Isotopically Labeled Compounds
Cambridge Isotope Laboratories Dimethyl Sulfoxide-D6 (D, 99.9%), .05% V/V Tms, 2206-27-1, Mfcd00002090, 10X0.6 Ml
This item has a minimum order quantity of 3 per supplier requirements
Dimethyl Sulfoxide-D6 (D, 99.9%), .05% V/V Tms, 2206-27-1, Mfcd00002090, 10X0.6 Ml
Medchemexpress LLC L-cysteine (13C3, 15N) | 202406-97-1 | MFCD01073449 | 99.9% | 125.13 | 13C3H7 15NO2S | 10mg
L-Cysteine-13C3 15N is the 13C- and 15N-labeled L-Cysteine L-Cysteine is a conditionally essential amino acid which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S) glutathione and taurine L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1]
Medchemexpress LLC 7-keto-Deoxycholic acid | 911-40-0 | 99.7% | 406.56 | 5 MG
7-keto-Deoxycholic acid is a metabolite of bile acids found in *Clostridium absonum*. It is also produced from *Lactobacillus* and *Bifidobacterium* under specific conditions. In vitro, its bioconversion rate increases with the addition of an equimolar concentration of deoxycholic acid. It is induced by deoxycholic acid and subsequently metabolized. For example, *E. lentum-like c-25* can convert cholic acid to deoxycholic acid and 7-keto-Deoxycholic acid under anaerobic incubation.
- Metabolite of bile acids.
- Can be converted from *Lactobacillus* and *Bifidobacterium*.
- Available in various quantities.
- High purity.
- Solid appearance, white to off-white color.
- Endogenous metabolite.
- Shipping at room temperature in continental US; storage at 4°C, protected from light.
- Soluble in DMSO.
Medchemexpress LLC Lomefloxacin-d5 hydrochloride | 98079-52-8 | 99.88% | 5 MG
Lomefloxacin-d5 (hydrochloride) is the deuterium-labeled Lomefloxacin hydrochloride. Lomefloxacin (SC47111A) hydrochloride is a broad-spectrum quinolone antibiotic with antimicrobial activity. It is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, and ENT infections. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration, involving the incorporation of stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules, is used as a tracer for quantitation during drug development and has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution can potentially influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Naratriptan-d3 hydrochloride | 1190021-64-7 | 1 MG
Naratriptan-d3 is a deuterium labeled form of Naratriptan hydrochloride, a selective 5-HT1B/1D receptor agonist. This compound is peripherally active and exhibits good oral bioavailability, inducing cranial artery vasoconstriction. It also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation, making it suitable for research into acute migraine, targeting cranial vascular and neuroinflammatory mechanisms.
- Used as a tracer
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Acts as a selective 5-HT1B/1D receptor agonist
- Exhibits good oral bioavailability
- Induces cranial artery vasoconstriction
- Inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation
- Reduces sterile inflammation
Medchemexpress LLC Acetic acid-1-13C | 1563-79-7 | MFCD00037366 | 100.0% | 61.04 g/mol | CH3 13CO2H | 100mg
Acetic acid-1-13C is 13C labeled Acetic acid-1
Medchemexpress LLC Clencyclohexerol-d10 | 1346599-61-8 | 99.5% | 329.29 | C14H10D10Cl2N2O2 | 5mg
Clencyclohexerol-d10 is the deuterium-labeled Clencyclohexerol (HY-117406) Clencyclohexerol-d10 is a -agonist Clencyclohexerol-d10 can be used as a growth promoter in animals[1]
Sigma Aldrich Fine Chemicals Biosciences Formaldehyde-13C solution 20 wt. % in H2O, 99 atom % 13C | 3228-27-1 | MFCD00144372 | 1G
Formaldehyde-13C solution 20 wt. % in H2O, 99 atom % 13C | Mol Wt: 31.02 | 3228-27-1 | MFCD00144372 | 1G
Medchemexpress LLC L-Carnitine-d9 chloride | 2687961-04-0 | 99.0% | 5 MG
L-Carnitine-d9 chloride is a deuterium-labeled L-Carnitine chloride. This highly polar, small zwitterion serves as an essential co-factor for the mitochondrial β-oxidation pathway, facilitating the transport of long-chain fatty acyl-CoAs into mitochondria for degradation. It also functions as an antioxidant and can alleviate metabolic imbalances in various inborn errors of metabolism.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration offers potential to influence pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Serotonin-d4 | 58264-95-2 | 99.6% | 1 MG
Serotonin-d4 is a deuterium labeled Serotonin, functioning as a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. It also acts as a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM. Stable heavy isotopes like deuterium are incorporated into drug molecules as tracers for quantitation during drug development, with potential to affect pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules for quantitation
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Methyl stearate-d35 | 29823-25-4 | 99.9% | 100 MG
Methyl stearate-d35 is the deuterium labeled Methyl stearate. Methyl stearate, isolated from Rheum palmatum L., is a component of soybean and rapeseed biodiesels. For research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Sigma Aldrich Fine Chemicals Biosciences 1-Octan-d17-ol 98 atom % D | 153336-13-1 | MFCD00144995 | 1G
1-Octan-d17-ol 98 atom % D | Purity: 99% (CP) | Mol Wt: 147.33 | 153336-13-1 | MFCD00144995 | 1G
Cayman Chemical AbIrateron Acetate-d4 10mg
An internal standard for the quantification of abiraterone acetate by GC- or LC-MS
Medchemexpress LLC Methyl stearate-d35 | 29823-25-4 | 99.9% | 50 MG
Methyl stearate-d35 is the deuterium-labeled version of Methyl stearate (HY-B1934), a compound isolated from Rheum palmatum L. and a component of soybean and rapeseed biodiesels. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules for use as tracers in drug development, and deuteration has shown potential to influence the pharmacokinetic and metabolic profiles of drugs.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.