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Norethisterone enanthate is a long-acting parenteral progestogen. It is orally active and functions as a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups. This product is for research use only and not sold to patients.
Long-acting parenteral progestogen
Orally active
Functions as a click chemistry reagent
Contains an alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc)
Can be used as an intramuscular contraceptive agent (in vitro)
Inhibits fertility in female rats (in vivo)
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Medroxyprogesterone is a synthetic human variant of progesterone that acts as a progesterone receptor agonist with oral activity. It can induce cell proliferation through the PI3K/Akt signaling pathway and has an inhibitory effect on atherosclerosis in mice.
Acts as a progesterone receptor agonist with oral activity.
Induces cell proliferation through the PI3K/Akt signaling pathway.
Has an inhibitory effect on atherosclerosis in mice.
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Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. It can be used for the research of osteoporosis. Bazedoxifene acetate also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer.
Medroxyprogesterone acetate (MPA) is a synthetic steroidal derivative structurally related to the endogenous hormone progesterone classified as a progestin Acting primarily through binding to progesterone receptors it modulates gene transcription influencing endometrial proliferation and reproductive pathways Additionally MPA exhibits affinity toward glucocorticoid receptors which may contribute to its physiological effects In biomedical research MPA serves as a standard experimental tool to investigate progesterone receptor signaling mechanisms and steroid hormone interactions Furthermore it is widely used in studies focused on reproductive biology contraceptive mechanisms hormone replacement therapy models oncology research involving hormone-responsive tumors and conditions such as endometriosis
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Resolvin D2 is a metabolite derived from docosahexaenoic acid (DHA) that exhibits anti-inflammatory and anti-infective properties. It acts as a potent regulator of leukocytes and is effective in controlling microbial sepsis. This compound also functions as a remarkably potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons.
Anti-inflammatory activities
Anti-infective activities
Leukocyte regulation
Control of microbial sepsis
TRPV1 and TRPA1 inhibition
Resolution of inflammation and tissue regeneration
Decreases leukocyte:endothelial interactions
Inhibits inflammatory pain
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Cinnamoylglycine-2,2-d2 is a chemical compound with the molecular formula C11H9D2NO3 and CAS number 1219806-46-8. It exhibits a purity of 99.4% by HPLC and appears as a white to off-white solid. This product is intended for research use only.
Consistent with structure by 1H NMR spectrum
Isotopic enrichment of 98.96%
Store as powder at -20°C for 3 years or 4°C for 2 years
Store in solvent at -80°C for 6 months or -20°C for 1 month
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Cyclin D3/CCND3 Antibody (YA484) is a rabbit-derived, non-conjugated IgG monoclonal antibody that targets Cyclin D3/CCND3. This antibody is supplied in 1*TBS (pH 7.4) containing 0.05% BSA and 40% Glycerol, with 0.05% Sodium Azide as a preservative. It is suitable for applications such as Western Blot (WB) and Immunocytochemistry/Immunofluorescence (ICC/IF).
Storage: Stored at -20°C for 1 year; avoid repeated freeze/thaw cycles
Application: WB (1:500-1:1000)
Application: ICC/IF (1:50-1:100)
Background: Functions as a regulatory component of the cyclin D3-CDK4 complex, regulating cell cycle during G(1)/S transition by phosphorylating and inhibiting retinoblastoma protein family members.
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