Isotopically Labeled Compounds
Medchemexpress LLC Ethylmalonic acid-d3 | 70907-93-6 | 98.0% | 135.13 | 1 MG
Ethylmalonic acid-d3 is the deuterium labeled Ethylmalonic acid. It is a short-chain organic dicarboxylic acid that synergistically induces mitochondrial permeability transition (MP) with Ca2+, inhibits Mi-CK, and disrupts mitochondrial energy metabolism. It can be used in the research of SCADD, EE, and other genetic metabolic diseases characterized by EMA accumulation.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
Cambridge Isotope Laboratories L-TYROSINE (1-13C, 99%), 1 G, 81201-89-0
L-TYROSINE (1-13C, 99%), 1 G, 81201-89-0
Medchemexpress LLC Dimethyl fumarate-d2 | 23057-98-9 | MFCD08704934 | 99.2% | 146.14 g/mol | C6H6D2O4 | 10 MG
Dimethyl fumarate-d2 is the deuterium-labeled isotopologue of dimethyl fumarate provided as a research reference standard. It is used in analytical, pharmacokinetic, and mechanistic studies where a mass-shifted tracer or internal standard is required, enabling precise detection and quantitation by mass spectrometry.
- Deuterium-labeled for mass spectrometry and tracer studies.
- Suitable as an internal standard in analytical and pharmacokinetic assays.
- High chemical purity: 99.2%.
- Available in small research quantities (10 mg) for analytical workflows.
- Molecular formula C6H6D2O4; molecular weight 146.14 g/mol.
Cambridge Isotope Laboratories 2'-DEOXYADENOSINE:H2O (DEOXYRIBOSE-2-13C, 99%), 0.1 G
2'-DEOXYADENOSINE:H2O (DEOXYRIBOSE-2-13C, 99%), 0.1 G
Medchemexpress LLC Benzoic-carboxy-13C acid, 2-methyl- | 70838-82-3 | 99% | 137.14 | 25 MG
o-Toluic acid-13C is the 13C labeled version of o-Toluic acid (2-Methylbenzoic acid), which is a benzoic acid substituted with a methyl group at position 2. It functions as a xenobiotic metabolite. This product is intended for research use only and is not sold to patients.
- 13C labeled o-Toluic acid.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes like 13C can affect the pharmacokinetic and metabolic profiles of drugs.
![Medchemexpress LLC L-alanine-13C2,15N | 312623-85-1 | MFCD34676307 | 99.0% | 92.07 g/mol | C[13C]2H7[15N]O2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000296328.png-250.jpg)
Medchemexpress LLC L-alanine-13C2,15N | 312623-85-1 | MFCD34676307 | 99.0% | 92.07 g/mol | C[13C]2H7[15N]O2 | 10 MG
L-Alanine-13C2,15N is L-alanine labeled with two 13C atoms and one 15N atom, supplied as a high-purity isotopically labeled standard for use in analytical and metabolic studies.
- Isotopically labeled with two 13C and one 15N
- High purity: 99.0%
- Suitable as a tracer and internal standard for NMR, GC-MS, and LC-MS
- Molecular weight: 92.07 g/mol
- Available as a 10 MG vial for analytical use
Medchemexpress LLC Enalapril-d5 (maleate) | 349554-02-5 | 99.0% | 1 MG
Enalapril-d5 (maleate) is deuterium labeled Enalapril, an angiotensin converting enzyme (ACE) inhibitor. Intended for research use only, this compound serves as a valuable tool for quantitative analysis.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Phenelzine-d5 sulfate | 1219798-40-9 | 99.97% | 1 MG
Phenelzine-d5 sulfate is the deuterium labeled version of Phenelzine sulfate, an orally active, irreversible antidepressant agent. It inhibits monoamine oxidase (MAO-A and MAO-B), GABA transaminase, primary amine oxidase (PrAO), and sequesters reactive aldehydes. It also inhibits LSD1 (Ki: 5.6 μM), reduces oxidative stress, lipogenesis, and increases neurotransmitter levels. It is studied for potential in neurological, metabolic, and cancer-related diseases.
