Isotopically Labeled Compounds
Medchemexpress LLC Ethambutol-d4 | 1129526-19-7 | 98.1% | 1 MG
Ethambutol-d4 is a deuterium-labeled version of Ethambutol, a bacteriostatic antimycobacterial agent. It functions by inhibiting arabinosyl transferases, thereby obstructing the formation of bacterial cell walls. This compound can be utilized as a tracer and as an internal standard for quantitative analysis in various methods.
- Deuterium-labeled ethambutol
- Bacteriostatic antimycobacterial agent
- Inhibits arabinosyl transferases
- Obstructs bacterial cell wall formation
- Suitable for use as a tracer
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC 4,4'-((Pentane-1,5-diyl-1,1,5,5-d4)bis(oxy))dibenzimidamide dihydrochloride | 1276197-32-0 | 98.0% | 1 MG
Pentamidine-d4 dihydrochloride is the deuterium labeled Pentamidine dihydrochloride. It is an antimicrobial agent that interferes with DNA biosynthetics. This product appears as a white to off-white solid with a purity of 98.0% and an isotopic enrichment of 99.2%.
- Deuterium labeled compound
- Antimicrobial agent
- Interferes with DNA biosynthetics
- White to off-white solid
- Purity 98.0%
- Isotopic enrichment 99.2%
- Recommended storage at 4°C, sealed, away from moisture
- Recommended storage in solvent: -80°C for 6 months; -20°C for 1 month
Medchemexpress LLC Rifampicin-d3 | 1262052-36-7 | 95.7% | 1 MG
Rifampicin-d3 is a deuterium labeled form of Rifampicin, a potent and broad-spectrum antibiotic. It exhibits activity against bacterial pathogens and anti-influenza virus activities. This compound is for research use only and not sold to patients.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes incorporated into drug molecules for quantitation
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Acetylcholine-d9 chloride | 344298-95-9 | 99.0% | 1 MG
Acetylcholine-d9 chloride is a deuterium-labeled acetylcholine chloride, which is a potent, BBB-permeable cholinergic agonist. This neurotransmitter modulates the activity of dopaminergic neurons by stimulating nicotinic acetylcholine receptors and inhibits p53 mutant peptide aggregation in vitro. It can be utilized as a tracer or an internal standard for quantitative analysis through techniques like NMR, GC-MS, or LC-MS.
- Deuterium-labeled acetylcholine chloride
- Potent and BBB-permeable cholinergic agonist
- Modulates dopaminergic neuron activity
- Inhibits p53 mutant peptide aggregation in vitro
- Suitable as a tracer or internal standard for quantitative analysis
Medchemexpress LLC Alectinib-d6 | 1616374-19-6 | 98.05% | 1 MG
Alectinib-d6 is deuterium labeled Alectinib, a potent, selective, and orally available ALK inhibitor. It effectively penetrates the central nervous system (CNS) and inhibits ALK F1174L and ALK R1275Q with high potency.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Alverine-d5 citrate | 1215327-00-6 | 98.5% | 1 MG
Alverine-d5 citrate is a deuterium-labeled analog of Alverine citrate, categorized as an isotope-labeled compound. It is a white to off-white solid with a purity of 98.5%. This compound can be used in research as a tracer and an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- White to off-white solid appearance
- Purity of 98.5%
- Utilized as a tracer
- Functions as an internal standard for quantitative analysis
- Suitable for NMR, GC-MS, or LC-MS techniques
- Molecular weight: 478.59
- Chemical formula: C26H30D5NO7
- Isotopic enrichment: 99.6%
- Storage as powder: 3 years at -20°C, 2 years at 4°C
- Storage in solvent: 6 months at -80°C, 1 month at -20°C
Medchemexpress LLC L-aspartic acid-13C4,15N | 202468-27-7 | MFCD00144566 | 98.0% | 138.07 | 13C4H7 15NO4 | 10 MG
L-Aspartic acid-13C4,15N is a stable isotope-labeled form of the amino acid L-aspartic acid used as a reference standard and tracer in analytical, metabolic, and mass spectrometry applications.
