Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Elastase Inhibitor II
The Elastase Inhibitor II controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ CL316243 Hydrate
A very potent agonist highly selective for β3 adrenoceptors (EC50 =
MilliporeSigma™ Calbiochem™ VEGFR2 Kinase Inhibitor VII, SKLB1002
The VEGFR2 Kinase Inhibitor VII, SKLB1002 controls the biological activity of VEGFR2 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ CGP 7930
A blood brain barrier permeable, positive allosteric modulator of the metabotropic GABAB recep
MilliporeSigma™ Calbiochem™ MK2a Inhibitor
The MK2a Inhibitor, also referenced under CAS 41179-33-3, controls the biological activity of MK2a. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ MCT1 Inhibitor, SR13800
A cell-permeable inhibitor of monocarboxylate transporter 1 (MCT1). Blocks the proliferation of Raji Burkitt lymphoma cells expressing MCT1 (EC50 = 5 nM).
MilliporeSigma™ Calbiochem™ TLR3/dsRNA Complex Inhibitor
The TLR3/dsRNA Complex Inhibitor blocks dsRNA binding to TLR3.
MilliporeSigma™ Calbiochem™ WAY-100635 Maleate
A selective 5-HT1A receptor antagonist (pKi
MilliporeSigma™ Calbiochem™ Fbxo3 Inhibitor, BC-1215
A cell-permeable, bis-pyridinylbenzylethanamine that disrupts Fbxo3-Fbxl2 interaction and effectively prevents SCF-Fbxo3-catalyzed Fbxl2 ubiquitination, resulting in cellular Fbxl2 upregulation and thereby SCF-Fbxl2-catalyzed TRAFs (TNF Receptor-Associated Factors) ubiquitination
MilliporeSigma™ Calbiochem™ Ellipticine
A cell-permeable antitumor alkaloid that acts as an inhibitor of topoisomerase II and acts as an intercalative agent that stimulates topoisomerase II-mediated DNA breakage.
MilliporeSigma™ Calbiochem™ Ras/Rac Transformation Blocker, SCH 51344
Ras/Rac Transformation Blocker, SCH 51344, CAS 171927-40-5, is a blocker of Ras-induced malignant transformation and Ras/Rac-dependent dissociation of EMS1 from the actin-myosin II complex.
MilliporeSigma™ Calbiochem™ Calpain-1 Substrate, Fluorogenic
An internally quenched fluorogenic substrate peptide derived from the calpain-1 cleavage site of α-spectrin.
MilliporeSigma™ Calbiochem™ PON1 Activator, ZNPA
The PON1 Activator, ZNPA modulates the biological activity of PON1. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ β-Catenin/Tcf Inhibitor VI, ICG-001
A cell-permeable pyrazinopyrimidinecarboxamide that competes against β-catenin for CBP (CREB-binding protein) binding and selectively prevents CBP- but not p300-, dependent TCF/β-catenin transcriptional regulations both in cultures in vitro (5 to 25μM) and in mice in vivo (5mg/kg/day via osmotic pump infusion), while not affecting CBP-dependent transcriptional activities mediated by the AP-1 or CRE c
MilliporeSigma™ Calbiochem™ Alsterpaullone
A cell-permeable, potent, reversible, and ATP competitive inhibitor of GSK-3β (IC50 = 4 nM) and Cdk1/cyclin B (IC50 = 35 nM).