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Filtered Search Results
Alkali Scientific EDTA Disodium Salt [Ethylenediaminetetra acetic acid, disodium salt dihydrate], 10 Kg
EDTA Disodium Salt (10 kg) is a highly concentrated chelating agent used for a variety of laboratory applications. Its ability to sequester metal ions makes it essential in preventing metal ion catalysis and ensuring accurate results in chemical reactions. This 10 kg bulk package is commonly used in molecular biology, biochemistry, and microbiology laboratories. EDTA effectively inhibits enzymes that require metal ions as cofactors, preventing undesired reactions during sample preparation, analysis, and preservation. This large volume is perfect for laboratories requiring frequent use of chelating agents in large-scale experiments or industrial applications, where controlling the concentration of metal ions is critical.
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Medchemexpress LLC K-Ras ligand-Linker Conjugate 6 | 2378261-89-1 | 100 MG
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K-Ras ligand-Linker Conjugate 6 is a chemical compound with the formula C42H60N8O7 and a molecular weight of 788.98. This product appears as an oil and is stable under recommended storage conditions. It is intended for use as a laboratory chemical and for the manufacture of substances, strictly for research purposes by experienced personnel in appropriately equipped facilities.
- Identified for laboratory chemical applications
- Chemical formula: C42H60N8O7
- Molecular weight: 788.98
- Physical appearance: oil
- Stable under recommended storage conditions
- May cause skin and serious eye irritation
- May cause respiratory irritation
- Harmful if swallowed
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Medchemexpress LLC Retagliptin (phosphate) | 1256756-88-3 | 99.7% | 562.36 | 1 ML
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Retagliptin phosphate (SP2086 phosphate) is a selective, competitive and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. Retagliptin phosphate can be used for type 2 diabetes mellitus (T2DM) research.
- Selective, competitive, and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor.
- Can be used for type 2 diabetes mellitus (T2DM) research.
- Inhibits the degradation of GLP-1, amplifying the incretin effect.
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Medchemexpress LLC Cyclic GMP-AMP (disodium); 3',3'-cGAMP (disodium) | 2407516-83-8 | 98.47% | 718.37 | 1 MG
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cGAMP disodium is an endogenous second messenger that triggers interferon production in response to cytosolic DNA. It activates stimulator of interferon genes (STING), leading to a signaling cascade that produces type I interferons and other immune mediators. This product is suitable for various research applications.
- Promotes antigen-specific proliferation capacity of spleen cells
- Directly activates murine and human dendritic cells in vitro
- Increases transcription of IFNB1 in stimulated fibroblasts
- Induces an antiviral state and type I IFN secretion by activating ER-resident receptor STING
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Apexbio Technology LLC Pamidronate Disodium 57248-88-1 50mg
Pamidronate Disodium (CAS 57248-88-1) is a small-molecule inhibitor targeting osteoclastic bone resorption It is designed to inhibit osteoclast-mediated bone degradation thereby regulating bone metabolism Pamidronate Disodium exerts its biological activity primarily through selective binding to hydroxyapatite crystals in bone followed by suppression of osteoclast activity and induction of osteoclast apoptosis In in vitro studies Pamidronate Disodium demonstrates inhibitory activity on osteoclastic bone resorption with an IC50 in the micromolar range (varying according to experimental conditions) Based on these pharmacological properties Pamidronate Disodium holds research potential in studies of bone density disorders osteoporosis hypercalcemia of malignancy and metastatic bone diseases
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Apexbio Technology LLC Clodronate Disodium 22560-50-5 50mg
Clodronate Disodium is a synthetic bisphosphonate designed to inhibit osteoclast-mediated bone resorption thereby interfering with bone remodeling processes Clodronate Disodium exerts its biological activity primarily by inducing apoptosis of osteoclasts and hindering their formation and function Liposome-encapsulated Clodronate Disodium formulations are also used experimentally to selectively deplete macrophages in vivo Based on these pharmacological properties Clodronate Disodium holds research potential in studies of osteoclast biology bone metabolic pathways osteoporosis metastatic bone disease arthritis and in investigating macrophage-mediated inflammatory and autoimmune responses as well as tumor-associated macrophage functions
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TARGETMOL CHEMICALS INC Transcrocetinate disodium 10MG
Also available in 1 mL, 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Transcrocetinate disodium (Disodium trans-crocetinate), extracted from saffron (Crocus sativus L.), is a high-affinity antagonist of NMDA receptor. Purity 99.22%
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Medchemexpress LLC ERRα Ligand-Linker Conjugates 1 | 98.8% | 50 MG
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ERRα Ligand-Linker Conjugates 1 incorporates a ligand for estrogen-related receptor alpha (ERRα), and a PROTAC linker, which recruit E3 ligases MDM2. It can be used in the synthesis of a series of PROTACs, such as PROTAC ERRalpha Degrader-1. This product is for research use only.
