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UCL-TRO-1938 is a potent allosteric activator of PI3Kα with an EC50 value of approximately 60 μM. UCL-TRO-1938 can induce cell proliferation and has cardioprotective and neural regeneration effects.
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An oxysterol; inhibits the proliferation of HGC-27 cells at 1 µM, an effect that can be enhanced by knockdown of LXRβ; tumor levels are increased in patients with gastric cancer
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α-Cholestane-d4 is a deuterium-labeled analogue of α-cholestane used as a stable isotope internal standard and tracer in analytical workflows. It supports accurate quantitation, method development, and tracer studies in mass spectrometry and isotope-dilution assays, with high isotopic and chemical purity for reliable results.
Deuterium-labeled internal standard for mass spectrometry
High isotopic and chemical purity for accurate quantitation
Suitable for isotope-dilution assays and tracer studies
Available in small pack sizes for analytical use
Molecular formula C27H44D4 and CAS 205529-74-4 for identification
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TRO 19622 (CAS 22033-87-0) also known as Olesoxime is a cholesterol-like small molecule that modulates mitochondrial function contributing to cellular resilience under stress conditions Preclinical studies demonstrate that TRO 19622 attenuates neurodegeneration supports nerve function and facilitates neuroregeneration following traumatic nerve injury in both in vitro and in vivo models This compound is utilized in research exploring neuroprotection and mechanisms underlying neuronal survival with potential applications in models of neurodegenerative diseases and peripheral nerve trauma
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Resolvin D2 is a metabolite derived from docosahexaenoic acid (DHA) that exhibits anti-inflammatory and anti-infective properties. It acts as a potent regulator of leukocytes and is effective in controlling microbial sepsis. This compound also functions as a remarkably potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons.
Anti-inflammatory activities
Anti-infective activities
Leukocyte regulation
Control of microbial sepsis
TRPV1 and TRPA1 inhibition
Resolution of inflammation and tissue regeneration
Decreases leukocyte:endothelial interactions
Inhibits inflammatory pain
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More