Sugar acids and derivatives
Apexbio Technology LLC MG 149 1243583-85-8 10mg
MG 149 (CAS 1243583-85-8) is a small molecule inhibitor of histone acetyltransferases (HATs) exhibiting selectivity for MYST family members Tip60 and MOF with reported IC50 values of 74 M and 47 M respectively As an alkylsalicylate derivative MG 149 competitively binds to the acetyl-CoA pocket of Tip60 thereby impeding its enzymatic activity In cell-based assays using HeLa nuclear extracts MG 149 inhibited HAT activity displaying more pronounced effects on histone H3 acetylation compared to H4 Additionally transcriptomic analyses indicate that MG 149 modulates p53 and NF- B signaling pathways highlighting its utility in studying epigenetic regulation and signaling in cellular models
Cayman Chemical 13C6-4-NItronIlIn 10mg
An internal standard for the quantification of 4-nitroaniline by GC- or LC-MS
Medchemexpress LLC 4-Methylumbelliferyl | 440.61 | C28H40O4 | 50MG
4-Methylumbelliferyl oleate is a fluorogenic substrate for acid and alkaline lipases 4-Methylumbelliferyl oleate is cleaved by lipases liberating 4-Methylumbelliferyl (Ex/Em 320/450 nm)[1][2]
Medchemexpress LLC Mac glucuronide linker-1 | 2222981-71-5 | MFCD32689543 | 96.4% | 897.90 | C42H47N3O17S | 25 MG
MAC glucuronide linker-1 is a cleavable antibody-drug conjugate (ADC) linker intended for research use, designed to release payloads through glucuronide cleavage under target conditions.
- Cleavable glucuronide-based linker for antibody-drug conjugates.
- Intended for research use only.
- CAS number 2222981-71-5.
- Purity 96.36%.
- Molecular weight 897.90.
- Chemical formula C42H47N3O17S.
- Appearance white to off-white solid.
- Storage: store under nitrogen; in solvent, -80°C for 6 months and -20°C for 1 month.
Medchemexpress LLC Bet bromodomain inhibitor 4 | 2407658-41-5 | ≥98.0% | 518.59 g/mol | C27H31FN8O2 | 10 MG
BET bromodomain inhibitor 4 is a small-molecule inhibitor of BET family bromodomain epigenetic reader domains supplied for research use as a 10 mg powder. It is used in preclinical studies to probe BET-mediated epigenetic regulation and assay bromodomain interactions.
- Inhibits BET bromodomain activity.
- Intended for research use only.
- Supplied as a 10 mg powder for laboratory applications.
- Target: epigenetic reader domain (BET bromodomain).
- CAS number: 2407658-41-5.
- Molecular formula: C27H31FN8O2; molecular weight: 518.59 g/mol.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years).
Medchemexpress LLC 4-methylumbelliferyl α-L-arabinofuranoside | 77471-44-4 | MFCD00057308 | 99.9% | 308.28 | C15H16O7 | 5 MG
4-Methylumbelliferyl α-L-arabinofuranoside is a fluorogenic glycosidase substrate used to measure α-L-arabinofuranosidase activity. Enzymatic hydrolysis releases fluorescent 4-methylumbelliferone, enabling sensitive fluorometric assays in biochemical and enzymology workflows. For research use only.
- Fluorogenic substrate for α-L-arabinofuranosidase assays.
- Produces 4-methylumbelliferone for sensitive fluorometric detection.
- High purity (99.93%) to minimize background signal.
- Molecular weight 308.28 and formula C15H16O7.
- Soluble in DMSO at ≥ 50 mg/mL.
- White to off-white solid with recommended cold storage for stability.
- Supplied in small research pack sizes suitable for assay development.
Medchemexpress LLC Tetrahydrouridine dihydrate | 18771-50-1 | MFCD00063468 | 99.8% | 284.26 g/mol | C9H20N2O8 | 10 MG
Tetrahydrouridine dihydrate is the dihydrated form of tetrahydrouridine, a potent competitive inhibitor of cytidine deaminase (CDA). Supplied as a white to off-white solid for research use, it is used to inhibit cytidine deamination, support studies of DNA/RNA synthesis pathways, and sensitize carcinoma cells to cytidine analog chemotherapeutics such as gemcitabine.
- Potent competitive inhibitor of cytidine deaminase (CDA).
- High purity (≈99.8%) suitable for research applications.
- Dihydrate form; molecular weight 284.26 g/mol.
- White to off-white solid, convenient for analytical and biological assays.
- Stable when stored as powder at -20°C (long-term storage).
- Available in small assay sizes for laboratory use.
Medchemexpress LLC Guaiacylglycerol-bet 500mg
Guaiacylglycerol-beta-guaiacyl ether is a model compound of lignin monomers that can be degraded by Bacillus amyloliquefaciens CotA[1]
Chem-Impex International, Inc. N-Acetylneuraminic acid | 131-48-6 | MFCD00006620 | 1G
N-Acetylneuraminic acid, 131-48-6, MFCD00006620, 1G
![Research Products International Corp NANA [n-Acetylneuraminic acid, Synthetic Sialic Acid], 100 Milligrams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-A10080-0.11.JPG-250.jpg)
Research Products International Corp NANA [n-Acetylneuraminic acid, Synthetic Sialic Acid], 100 Milligrams
Substrate for N-Acetylneuraminic acid aldolase.
Apexbio Technology LLC β-Pompilidotoxin 216064-36-7 25mg
-Pompilidotoxin ( -PMTX CAS 216064-36-7) is a peptide neurotoxin isolated from the venom of the solitary wasp Batozonellus maculifrons Composed of 13 amino acids (C71H124N22O17) -PMTX modulates neuronal excitability by selectively slowing the inactivation of voltage-gated sodium (Na ) channels without affecting cardiac Na channels This action is thought to involve interaction with neurotoxin receptor site 3 on the extracellular surface of neuronal Na channels Compared to -pompilidotoxin -PMTX exhibits greater potency in enhancing synaptic transmission at neuromuscular junctions -PMTX serves as a valuable tool for investigating Na channel kinetics and the molecular mechanisms regulating synaptic transmission
Chem-Impex International, Inc. Mucic acid | 526-99-8 | MFCD00004239 | 100G
Mucic acid, 526-99-8, MFCD00004239, 100G
Selleck Chemical LLC N-Acetylneuraminic acid S4792-25mg
N-Acetylneuraminic acid (Neu5Ac NeuAc Acido aceneuramico Acide aceneuramique Acidium aceneuramicum Sialic acid NANA) is the predominant sialic acid found in mammalian cells Sialic acids are negatively charged monosaccharides attached to the end of sugar chains giving rise to a wide variety of glycoproteins and glycolipids in biological fluids and cell membranes