Isotopically Labeled Compounds
Medchemexpress LLC Linalool-d3 | 1216673-02-7 | 157.27 | 5 MG
Linalool-d3 is the deuterium-labeled version of Linalool, a natural monoterpene found in essential oils of coriander. It acts as a competitive antagonist of the N-methyl d-aspartate (NMDA) receptor, exhibiting anti-tumor and anti-cardiotoxicity activities. It also functions as a PPARα ligand, reducing plasma TG levels and altering hepatic transcriptome and plasma metabolome.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cambridge Isotope Laboratories PREGNENOLONE SULFATE, SODIUM SALT (20,21-13C2, 99%;16,16-D2, 98%), 5 MG
PREGNENOLONE SULFATE, SODIUM SALT (20,21-13C2, 99%;16,16-D2, 98%), 5 MG
Cambridge Isotope Laboratories SPECTRA 9 (D, 97%+; 15N, 98%+), 0.5 L
SPECTRA 9 (D, 97%+; 15N, 98%+), 0.5 L
Medchemexpress LLC Benzophenone-d10 | 22583-75-1 | MFCD00143675 | 99.6% | 192.28 g·mol⁻1 | C13D10O | 100mg
Benzophenone-d10 is the deuterium labeled Benzophenone (HY-Y0546) Benzophenone is an endogenous metabolite Benzophenone is a photosensitizer that absorbs UV light transfers its energy to DNA and triggers DNA damage Benzophenone can be used as the fragrance enhancer ultraviolet curing agent additive in plastics or the flavor ingredient Benzophenone can also be used in the manufacturing of insecticides agricultural chemicals hypnotics antihistamines and other pharmaceuticals Benzophenone exhibits certain carcinogenicity in mouse/rat models under long term exposure Benzophenone exhibits estrogenic activity[1][2]
Medchemexpress LLC (rel)-Lopinavir-d8 ((rel)-ABT-378-d8) | 1322625-54-6 | C37H40D8N4O5 | 1 MG
(rel)-Lopinavir-d8 ((rel)-ABT-378-d8) is the deuterium-labeled version of Lopinavir. Lopinavir is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. It acts by arresting the maturation of HIV-1, thus blocking its infectivity. Lopinavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 14.2 μM. This product is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC D-Fructose-d | 374089-83-5 | 1 MG
D-Fructose-d is the deuterium labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
- Metabolism-protein/nucleotide metabolism
Medchemexpress LLC HEPES-d18 | 203805-87-2 | 99.9% | 5 MG
HEPES-d18 is the deuterium-labeled HEPES. HEPES, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is also a potent inducer of lysosome biogenesis. For research use only.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Letrozole-d4 | 1133712-96-5 | 99.23% | C17H7D4N5 | 1 MG
Letrozole-d4 (CGS 20267-d4) is a deuterium-labeled version of Letrozole. Letrozole (CGS 20267) is described as a potent, selective, reversible, and orally active non-steroidal inhibitor of aromatase, with an IC50 of 11.5 nM. It selectively inhibits estrogen biosynthesis and is used in breast cancer research.
- Deuterium labeled compound.
- Potent, selective, reversible, and orally active non-steroidal aromatase inhibitor.
- IC50 of 11.5 nM against aromatase.
- Selectively inhibits estrogen biosynthesis.
- Useful for breast cancer research.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Prazosin-d8 | 1006717-55-0 | 98.0% | 1 MG
Prazosin-d8 is a deuterium-labeled analog of Prazosin. It acts as an alpha-adrenergic blocker and is a sympatholytic drug primarily used for the treatment of high blood pressure, anxiety, PTSD, and panic disorder.
- Deuterium labeled Prazosin
- Functions as an alpha-adrenergic blocker
- Sympatholytic drug
- Used to treat high blood pressure, anxiety, PTSD, and panic disorder
- Can be utilized as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration may influence pharmacokinetic and metabolic profiles
Cambridge Isotope Laboratories (RS)-2-HYDROXYGLUTARIC ACID, DISODIUM SALT (2,3,3-D3; OD, 98%) CP 95%, 0.1 G
(RS)-2-HYDROXYGLUTARIC ACID, DISODIUM SALT (2,3,3-D3; OD, 98%) CP 95%, 0.1 G
Cayman Chemical Doripenem-d4 (sodium salt), Purity: ≥99% deuterated forms (d1-d4), 1 mg
An internal standard for the quantification of doripenem by GC- or LC-MS
Medchemexpress LLC Octacosane-d58 | 16416-33-4 | MFCD00190493 | 99.1% | 453.12 g/mol | C28D58 | 10 MG
Octacosane-d58 is the deuterium-labeled analogue of octacosane provided as a white to off-white solid for analytical and research applications. It is intended as a stable-isotope internal standard and tracer for mass spectrometry and chromatography, enabling reliable quantitation and method development in lipidomics and related workflows.
- High isotopic labeling and overall purity: 99.1%.
- Molecular formula C28D58 and molecular weight 453.12 g/mol.
- Solid, white to off-white appearance for easy handling and storage.
- Suitable as a mass spectrometry internal standard and tracer in quantitative analyses.
- Available in small, analytical-scale package sizes for method development.
![Revvity Health Sciences Inc ATP, [γ-<sup>32</sup>P]- 6000Ci/mmol 150mCi/ml, 5 mCi](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502812266.jpg-250.jpg)
Revvity Health Sciences Inc ATP, [γ-32P]- 6000Ci/mmol 150mCi/ml, 5 mCi
ATP, [γ-32P]- 6000Ci/mmol 150mCi/ml, 5 mCi
Medchemexpress LLC Chloroxylenol-d6 | 1407521-66-7 | 2.5 MG
Chloroxylenol-d6 is the deuterium-labeled form of Chloroxylenol, a broad-spectrum antimicrobial chemical compound. It is utilized to manage bacteria, algae, fungi, and viruses. This compound is for research use only and serves as a tracer and internal standard in various analytical techniques.
- It is a deuterium labeled Chloroxylenol.
- It exhibits broad-spectrum antimicrobial properties.
- It is effective in controlling bacteria, algae, fungi, and viruses.
- It can be used as a tracer in research applications.
- It serves as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- The incorporation of stable heavy isotopes into drug molecules allows for their use as tracers for quantitation during the drug development process.
- Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Methyl nicotinate-d4 | 345909-99-1 | 99.5% | 5 MG
Methyl nicotinate-d4 is the deuterium labeled Methyl nicotinate, used as an active ingredient as a rubefacient in over-the-counter topical preparations for muscle and joint pain. This compound can be used as a tracer and as an internal standard for quantitative analysis by various methods.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Methyl nicotinate is found in alcoholic beverages
- Applications in muscle and joint pain preparations