interaction in a TR-FRET assay (IC50 = 6-100 nM); reduces LPS-induced increases in PD-1 levels and apoptosis in MH-S mouse alveolar macrophages at 1 µM; surgical neointimal patching with PD-1/PD-L1-coated patches decreases neointimal thickness and inflammatory cell accumulation in a rat model of patch angioplasty
Abcam Gabe x ate mesylate, General serine protease inhibitor, 10MG
MW 417.5 Da, Purity >99%. General serine protease inhibitor (Ki values are 3.4 nM, 5, 1.8 μM and 2.6 mM at tryptase, thrombin, tyrpsin and kallikrein serine proteases respectively). Additionally inhibits nitric oxide synthase. Displays antithrombotic activity and antitumor effect. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Selleck Chemical LLC Epirubicin HCl 25mg 56390-09-1 4'-epidoxorubicin HCl
Epirubicin HCl (4'-epidoxorubicin), a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase. Epirubicin induces apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Cayman Chemical mP-9mP-13 InhIbItr I 1mg
A cell-permeable inhibitor of MMPs that most potently inhibits MMP-9 and MMP-13 (IC50s = 0.9 nM for both); less effectively inhibits MMP-1, MMP-3, and MMP-7 (IC50s = 43, 23, and 920 nM, respectively)
Cayman Chemical Src KInase InhIbItr I 1mg
A potent competitive inhibitor of both Src and Lck (IC50 = 44 and 88 nM, respectively), as well as Csk and Yes; also inhibits RIP-2
Cayman Chemical JAK2 InhIbItr V 10mg
A selective inhibitor of the autophosphorylation of wild type and V617F mutant forms of JAK2, displaying IC50 values between 10 and 30 µM; blocks the proliferation of erythroleukemia cells and human hematopoietic progenitor cells expressing JAK2-V617F
Cayman Chemical GlutamInase C InhIbItr 11 5mg
An inhibitor of GAC; inhibits GAC enzyme activity (EC50 = 10.64 nM); reduces the viability of A549 NSCLC cells (IC50 = 4.025 nM); reduces colony formation by, and intracellular glutamate levels in, A549 cells at 0.1 and 1 µM; reduces tumor growth in an A549 mouse xenograft model at 100 mg/kg