Sugar acids and derivatives
Medchemexpress LLC 2H-1-benzopyran-2-one, 7-(beta-D-glucopyranosyloxy)-4-methyl- | 18997-57-4 | MFCD00063694 | 99.9% | 338.31 g/mol | C16H18O8 | 10MM 1ML
4-Methylumbelliferyl β-D-glucopyranoside is a coumarin-based fluorogenic substrate used to measure β-glucosidase and related enzyme activities. Enzymatic hydrolysis releases the fluorescent 4-methylumbelliferone (4-MU), which emits near 445-454 nm; excitation is pH-dependent. The product is supplied as a 10 mM solution in DMSO (1 mL) and is suitable for fluorescence-based biochemical assays.
Medchemexpress LLC 4-methylumbelliferyl α-D-galactopyranoside | 38597-12-5 | MFCD00063278 | 99.8% | 338.31 g/mol | C16H18O8 | 1 ML
4-Methylumbelliferyl-α-D-galactopyranoside is a fluorogenic substrate for α-galactosidase that releases 4-methylumbelliferone, producing a fluorescent signal used to measure enzyme activity. The product is supplied as a 10 mM solution in DMSO (1 mL) and is commonly used in biochemical assays and high-throughput screening.
- Supplied as 10 mM in DMSO, 1 mL vial.
- High reported purity (≈99.8%).
- Generates a strong fluorometric signal upon enzymatic cleavage.
- Suitable for α-galactosidase activity assays and screening workflows.
- Available in solution and solid pack sizes for assay flexibility.
Medchemexpress LLC Beta-sitosterol | 83-46-5 | MFCD00003631 | 98.0% | 414.71 g·mol⁻¹ | C29H50O | 10 MG
Beta-sitosterol is a plant-derived phytosterol used as a reference standard and research reagent for studies of cell signaling, inflammation, oxidative stress, and antitumor activity. It is supplied in small quantities suitable for laboratory assays and analytical work.
- Used as a reference standard in biochemical and analytical assays.
- Relevant for studies of inflammation, oxidative stress, and cell signaling.
- High purity provides reproducible experimental results.
- Available in small package sizes suitable for bench-scale experiments.
![Medchemexpress LLC 4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine | 693228-63-6 | MFCD14155805 | 99.1% | 368.46 g·mol⁻¹ | C18H20N6OS | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000241055.png-250.jpg)
Medchemexpress LLC 4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine | 693228-63-6 | MFCD14155805 | 99.1% | 368.46 g·mol⁻¹ | C18H20N6OS | 25 MG
CYC-116 is a small-molecule inhibitor of Aurora A and Aurora B kinases with low-nanomolar inhibitory potency. It is used as a research reagent to investigate mitotic signaling and cell-cycle regulation and is supplied as a purified solid for in vitro studies.
- Potent dual Aurora A and B inhibitor with Ki ≈8-9 nM.
- Suitable for studying mitotic signaling and cell-cycle regulation in vitro.
- High purity (>99.0%) for reliable experimental results.
- Chemical formula C18H20N6OS; molecular weight 368.46 g·mol⁻¹.
- Available in multiple small-quantity pack sizes for laboratory use.
Medchemexpress LLC BET-IN-14 | 2243669-93-2 | C30H37N7O2 | 1 MG
BET-IN-14 is an orally active pan BET inhibitor (IC50: 5.35 nM) exhibiting anti-cancer activity. It shows anti-tumor effects against various cancer cell lines, including MM.1S, Ty-82, MV-4-11, and KG-1 cells, with an average IC50 of 174.7 nM after 72 hours. In vivo, BET-IN-14 inhibits tumor growth in MV-4-11 xenograft models.
- Orally active pan BET inhibitor
- Exhibits anti-cancer activity
- Effective against various cancer cell lines (MM.1S, Ty-82, MV-4-11, KG-1)
- Inhibits tumor growth in xenograft models
![Alkali Scientific MUG [4 Methylumbelliferyl β D glucuronide Trihydrate], 250 Mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660064.jpg-250.jpg)
Alkali Scientific MUG [4 Methylumbelliferyl β D glucuronide Trihydrate], 250 Mg
Methylumbelliferyl β-D Glucuronide Trihydrate, 250 mg is a high-sensitivity biochemical reagent used to study glucuronidase enzyme activity. This fluorogenic substrate is hydrolyzed by glucuronidases, releasing a fluorescent signal that can be measured in enzyme assays. It is widely used in clinical diagnostics, microbiological analysis, and biochemical research to investigate enzyme activity and metabolic pathways. The reagent’s high purity and sensitivity make it suitable for accurate detection of low-level enzyme activity, enabling precise measurements in applications such as genetic studies, microbial enzyme analysis, and diagnostic testing for metabolic conditions.
Medchemexpress LLC Insulin receptor beta antibody (YA341) | Protein A affinity purified | Predicted band size: 156 kDa; Observed band size: 95 kDa | 50 μL
This rabbit-derived, non-conjugated IgG monoclonal antibody targets Insulin Receptor Beta. It is for research use only and suitable for applications such as Western Blot (WB) and Immunocytochemistry/Immunofluorescence (ICC/IF).
- Recombinant, monoclonal antibody
- Species reactivity: Human, Rat
- Immunogen: Synthetic peptide corresponding to Human Insulin Receptor
- Formulated in 1*TBS (pH7.4), 0.05% BSA, and 40% Glycerol
- Preservative: 0.05% Sodium Azide
- Storage at -20°C for 1 year
- Avoid repeated freeze/thaw cycles
Medchemexpress LLC Tert-butyl N-(1H-indol-4-yl)carbamate | 819850-13-0 | MFCD04973303 | 95.0-98.0% | 232.28 g/mol | C13H16N2O2 | 100 MG
tert-Butyl 1H-indol-4-ylcarbamate is a synthetic intermediate used in pharmaceutical and medicinal chemistry research. Supplied as a powder for laboratory use and intended for research use only, it serves as a building block in small-molecule synthesis and related workflows.
