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Betaine-d3 (chloride) is a deuterium-labeled version of Betaine chloride. It is intended for research use only and not for sale to patients. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules primarily as tracers for quantitative analysis during drug development, and deuterium substitution can influence the pharmacokinetic and metabolic profiles of drugs.
Deuterium labeled Betaine chloride.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Purity: 98.63%.
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Ramelteon-d3 (TAK-375-d3) is a deuterium-labelled Ramelteon, a potent and highly selective agonist of MT1/MT2 receptors. It has potential for insomnia research, consistently reducing sleep onset without residual effects or withdrawal symptoms. This compound can be used as a tracer and as an internal standard for quantitative analysis, with deuteration potentially affecting pharmacokinetic and metabolic profiles of drugs.
Deuterium-labelled Ramelteon
Agonist of MT1/MT2 receptors
Reduces sleep onset without residual effects
Can be used as a tracer
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Dopamine D2 receptor agonist-3 is a research compound characterized as a selective D2 receptor partial agonist and a D3 receptor antagonist. In vitro activity is reported with pEC50 8.3 at D2 and <5.5 at D3. In vivo, a 3 mg/kg (s.c.) dose demonstrated high brain penetration (brain:blood ratio ≈5.5) with Tmax ≈0.5 h. The compound is a solid with reported purity of 98.3% and molecular formula C15H22ClN3O.
Selective D2 receptor partial agonist and D3 receptor antagonist.
Reported pEC50 values: 8.3 (D2) and <5.5 (D3).
High reported purity (98.3%).
Solid form, suitable for research applications.
Demonstrated brain penetration in vivo (3 mg/kg, s.c.; brain:blood ratio ~5.5).
Available in small pack sizes, including 25 mg.
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2-Methylanisole-d3 is the deuterium-labeled analogue of 2-methylanisole supplied as a liquid isotopic reagent for synthetic chemistry and analytical applications. It is used as an internal standard in mass spectrometry and as a deuterated intermediate in the preparation of labeled compounds.
Contains three deuterium atoms for isotopic labeling (molecular formula C8H7D3O).
Molecular weight 125.18 g·mol⁻¹.
Useful as an internal standard in mass spectrometry and quantitative analyses.
Serves as a deuterated intermediate for synthesis of labeled compounds.
Appearance: light brown to brown liquid; supplier documentation reports isotopic enrichment and chemical purity.
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A synthetic prodrug which is converted to the vitamin D receptor agonist 1,25-dihydroxy vitamin D3 in vivo; suppresses the synthesis and secretion of parathyroid hormone in secondary hyperparathyroidism; supports bone growth; provides renal and cardiovascular protection during chronic kidney disease
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