- Used as a tracer (deuterium labeled compound).
- Internal standard for quantitative analysis (NMR, GC-MS, LC-MS).
- High purity (99.97%).
- For research use only.
- Potential neuroprotective effects.
- Inhibits multiple enzymes (MAO-A, MAO-B, GABA transaminase, PrAO, LSD1).
- Elevates neurotransmitter levels.
Medchemexpress LLC Estriol-d2 | 53866-32-3 | 98.5% | 500 UG
Estriol-d2 is a deuterium-labeled version of Estriol. It acts as an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells. Intended for research use only, this compound serves as a tracer and internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. Deuteration in drug molecules is utilized for quantitation during development and can impact pharmacokinetic and metabolic profiles.
- Functions as an antagonist of the G-protein coupled estrogen receptor
- Used as a tracer in research
- Serves as an internal standard for quantitative analysis
- Molecular formula: C18H22D2O3
- Molecular weight: 290.39
- Available in powder form
Medchemexpress LLC Alverine-d5 citrate | 1215327-00-6 | 98.5% | 5 MG
Alverine-d5 (citrate) is the deuterium labeled Alverine citrate. Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development
Medchemexpress LLC Nitrendipine-d5 | 2469554-26-3 | 99.8% | 1 MG
Nitrendipine-d5 is a deuterium-labeled version of Nitrendipine, an orally active analog of Nifedipine that functions as a dihydropyridine calcium channel blocker. It has been shown to induce apoptosis and possess antihypertensive effects. Additionally, it can block alcohol and morphine withdrawal symptoms, reduce right ventricular hypertrophy, and alleviate pulmonary vascular changes caused by intermittent hypoxia. It also exhibits anticancer effects on neuroblastoma.
- Application as a tracer
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration can influence the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Ethane-13C2-sulfonic acid, 2-amino- | 70155-54-3 | ≥99.0% | 1 MG
Taurine-13C2 is the 13C-labeled Taurine, a sulfur-containing amino acid and an organic osmolyte crucial for cell volume regulation. It functions as a substrate for bile salt formation and modulates intracellular free calcium concentration, also activating autophagy in adipocytes.
- Intended for research use only
- Can be used as a tracer for quantitative analysis
- Functions as an internal standard for quantitative analysis
- Suitable for NMR, GC-MS, or LC-MS applications
Medchemexpress LLC Cytidine-13C | 201996-57-8 | 99.0% | 25 MG
Cytidine-13C is the 13C labeled Cytidine. Cytidine is a pyrimidine nucleoside and a component of RNA. It is also a precursor of uridine and controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism and catecholamine.
- 13C labeled Cytidine
- Pyrimidine nucleoside
- Component of RNA
- Precursor of uridine
- Controls neuronal-glial glutamate cycling
- Affects cerebral phospholipid metabolism
- Affects catecholamine
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Riboflavin-d3 (Vitamin B2-d3) | 83-88-5 | 99.9% | 5 MG
Riboflavin-d3, also known as Vitamin B2-d3 or E101-d3, is the deuterium labeled form of Riboflavin. Riboflavin is an easily absorbed micronutrient that plays a key role in maintaining health in humans and other animals. This product is intended for research use only.
- Tracer.
- Internal standard for quantitative analysis methods such as NMR, GC-MS, or LC-MS.
- Incorporation of stable heavy isotopes like deuterium into drug molecules for quantitation during drug development.
- Potential to influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC MCPA-d3 | 352431-14-2 | 98.0% | 1 MG
MCPA-d3 is a deuterium-labeled variant of MCPA, which is an orally active phenoxyacetic acid herbicide. This compound disrupts membrane integrity, energy metabolism by decreasing ATP levels, and the redox balance within plant cells. It also elevates hepatic cytochrome P-450 levels and boosts the activities of aniline hydroxylase and 7-ethoxycoumarin O-deethylase. It is effective in managing broadleaf weeds.
- Can be utilized as a tracer.
- Can serve as an internal standard for quantitative analysis through techniques such as NMR, GC-MS, or LC-MS.