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C22-Ceramide (N-Behenoyl-D-erythro-sphingosine) is an endogenous bioactive sphingolipid used in research on membrane dynamics and mitochondrial ceramide channel formation. It reduces the propensity of C16-ceramide channel formation in isolated rat liver mitochondria and in liposomes. Supplied as a solid white to off-white powder with high purity for analytical and biological studies.
Endogenous bioactive sphingolipid relevant to membrane and apoptosis studies.
Reduces propensity of C16-ceramide channel formation in mitochondria and liposomes.
White to off-white solid suitable for handling and formulation.
Purity 98.0% for reproducible experimental results.
Molecular formula C40H79NO3; molecular weight 622.06 g/mol.
Soluble in ethanol and DMF using ultrasonic and warming up to 60°C as needed.
Store at 4°C protected from light; in solution keep at -80°C (up to 6 months) or -20°C (up to 1 month).
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A colorimetric substrate for lipases; converted into p-nitrophenoxide, which can be monitored using UV-Vis spectrophotometry at 400 nm to quantify lipase activity
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