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Various organic compounds consisting of carbon, hydrogen, and oxygen atoms that are found in foods and living tissues; typically broken down to release energy; includes sugars, sugar alcohols, sugar acids and derivatives, glycosyl compounds, and more.
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D-Mannose is a C-2 superpolymer of glucose, naturally occurring in various plants and fruits, exhibiting both anti-inflammatory and antitumor properties. It is an endogenous metabolite and a carbohydrate that plays a crucial role in human metabolism.
Endogenous metabolite
Carbohydrate involved in human metabolism
Important for glycosylation of specific proteins
Exhibits anti-inflammatory activity
Shows antitumor activity
Supplied as a 10 mM solution in DMSO
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Recombinant human TNF-beta (lymphotoxin-α) produced in HEK293 cells and supplied lyophilized with an N-terminal 6xHis tag for research use. The product corresponds to residues L35-L205 (predicted molecular weight 20.8 kDa), is >95% pure by SDS-PAGE, and is formulated in Tris-HCl/NaCl/trehalose to support stability; freeze aliquots for long-term storage.
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Phenyl β-D-glucopyranoside is a compound isolated from Phellodendron amurense. It demonstrates anti-inflammatory and anti-tumor activities by inhibiting nitric oxide (NO) production and the expression of iNOS and COX-2. Additionally, it impedes the nuclear translocation of NF-κB and the expression of pro-inflammatory cytokines and related genes.
Significantly inhibits the expression of inflammatory factors (IL-1β, TNF-α, IL-6, COX-2, CXCL1, MCP-1) induced by LPS in Raw 264.7 cells.
Concentration-dependently inhibits MMP-2 and MMP-9 enzyme activity and Ninj1 expression in Raw 264.7 cells.
Inhibits adhesion to fibronectin, type I collagen, laminin, and gelatin in Raw 264.7 cells.
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In its proprotein form the TGF beta-1/TGFB1 protein serves as a precursor to latency-associated peptide (LAP) and active transforming growth factor beta-1 (TGF-beta-1) chains Critical to maintaining the latent state of TGF- -1 within the extracellular matrix preprotein interacts with environmental molecules such as LTBP1 LRRC32/GARP and LRRC33/NRROS to regulate TGF- -1 activation Animal-Free TGF beta 1/TGFB1 Protein Mouse/Rat (His) is the recombinant mouse-derived animal-FreeTGF beta 1/TGFB1 protein expressed by E coli with C-His labeled tag This product is for cell culture use only
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