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Oxytocin acetate (CAS 6233-83-6) is an acetate salt form of oxytocin a neuropeptide synthesized primarily in hypothalamic regions including the paraventricular and supraoptic nuclei Biologically oxytocin acts as a positive allosteric modulator of the -opioid receptor (MOR) enhancing receptor-mediated signaling without directly activating MOR or altering opioid ligand affinity In vitro studies with hMOR-expressing HEK293 cells indicate oxytocin augments signaling induced by MOR agonists such as endomorphin-1 morphine and fentanyl Its intracerebroventricular administration increases neuronal activity in rat nucleus accumbens shell highlighting potential roles in pain modulation social behavior and addiction research
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Resomelagon (AP1189) acetate is a potent, orally active melanocortin receptor (MR) agonist, specific for MC1 and MC3. It induces ERK1/2 phosphorylation and Ca2+ mobilization. Resomelagon acetate also exhibits anti-inflammatory activity and can be used for obesity and chronic inflammation research.
Potent, orally active melanocortin receptor (MR) agonist about MC1 and MC3.
Induces ERK1/2 phosphorylation and Ca2+ mobilization.
Possesses anti-inflammatory activity.
Applicable for obesity and chronic inflammation research.
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Talfirastide acetate is the acetate salt of the endogenous heptapeptide angiotensin-(1-7), used in research on the renin-angiotensin system and studies of cardiovascular, anti-inflammatory, and anti-fibrotic pathways. It is provided as a 10 mM solution (1 mL) or as a powder for reconstitution; sequence is Asp-Arg-Val-Tyr-Ile-His-Pro (DRVYIHP).
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TAT-CBD3A6K acetate is a modified TAT-CBD3 peptide that reduces T- and R-type voltage-dependent calcium currents in dorsal root ganglion (DRG) neurons. It also exhibits anti-nociceptive effects in a model of AIDS-induced peripheral neuropathy by preventing CRMP-2-mediated enhancement of T- and R-type calcium channel function.
Reduces T- and R-type voltage-dependent calcium currents
Exhibits anti-nociceptive effects in AIDS-induced peripheral neuropathy models
Prevents CRMP-2-mediated enhancement of T- and R-type calcium channel function
Modified TAT-CBD3 peptide
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Also available in 1 mL, 1 mg, 2 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Icatibant Acetate, an antagonist of the bradykinin B2 receptor, is used in the treatment of hereditary angioedema. Purity 98%
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TAT-QFNP12 acetate is a peptide that plays a crucial role in cellular signaling pathways. It functions by blocking the NDRG2-PPM1A binding, which in turn reduces Smad2/3 phosphorylation. This peptide is also known to decrease astrocytic MMP-9 production and mitigate blood-brain barrier (BBB) disruption following subarachnoid hemorrhage (SAH).
Blocks NDRG2-PPM1A binding
Reduces Smad2/3 phosphorylation
Decreases astrocytic MMP-9 production
Mitigates blood-brain barrier (BBB) disruption after subarachnoid hemorrhage (SAH)
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Bpc 157 acetate is the acetate salt form of the 15-amino-acid gastric pentadecapeptide BPC-157 supplied for research use. It is provided as a lyophilized peptide for use in in vitro and in vivo experimental studies, with reported wound healing and neuroprotective activities.
Lyophilized peptide suitable for laboratory use.
High purity: 99.8%.
Molecular weight: 1419.54 (free acid).
Available in small research sizes, e.g., 10 mg.
RP-HPLC documentation available for purity verification.
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Protirelin acetate is a highly conserved neuropeptide that plays a crucial role in the hormonal regulation of thyroid-stimulating hormone (TSH) levels, in addition to exhibiting neuromodulatory functions. It is an evolutionarily ancient neuropeptide, with origins predating the divergence of protostomes and deuterostomes, and may have historically been involved in controlling postembryonic growth and reproduction.
Investigated for its effect on body temperature in rats.
Causes a temporary, dose-dependent rise in body temperature in male Wistar rats.
The hyperthermic action may involve the release of thyroid hormone.
Thyroidectomized rats do not show a rise in body temperature when administered Protirelin.
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Histrelin acetate is a GnRH analogue and a GnRH Receptor agonist. It increases serum luteinising hormone (LH), follicle stimulating hormone (FSH), and testosterone levels. It can be used in the research of prostate cancer and endometriosis.
Stimulates release of vasopressin (VP) from isolated rat hypothalamo-neurohypophysial explants
Stimulates oxytocin (OT) release from the rat hypothalamo-neurohypophysial system
Rescues circulating LH concentrations in Csfmop/Csfmop mice
Reduces the number of endometrial glands and atrophies the stroma in rabbits
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Temporin B acetate is an antimicrobial peptide with a molecular weight of 1511.89 and a purity of 99.0%. It is primarily active against Gram-positive bacteria and demonstrates less activity against Gram-negative bacteria.
Antimicrobial peptide
Primarily active against Gram-positive bacteria
Less active against Gram-negative bacteria
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Alisol C 23-acetate is a natural product extracted from Alisma orinentale, which can significantly and strongly inhibit DTH response after oral administration.
Natural product
Extracted from Alisma orinentale
Significantly and strongly inhibits DTH response after oral administration
For research use only
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BIO-11006 acetate is the acetate salt of BIO-11006, an analog of the MANS peptide that inhibits MARCKS (myristoylated alanine-rich C kinase substrate). Supplied for laboratory research use only, the peptide salt is provided with characterization data to support in vitro studies of MARCKS-related signaling and membrane interactions.
High purity suitable for research (>99.9%).
Acetate salt form for improved handling and stability.
Relevant for in vitro studies of MARCKS-mediated signaling and peptide-membrane interactions.
Available in laboratory-scale pack sizes to support assay development.
Characterized molecular weight and formula provided for experimental planning.
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Acetate kinase (ACK) is an enzyme widely distributed in bacteria and archaea. In the presence of ATP and divalent cations, it catalyzes the phosphorylation of acetate and promotes the production of acetyl-CoA. This product, expressed by recombinant Escherichia coli, is often used in biochemical research.
Catalyzes phosphorylation of acetate
Promotes the production of acetyl-CoA
Expressed by recombinant Escherichia coli with an N-terminal His-tag
Molecular weight of 45 kDa
Buffer components: 20 mM Tris-HCl, pH 7.5, 10% glycerol
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Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor that blocks the conversion of farnesyl diphosphate (FPP) to squalene in the cholesterol biosynthesis pathway. It is effective at lowering low-density lipoprotein cholesterol and is used for hypercholesterolemia and mevalonate kinase deficiency (MKD) research.
Squalene synthase inhibitor
Blocks conversion of farnesyl diphosphate (FPP) to squalene
Lowers low-density lipoprotein cholesterol
Used for hypercholesterolemia research
Used for mevalonate kinase deficiency (MKD) research
Solid appearance, white to off-white color
Powder storage: -20°C for 3 years
In solvent storage: -80°C for 6 months, -20°C for 1 month
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