Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ MAS 7
A cell-permeable, amphiphilic, mastoparan analog with five-fold greater potency than Mastoparan.
MilliporeSigma™ Calbiochem™ InSolution™ Tamoxifen, 4-Hydroxy-, (Z)-
A 10 mM (2 mg/516 μL) sterile-filtered solution of (Z)-4-Hydroxytamoxifen in ethanol.
MilliporeSigma™ Calbiochem™ InSolution™ PERK Inhibitor I, GSK2606414
A cell-permeable pyrrolopyrimidinamine compound that acts as a highly potent inhibitor against EIF2AK3/PERK-catalyzed EIF2α Ser51 phosphorylation in kinase assays (IC50 = 0
MilliporeSigma™ Calbiochem™ Bestatin
Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase.
MilliporeSigma™ Calbiochem™ InSolution™ Trichostatin A, Streptomyces sp.
A potent and reversible inhibitor of histone deacetylase
MilliporeSigma™ Calbiochem™ TRPML Agonist, ML-SA1
The TRPML Agonist, ML-SA1 controls the biological activity of TRPML. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Aurora Kinase Inhibitor VI, ZM447439
The Aurora Kinase Inhibitor VI, ZM447439, also referenced under CAS 331771-20-1, controls the biological activity of Aurora Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ PI 3-K Inhibitor XXI, GDC-0941
A cell-permeable, potent, ATP-competitive inhibitor of class IA (IC50 = 3 nM/p110α, 33 nM/p110β, 3 nM/p110δ) and IB PI 3-kinases (IC50 = 75 nM/p110γ).
MilliporeSigma™ Calbiochem™ STAT3 Inhibitor VI, S3I-201
STAT3 Inhibitor VI, S3I-201, CAS 501919-59-1, is a cell-permeable compound that binds Stat3-SH2 domain and blocks Stat3 phosphorylation, dimerization, DNA-binding, & Stat3-dependent transcription.
MilliporeSigma™ Calbiochem™ Antipain, Dihydrochloride
Peptidyl arginine aldehyde protease inhibitor produced by actinomycetes.
MilliporeSigma™ Calbiochem™ Retro-2
A cell-permeable tricyclic imine compound that inhibits the endosome-to-Golgi retrograde transport, but not cellular uptake, of CtxB, StxB without affecting cellular uptake/trafficking of Tf or EGF.
MilliporeSigma™ Calbiochem™ Polo-like Kinase Inhibitor IV, SBE13
The Polo-like Kinase Inhibitor IV, SBE13, also referenced under CAS 775294-82-1, controls the biological activity of Polo-like Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Leukadherin-1
A furanyl thiazolidinone compound that binds CD11b αA/αI domain in a reversible manner and stabilizes αA in a high-affinity binding conformation toward known CD11b/CD18 (αMβ2; CR3; Mac-1) ligands, fibrinogen, ICAM-1, and iC3B.
MilliporeSigma™ Calbiochem™ Bexarotene
A retinoid X receptor (RXR) agonist that can permeate the blood-brain barrier and rapidly reduce Aβ40 and Aβ42 levels in APP/PS1 mice in an ApoE-dependent manner.
