Podocalyxin Like, Mouse anti-Human, Clone: PODXL/2185, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP27974920UG

Catalog No. NB010516

Description

Podocalyxin Like Monoclonal specifically detects Podocalyxin Like in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.

Specifications

• Antigen: Podocalyxin Like
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Dilution: Immunohistochemistry 1-2 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array
• Gene Accession No.: O00592
• Gene Symbols: PODXL
• Immunogen: Recombinant fragment of human Podocalyxin Like(around aa 310-447) (exact sequence is proprietary)
• Quantity: 20 μg
• Research Discipline: Cancer, Cell Biology, Cellular Markers, Hematopoietic Stem Cell Markers, Stem Cell Markers
• Gene ID (Entrez): 5420
• Target Species: Human
• Form: Purified

• Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array
• Clone: PODXL/2185
• Conjugate: Unconjugated
• Formulation: 10 mM PBS with 0.05% BSA
• Gene Alias: Gp200MGC138240, PCLP1, PCLP-1, PCLPGCTM-2 antigen, PCpodocalyxin, podocalyxin-like, Podocalyxin-like protein 1
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Podocalyxin Like is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin Like antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
• Content And Storage: Store at 4°C.
• Isotype: IgG1 κ