Isotopically Labeled Compounds
Medchemexpress LLC D-Mannitol-13C | 132202-29-0 | 183.16 | 50 MG
D-Mannitol-13C is a 13C labeled form of D-Mannitol, an oral, resistant sugar with broad applications in food and pharmaceutical industries. It aids in calcium and magnesium absorption, acts as an osmotic diuretic to reduce tissue edema, and may enhance brown fat formation, improve insulin effect, and lower blood sugar. Additionally, it helps maintain osmotic pressure in plant cells and protects them when cell walls are compromised.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules for quantitation
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC 5-Methylcytosine-d4 | 1219795-15-9 | 129.15 | 5 MG
5-Methylcytosine-d4 is the deuterium labeled version of 5-Methylcytosine. 5-Methylcytosine is a known DNA modification in prokaryotes and eukaryotes. It forms symmetrical methylation on CpG dinucleotides in DNA, stabilizes tRNA/rRNA structure in RNA, and influences mRNA translation. It can be oxidized to produce 5hmC, 5fC, and 5caC. 5-Methylcytosine is used in epigenetics, developmental biology, and research on diseases such as colorectal cancer and hepatocellular carcinoma.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Benzyl alcohol-d1 (Benzenemethanol-d1) | 14915-25-4 | 95.7% | 50 MG
Benzyl alcohol-d1, also known as Benzenemethanol-d1, is a deuterium-labeled analog of Benzyl alcohol, intended for research use only.
- Molecular weight of 109.14 and chemical formula of C7H7DO
- Appears as a colorless to light yellow liquid
- Incorporates stable heavy isotopes of hydrogen (deuterium)
- Soluble in DMSO (≥ 175 mg/mL), Ethanol (≥ 100 mg/mL), and water (20 mg/mL with ultrasonication)
- Serves as a tracer in scientific investigations
- Employed as an internal standard for quantitative analysis in techniques such as NMR, GC-MS, and LC-MS
Medchemexpress LLC Brombuterol-d9 | 1353940-55-2 | 99.0% | 1 MG
Brombuterol-d9 is a deuterium labeled Brombuterol. Brombuterol is a β-adrenergic receptor agonist.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Targets β adrenergic receptor
Cayman Chemical Varenicline-d4, Purity: ≥99% deuterated forms (d1-d4), CAS: 2183239-01-0, 1 mg
An internal standard for the quantification of varenicline by GC- or LC-MS
Alkali Scientific Ethanolamine, 1 Liter
Ethanolamine (1L) is an amine-based reagent widely used in laboratory applications that require a primary or secondary amine for various chemical reactions. It is used in the synthesis of surfactants, detergents, and in the preparation of chelating agents. In biochemical and pharmaceutical research, ethanolamine is utilized in the preparation of buffers and as a stabilizer for certain enzymes. Its versatility in organic synthesis makes it a key reagent in chemical laboratories. This 1L bottle is ideal for large-scale experiments and applications, offering a reliable and high-purity source of ethanolamine for use in a wide range of laboratory processes.
Medchemexpress LLC L-Glutamine-15N2 | 204451-48-9 | 148.13 | 5 MG
L-Glutamine-15N2 is the 15N-labeled L-Glutamine, a non-essential amino acid abundant throughout the body and involved in many metabolic processes. It provides a source of carbons for oxidation in some cells. Stable heavy isotopes of elements like carbon and nitrogen are incorporated into molecules, serving as tracers for quantitative analysis during drug development.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Pregn-4-ene-3,20-dione-d9 | 15775-74-3 | MFCD01317491 | 99.7% | 323.52 | C21H21D9O2 | 10 MG
Progesterone-d9 is a deuterium-labeled analogue of the endogenous steroid hormone progesterone, provided as a solid for research use. It is intended for use as a tracer and internal standard in quantitative analytical methods and pharmacokinetic or metabolic studies.
- Deuterium-labeled tracer and internal standard for NMR, GC-MS, and LC-MS.
- Chemical formula C21H21D9O2.
- Molecular weight 323.52 g/mol.
- Supplier-listed purity ~99.7% (verify for critical use).
- Appearance: white to light yellow solid.
- Solubility: DMSO 50 mg/mL; may require sonication and warming.
- Storage: powder at -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- Typical pack size: 10 mg.
Medchemexpress LLC Rivastigmine-d4 tartrate | 129101-54-8 | 404.45 | C18H24D4N2O8 | 1 MG
Rivastigmine-d4 tartrate is a deuterium-labeled analog of rivastigmine tartrate supplied for research use. It is a cholinesterase inhibitor used in studies of neurodegenerative diseases and is suitable as an isotopic internal standard or tracer in analytical and pharmacokinetic workflows.
- Deuterium-labeled for use as an internal standard and tracer in analytical studies.
- Used to study cholinesterase inhibition relevant to Alzheimer's and Parkinson's research.
- Blood-brain barrier permeable analog appropriate for in vitro and in vivo models.
- High solubility in water (approx. 50 mg/mL) facilitates stock solution preparation.
- Provided in a small pack size suitable for discovery and analytical workflows.
- For research use only; not for human or clinical use.
Medchemexpress LLC Imidacloprid-d4 | 1015855-75-0 | 98.9% | 1 MG
Imidacloprid-d4 is a deuterium-labeled form of Imidacloprid, a neonicotinoid pesticide used to control pests in various crops. This compound is intended for research use only. Stable heavy isotopes, like deuterium, are incorporated into drug molecules for use as tracers in drug development, with potential effects on pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
![Revvity Health Sciences Inc Estrone Sulfate, Ammonium Salt-, [6,7-<sup>3</sup>H(N)]-, 250µCi (9.25MBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/509050995.jpg-250.jpg)
Revvity Health Sciences Inc Estrone Sulfate, Ammonium Salt-, [6,7-3H(N)]-, 250µCi (9.25MBq)
Estrone Sulfate, Ammonium Salt-, [6,7-3H(N)]-, 250µCi (9.25MBq)
Medchemexpress LLC Upadacitinib-15N,d2 | 100.0% | 383.37 | C17H17D2F3N515NO | 1mg
Upadacitinib-15N d2 (ABT-494-15N d2) is the deuterium-labeled Upadacitinib (HY-19569) Upadacitinib-15N d2 (ABT-494) is a potent orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50 43 nM) Upadacitinib-15N d2 (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific relevant cytokines Upadacitinib-15N d2 (ABT-494) can be used for several autoimmune disorders research[1][2]
Medchemexpress LLC Metaldehyde-d16 | 1219805-73-8 | 500 UG
Metaldehyde-d16 is a deuterium labeled Metaldehyde. It can be used as a tracer and as an internal standard for quantitative analysis.
- Used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC MCPA-d3 | 352431-14-2 | 98.0% | 5 MG
MCPA-d3 is the deuterium labeled MCPA (HY-B0859). MCPA is an orally active phenoxyacetic acid herbicide that interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. It also increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA can be used to control broadleaf weeds.
- Application as a tracer.
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, primarily as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Pitavastatin-d4 | 2070009-71-9 | 98.8% | 5 MG
Pitavastatin-d4 is a deuterium-labeled form of Pitavastatin, a potent HMG-CoA reductase inhibitor. It is effective in inhibiting cholesterol synthesis and acts as an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer.
- Deuterium-labeled compound
- Potent HMG-CoA reductase inhibitor
- Inhibits cholesterol synthesis from acetic acid
- Efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer
- Possesses anti-atherosclerotic effects
- Possesses anti-asthmatic and anti-osteoarthritis effects
- Exhibits antineoplastic, neuroprotective, hepatoprotective, and reno-protective effects