- Incorporates a ligand for estrogen-related receptor alpha (ERRα)
- Includes a PROTAC linker
- Recruits E3 ligases MDM2
- Can be used in the synthesis of PROTACs
- For research use only
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Apexbio Technology LLC Pamidronate Disodium 57248-88-1 10mM (in 1mL H2O)
Pamidronate Disodium (CAS 57248-88-1) is a small-molecule inhibitor targeting osteoclastic bone resorption It is designed to inhibit osteoclast-mediated bone degradation thereby regulating bone metabolism Pamidronate Disodium exerts its biological activity primarily through selective binding to hydroxyapatite crystals in bone followed by suppression of osteoclast activity and induction of osteoclast apoptosis In in vitro studies Pamidronate Disodium demonstrates inhibitory activity on osteoclastic bone resorption with an IC50 in the micromolar range (varying according to experimental conditions) Based on these pharmacological properties Pamidronate Disodium holds research potential in studies of bone density disorders osteoporosis hypercalcemia of malignancy and metastatic bone diseases
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Alkali Scientific EDTA Disodium Salt [Ethylenediaminetetra acetic acid, disodium salt dihydrate], 2.5 Kg
EDTA Disodium Salt (2.5 kg) is a high-concentration chelating agent used for laboratory experiments that require the removal or sequestration of metal ions. This 2.5 kg package is ideal for large-scale applications in biochemistry, molecular biology, and other scientific fields where metal ion control is essential. EDTA works by binding to metal ions such as calcium, magnesium, and iron, preventing them from catalyzing unwanted chemical reactions or interfering with enzymatic activity. It is widely used in DNA and RNA extraction, enzyme assays, and metal ion quantification. Laboratories that conduct frequent experiments requiring consistent metal ion control benefit from this bulk packaging.
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Medchemexpress LLC ADP-ribose-pNP disodium | 00-00-0 | 99.9% | 724.37 g/mol | C21H24N6Na2O16P2 | 5 MG
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pNP-ADPr disodium is a colorimetric ADP-ribose p-nitrophenyl substrate used to measure poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3) activity. It is supplied in small research pack sizes for enzymatic assays and enables continuous colorimetric monitoring of hydrolase activity.
- Colorimetric substrate for poly(ADP-ribose) glycohydrolase (PARG) and ARH3 assays.
- Enables the first continuous colorimetric assay format for PARG activity.
- Suitable for kinetic and end-point enzymatic assays.
- Supplied as the disodium salt for improved aqueous solubility.
- Available in small research pack sizes (1 mg, 5 mg, 10 mg).
- High analytical purity (~99.9%).
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Medchemexpress LLC Sitagliptin phosphate monohydrate | 654671-77-9 | MFCD10001393 | 523.32 | 1 G
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Sitagliptin phosphate monohydrate | 654671-77-9 | MFCD10001393 | 523.32 | 1 G
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Medchemexpress LLC Piperaquine (phosphate) | 85547-56-4 | 98.6% | 25 MG
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Piperaquine phosphate is a bisquinoline antimalarial agent. It can be used in antimalarial research in combination with Artemisinin.
- Bisquinoline antimalarial agent.
- Can be used in antimalarial research in combination with Artemisinin.
- In vivo, Piperaquine (10-90 mg/kg; a single i.p.) decreases parasitemia in mice.
- At a dose of 90 mg/kg, it resulted in stable body weights and active mice throughout the study.
- Purity: 98.62%.
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Apexbio Technology LLC Phosphatase Inhibitor Cocktail (1 Tube, EDTA-Free, 100X)(Synonyms: Phosphatase Inhibitor Cocktail, Phosphatase Inhibitor Mix, Phosphatase Inhibitor Set), 1ml.
Phosphatase Inhibitor Cocktail (1 Tube EDTA-Free 100X) provides comprehensive inhibition of various phosphatases including acid and alkaline phosphatases serine/threonine phosphatases (e g PP1 PP2A PP2B) and protein tyrosine phosphatases (PTPs) By suppressing phosphatase enzymatic activities it preserves phosphorylation states of proteins in lysates from mammalian plant yeast insect or bacterial samples ensuring more accurate downstream analysis It is applicable in protein lysate preparations immunoprecipitations nuclear extracts and processing of fixed tissues (e g FFPE) to maintain phosphorylation modifications
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Medchemexpress LLC Crocetin disodium | 591230-99-8 | 99.3% | 372.37 | 100 MG
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Crocetin (Transcrocetin) disodium is extracted from saffron (Crocus sativus L.) and acts as an NMDA receptor antagonist with high affinity. It is for research use only and not sold to patients.
- Extracted from saffron (Crocus sativus L.).
- Acts as an NMDA receptor antagonist.
- Exhibits high affinity.
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