- Used as a synthetic intermediate in pharmaceutical synthesis.
- Supplied as a powder suitable for laboratory handling.
- Available in multiple pack sizes, including 100 mg, 250 mg, 500 mg, and 1 g.
- Identified by CAS 819850-13-0 and molecular formula C13H16N2O2.
- Storage: powder stable at -20°C (up to 3 years) or 4°C (up to 2 years).
- Product datasheet available; purity and batch details provided by suppliers.
Medchemexpress LLC 4-methylumbelliferyl α-D-galactopyranoside | 38597-12-5 | MFCD00063278 | >98.0% | 338.31 g·mol⁻¹ | C16H18O8 | 100 MG
4-Methylumbelliferyl-α-D-galactopyranoside is a fluorogenic substrate for α-galactosidase enzymes. Hydrolysis liberates 4-methylumbelliferone, a fluorescent reporter used to quantify enzyme activity in biochemical assays and diagnostics. Supplied as a solid for laboratory use.
- High purity (≥98%) suitable for enzymatic assays.
- Generates a fluorescent product with emission maximum ~445-454 nm.
- pH-dependent excitation maxima for flexible assay conditions (≈330-385 nm).
- Solid form for straightforward handling and storage.
- Suitable for α-galactosidase activity measurements and diagnostic workflows.
![Medchemexpress LLC 2-[[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]amino]benzoic acid | 115610-36-1 | MFCD13554294 | 99.9% | 283.28 g/mol | C16H13NO4 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000229118.png-250.jpg)
Medchemexpress LLC 2-[[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]amino]benzoic acid | 115610-36-1 | MFCD13554294 | 99.9% | 283.28 g/mol | C16H13NO4 | 25 MG
Avenanthramide D is a naturally occurring phenolic acid isolated from Avena sativa L., supplied for research applications investigating inflammation and related biochemical pathways.
- High purity suitable for analytical and biological research (>99.8%).
- Molecular formula C16H13NO4; molecular weight 283.28 g/mol.
- Offered in small laboratory quantities such as 25 MG for convenience in assays.
- Store protected from light at 4°C; in solvent, store at -80°C for long-term stability.
- Applicable to studies of anti-inflammatory activity and phenolic acid biochemistry.
Medchemexpress LLC 4-Methylumbelliferyl | 124223-99-0 | 10MG
4-Methylumbelliferyl 2-acetamido-2-deoxy- -D-galactopyranoside is a fluorogenic substrate for studying the enzymatic activity of -galactosidase 4-Methylumbelliferyl 2-acetamido-2-deoxy- -D-galactopyranoside is used to analyze enzyme activity in various biological samples helping scientists gain insight into the function of the enzyme in vivo 4-Methylumbelliferyl 2-acetamido-2-deoxy- -D-galactopyranoside can also be used to screen potential compounds to inhibit or activate this enzyme
Medchemexpress LLC Mac glucuronide linker-1 | 2222981-71-5 | MFCD32671554 | 96.4% | 897.90 | C42H47N3O17S | 50 MG
MAC glucuronide linker-1 is a cleavable glucuronide-based linker designed for antibody-drug conjugate (ADC) research. It enables enzymatic release of payloads from antibody-payload conjugates, facilitating controlled drug release in ADC development.
- Cleavable glucuronide linker for ADCs.
- Designed for enzymatic payload release by glucuronidase.
- Suitable for antibody-agent conjugations and linker-payload development.
- Reported purity approximately 96.4% and molecular weight 897.90.
- Available in multiple pack sizes, including 50 MG.
Medchemexpress LLC CDK1/Cyc B-IN-1 | 2459916-56-2 | 98.5% | 353.85 | 100 MG
CDK1/Cyc B-IN-1 is a selective inhibitor of the CDK1/Cyc B complex with an IC50 of 97 nM. It induces apoptosis and G2/M cell cycle arrest, demonstrating broad-spectrum cytotoxic action against various cancer cell lines.
- Selective inhibitor of CDK1/Cyc B complex
- Induces apoptosis
- Causes G2/M cell cycle arrest
- Exhibits broad-spectrum cytotoxic action against cancer cell lines
- Available in various quantities
- Recommended storage conditions for powder and in solvent
- Soluble in DMSO
Medchemexpress LLC Chrysosplenol D | 14965-20-9 | MFCD01548059 | 99.9% | 360.31 | 10 MG
Chrysosplenol D is a methoxy flavonoid known for inducing ERK1/2-mediated apoptosis in triple-negative human breast cancer cells. It demonstrates anti-inflammatory properties and moderate antitrypanosomal activities.
- Inhibits cell viability in CaCo2 cells.
- Selectively inhibits viability of TNBC cell lines.
- Induces cell cycle aberrations and apoptosis in breast cancer cells.
- Shows antitrypanosomal activity against T.b. brucei.
- Inhibits tumor growth on chick chorioallantoic membranes.
- Protects against LPS-induced systemic inflammatory response syndrome in mice.
- Inhibits croton oil-induced ear edema in mice.
Selleck Chemical LLC Heparin sodium S1346-1g
Heparin sodium a sulfated polysaccharide belonging to the family of glycosaminoglycans has numerous important biological activities associated with its interaction with diverse proteins Heparin is used as an anticoagulant primarily through its interaction with AT III by enhancing AT-IIImediated inhibition of blood coagulation factors including thrombin and factor Xa Heparin prevents the induction of autophagy