Isotopically Labeled Compounds
Medchemexpress LLC Scopolamine-d3 hydrobromide | 1279037-70-5 | 98.01% | 387.28 | 5 MG
Scopolamine-d3 hydrobromide is the deuterium labeled Scopolamine hydrobromide. It is a high-affinity muscarinic antagonist capable of crossing the blood-brain barrier and competitively antagonizes 5-HT3 receptors with an IC50 of 2.09 μM. This compound can induce cognitive and memory deficits in animals and is utilized in research for preventing postoperative nausea and vomiting, motion sickness, and nervous system diseases. Stable heavy isotopes like hydrogen and carbon are incorporated into drug molecules primarily as tracers for quantitation during drug development.
- Serves as a tracer.
- Can be used as an internal standard for quantitative analysis through NMR, GC-MS, or LC-MS.
- Deuteration has potential to influence the pharmacokinetic and metabolic profiles of drugs.
Revvity Health Sciences Inc Chromium-51 Radionuclide, 5mCi (185MBq), Sodium Chromate in Normal Saline (pH 8-10), Steri-packaged
Chromium-51 Radionuclide, 5mCi (185MBq), Sodium Chromate in Normal Saline (pH 8-10), Steri-packaged
Medchemexpress LLC Myristic acid-d27 | 60658-41-5 | 255.54 | 100 MG
Myristic acid-d27 is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils. It is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 4-Pentylphenol-d11 | 1219805-30-7 | 98.3% | 175.31 | 1 MG
4-Pentylphenol-d11 | 1219805-30-7 | 98.3% | 175.31 | 1 MG
Medchemexpress LLC Clemizole-d4 | 442-52-4 | 99.8% | 329.86 | C19H16D4ClN3 | 10 MG
Clemizole-d4 is a deuterium-labeled analogue of clemizole supplied as a high-purity solid for use as an internal standard and tracer in quantitative analytical methods. It is suitable for studies involving histamine H1 receptor activity and for research into HCV replication pathways, and is prepared to support reproducible mass spectrometry and NMR measurements.
- Used as an internal standard and tracer for NMR, GC-MS, and LC-MS analyses.
- High purity (99.82%) suitable for quantitative work.
- Molecular weight 329.86; formula C19H16D4ClN3.
- White to off-white solid with recommended frozen storage for long-term stability.
- Soluble in DMSO at 100 mg/mL; may require warming and sonication.
- Intended for research use only; not for human or diagnostic use.
Medchemexpress LLC (S)-rivastigmine-d6 tartrate | 194930-00-2 | 99.0% | 406.46 | C18H22D6N2O8 | 5 MG
(S)-Rivastigmine-d6 tartrate is the deuterium-labeled form of (S)-rivastigmine tartrate supplied as a solid research standard for use as an analytical tracer, internal standard, or in quantitative studies of cholinesterase inhibition. It is intended for laboratory research and includes recommended storage and solvent guidelines for reliable handling.
- Deuterium-labeled internal standard for quantitative analysis
- High isotopic and chemical purity (99.0%)
- Stable solid with recommended storage at -20°C; in solution store at -80°C for long-term stability
- Soluble in DMF, DMSO, and ethanol at specified concentrations
- Available in small milligram quantities for analytical workflows
Medchemexpress LLC Lurasidone-d8-1 hydrochloride | 367514-88-3 | 537.19 g/mol | C28H29D8ClN4O2S | 1 MG
Lurasidone-d8-1 hydrochloride is a deuterium-labeled analogue of lurasidone hydrochloride supplied as a research-grade reference standard for analytical and metabolic studies. It is intended as an isotopically labeled internal standard for LC-MS/MS, ADME, and bioanalytical method development, and is provided in small-scale quantities for laboratory use. This product is for research use only and not for human or clinical use.
- Deuterium-labeled analogue of lurasidone hydrochloride.
- Suitable as an isotopically labeled internal standard for LC-MS/MS and quantitative analysis.
- Intended for research use only, not for human or clinical use.
- Available in small-scale quantities appropriate for analytical assays.
- Molecular formula: C28H29D8ClN4O2S; molecular weight: 537.19 g/mol.
Medchemexpress LLC Baloxavir acid-d4 | 2415027-80-2 | 99.3% | 487.51 | C24H15D4F2N3O4S | 1mg
Baloxavir-d4 (Baloxavir acid-d4 S-033447-d4) is the deuterium-labeled Baloxavir (HY-109025A) Baloxavir-d4 (Baloxavir-d4 acid) derived from the proagent Baloxavir-d4 marboxil is a first-in-class potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses Baloxavir-d4 inhibits viral RNA transcription and replication and has potently antiviral activity[1][2]
Medchemexpress LLC Megestrol acetate-d3 | 162462-72-8 | 387.53 | 500 UG
Megestrol acetate-d3 is a deuterium-labeled version of Megestrol acetate, a synthetic and orally active progesteronal agent. It is utilized as an appetite stimulant for wasting syndromes and decreases nuclear and cytosol androgen receptors. This compound holds potential for HIV studies and downregulates the autophagic catabolic pathway.
- Effective as an appetite stimulant for wasting syndromes such as cachexia
- Decreases nuclear and cytosol androgen receptors in human BPH tissue
- Potential for HIV study and downregulates the autophagic catabolic pathway
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Resiquimod-d5 (R848-d5) | 2252319-44-9 | 99.8% | 319.41 | 1 MG
Resiquimod-d5 is deuterium labeled Resiquimod, a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α. It can be utilized as a tracer and an internal standard in various analytical methods.
- Used as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Acts as a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist
- Induces upregulation of cytokines such as TNF-α, IL-6 and IFN-α
Medchemexpress LLC L-Tryptophan-d5 | 62595-11-3 | 209.26 | 100 MG
L-Tryptophan-d5 is a deuterium labeled L-Tryptophan, which is an essential amino acid and a precursor of serotonin, melatonin, and vitamin B3. Deuteration of drug molecules has garnered attention for its potential impact on pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes can be incorporated into drug molecules for quantitation during drug development.
Medchemexpress LLC L-Glutamine-13C5,15N2 | 285978-14-5 | 153.09 | 1 MG
L-Glutamine-13C5,15N2 is the 13C- and 15N-labeled L-Glutamine. It is a non-essential amino acid abundantly present throughout the body and involved in many metabolic processes, providing a source of carbons for oxidation in some cells. This product is for research use only.
- 13C- and 15N-labeled L-Glutamine
- Non-essential amino acid
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC L-Leucine-1-13C,15N | 80134-83-4 | 133.16 | 100 MG
L-Leucine-1-13C,15N is a form of L-Leucine that has been labeled with 13C and 15N isotopes. L-Leucine is an essential branched-chain amino acid (BCAA) known to activate the mTOR signaling pathway. This compound is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Purity: 99.93%.
- Appearance: Solid.
- Color: White to off-white.
Medchemexpress LLC L-Tyrosine-d2-1 | 30811-19-9 | 183.20 | 25 MG
L-Tyrosine-d2-1 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
- Deuterium labeled L-Tyrosine.
- L-Tyrosine is a non-essential amino acid.
- Can inhibit citrate synthase activity in the posterior cortex.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.