- Stable isotope-labeled (13C4, 15N) suitable as an internal standard for LC-MS/MS and quantitative assays.
- High purity; ≥98.0%.
- Molecular weight 138.07 provides consistent mass spectrometric behavior.
- Chemical formula 13C4H7 15NO4 reflects isotopic labeling.
- Supplied in small laboratory quantities for analytical workflows.
Medchemexpress LLC Ketotifen-d3 fumarate | 1795138-23-6 | 99.2% | 50 MG
Ketotifen-d3 (fumarate) is a deuterium-labeled version of Ketotifen fumarate. This compound is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer, utilized for the prevention of asthma attacks.
- Can be used as a tracer.
- Can serve as an internal standard for quantitative analysis through methods like NMR, GC-MS, or LC-MS.
Medchemexpress LLC Sulfamethoxazole-13C6 | 1196157-90-0 | 99.9% | 1 MG
Sulfamethoxazole-13C6 is a 13C labeled Sulfamethoxazole (Ro 4-2130-13C6), which is a sulfonamide antibiotic with widespread antibacterial activity. It inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase.
- Suitable for the study of urinary tract infections (UTIs), prostatitis, and bronchitis.
- Can be used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Probenecid-d14 | 1189657-87-1 | 99.5% | 1 MG
Probenecid-d14 is the deuterium labeled version of Probenecid. Probenecid is recognized as a potent and selective agonist for transient receptor potential vanilloid 2 (TRPV2) channels and has been observed to inhibit pannexin 1 channels. This compound is intended for research use only and can be utilized as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium-labeled version of Probenecid
- Potent and selective agonist for TRPV2 channels
- Inhibits pannexin 1 channels
- Can be used as a tracer for quantitative analysis
- Can be used as an internal standard for quantitative analysis
- Molecular weight: 299.45
- Chemical formula: C13H5D14NO4S
- Appearance: Solid
- Color: White to off-white
- For research use only
Medchemexpress LLC Coenzyme Q10-d9 | 2687960-97-8 | 98.2% | 872.40 | 1 MG
Coenzyme Q10-d9 is the deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Camptothecin-d5 | 1329616-37-6 | 99.6% | 353.38 | 5 MG
Camptothecin-d5 is the deuterium labeled Camptothecin. Camptothecin (CPT), an alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM. It shows strong antineoplastic activity against colorectal, breast, lung, and ovarian cancers, and modulates hypoxia-inducible factor-1α (HIF-1α) activity by altering microRNA (miRNA) expression patterns in human cancer cells.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Estradiol-13C2 (β-estradiol-13C2) | 82938-05-4 | 1 MG
Estradiol-13C2 is the 13C-labeled version of Estradiol, which is a steroid sex hormone crucial for maintaining fertility and secondary sexual characteristics in females. Estradiol also upregulates IL-6 expression via the estrogen receptor β (ERβ) pathway.
- Used as a tracer
- Serves as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS
- It is a 13C-labeled compound, indicating it is a stable isotope
Medchemexpress LLC D-Glucose-d1-4 | 106032-61-5 | 98.0% | 50 MG
D-Glucose-d1-4 is the deuterium labeled D-Glucose, a monosaccharide and important carbohydrate in biology. It serves as a carbohydrate sweetener and plays critical roles in general metabolism, cellular metabolic status, and stress response. This compound is for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes of hydrogen and carbon
- Potential to affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Vilazodone-d8 | 1794789-93-7 | 99.0% | C26H19D8N5O2 | 1 MG
Vilazodone-d8 is a deuterium-labeled vilazodone, which acts as a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist. It can be used as a tracer and internal standard for quantitative analysis.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Targets 5-HT1A Receptor
- Appears as a solid
- Color: white to off-white
- Soluble in H2O: ≥ 0.32 mg/mL (0.71 mM)