Sugar acids and derivatives
![Medchemexpress LLC [D-Ala2]-GIP (human) | 444073-04-5 | 98.97% | 4983.60 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC [D-Ala2]-GIP (human) | 444073-04-5 | 98.97% | 4983.60 | 25 MG
[D-Ala2]-GIP (human) is a GIP receptor agonist with an EC50 of 630 pM. It improves glucose tolerance and demonstrates neuroprotective activity in an MPTP-induced Parkinson's disease model. Additionally, it enhances cognitive function and hippocampal synaptic plasticity in obese diabetic rats. This product is suitable for research related to type 2 diabetes, Parkinson's disease, and similar conditions.
- Acts as a GIP receptor agonist with an EC50 of 630 pM
- Improves glucose tolerance by stimulating insulin release
- Demonstrates neuroprotective activity in MPTP-induced Parkinson's disease models
- Enhances cognitive function and hippocampal synaptic plasticity in obese diabetic rats
- Attenuates the behavioral phenotype of Parkinson's disease
- Reverses decline in motor ability and reduces muscle stiffness
- Inhibits the increase of MDA levels in the brain
![Apexbio Technology LLC hemagglutinin precursor (114-122) amide [Influenza A virus] 25mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000095536.png-250.jpg)
Apexbio Technology LLC hemagglutinin precursor (114-122) amide [Influenza A virus] 25mg
Hemagglutinin precursor 114-122 amide is a synthetic peptide fragment derived from the hemagglutinin glycoprotein of Influenza A virus It is designed to present antigenic determinants that facilitate the analysis of peptide-MHC interactions and characterization of influenza-specific immune responses Hemagglutinin precursor 114-122 amide exerts its biological activity primarily by eliciting immune responses against Influenza A virus supporting studies on cytotoxic T-cell reactivity and antigenicity Based on these properties hemagglutinin precursor 114-122 amide holds research potential in immunological assays vaccine antigenicity studies and investigations of antiviral immune responses
Aobchem 1-(3-Ethyl-5-methoxyphenyl)cyclobutanol | 95% | C13H18O2 | 500mg
1-(3-Ethyl-5-methoxyphenyl)cyclobutanol | 95% | C13H18O2 | 500mg
Chem-Impex International, Inc. 5-Bromo-4-chloro-3-indolyl-b-D-glucuronide sodium salt | 129541-41-9 | MFCD00135782 | 250MG
5-Bromo-4-chloro-3-indolyl-b-D-glucuronide sodium salt, 129541-41-9, MFCD00135782, 250MG
Aobchem (3-Chloro-4-methoxyphenyl)(cyclopentyl)methanone | 95% | CAS 1094749-02-6 | C13H15ClO2 | 250mg
(3-Chloro-4-methoxyphenyl)(cyclopentyl)methanone | 95% | CAS 1094749-02-6 | C13H15ClO2 | 250mg
Medchemexpress LLC 4-methylumbelliferyl stearate | 79408-85-8 | MFCD00057311 | 99.0% | 442.63 | C28H42O4 | 1 G
4-Methylumbelliferyl stearate is a fluorogenic enzymatic substrate that liberates the fluorescent reporter 4-methylumbelliferone upon esterase or lipase-mediated hydrolysis. It is provided as a solid (white to off-white) for use in biochemical assays to quantify enzyme activity and screen inhibitors.
- Releases highly fluorescent 4-methylumbelliferone upon hydrolysis.
- Suitable for lipase and esterase activity assays.
- High purity (≈98.96%) for reproducible results.
- Solid, white to off-white appearance for easy handling.
- Long shelf life when stored under recommended conditions.
- Solubility and handling details available on the technical datasheet.
Medchemexpress LLC Integrin alpha 8 bet 5ug
Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 Flag His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-10 His C-Flag labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 Flag His) has molecular weight of 85-140 kDa
Medchemexpress LLC 2,4-D sodium | 2702-72-9 | ≥98.0% | 243.02 | 500 MG
2,4-D sodium (2,4-Dichlorophenoxyacetate) is a selective herbicide effective against broad-leaved weeds. It functions by inducing apoptosis and inhibiting DNA and protein synthesis, thereby disrupting normal plant growth and development. In laboratory studies, it inhibits the viability of A549 and WI38 cells with IC50 values of 126 μM and 115 μM, respectively, and can induce apoptosis by influencing the cell cycle. In vivo studies have also shown toxic effects on the reproductive system of male rats, including reduced organ weights and sperm viability.
- Selective herbicide for broad-leaved weeds.
- Induces apoptosis and inhibits DNA and protein synthesis.
- Inhibits A549 and WI38 cell viability in vitro.
- Affects cell cycle and induces apoptosis.
- Causes reproductive toxicity in male rats.
- Reduces organ weights and sperm viability in vivo.
- Increases FSH and LH levels in vivo.
Medchemexpress LLC 2H-1-Benzopyran-2-one, 7-[(4-O-β-D-glucopyranosyl-ẞ-D-glucopyranosyl)oxy]-4-methyl- | 72626-61-0 | MFCD00063279 | 99.4% | 500.45 | 25 MG
4-Methylumbelliferyl β-D-cellobioside is a fluorescent dye and a substrate for cellulase. With a purity of 99.4%, this compound has a molecular weight of 500.45.
- Functions as a fluorescent dye
- Acts as a substrate for cellulase
- Purity: 99.4%
- Molecular weight: 500.45
- Stable as powder at -20°C for 3 years or 4°C for 2 years
- Stable in solvent at -80°C for 6 months or -20°C for 1 month
Aobchem (2-Chloro-3-methoxyphenyl)(cyclopropyl)methanol | 95% | C11H13ClO2 | 1g
(2-Chloro-3-methoxyphenyl)(cyclopropyl)methanol | 95% | C11H13ClO2 | 1g
Medchemexpress LLC Cathepsin D and E FRET Substrate acetate | 99.8% | 1816.15 | 25 MG
Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate specifically for cathepsins D and E, and not for cathepsins B, H, or L. The cleavage of this substrate occurs at the Phe-Phe amide bond. It serves as a valuable tool for routine assays and mechanistic studies concerning cathepsins E and D.
- Fluorogenic substrate
- Specific for cathepsins D and E
- Does not act on cathepsins B, H, or L
- Cleavage at the Phe-Phe amide bond
- Suitable for routine assays
- Useful for mechanistic studies on cathepsins E and D
Medchemexpress LLC D-Glucuronic acid (Standard) | 6556-12-3 | 25 G
D-Glucuronic acid (Standard) is the analytical standard of D-Glucuronic acid, intended for research and analytical applications. It is a major component of many anti-inflammatory proteoglycans, which can promote embryonic development and inhibit cell aggregation. After being metabolized into ethyl glucuronide, D-Glucuronic acid activates Toll-like receptor 4 (TLR4), causing pain. D-Glucuronic acid and its derivative glucurono-lactone can serve as liver detoxifiers for human health prevention, and its derivatives also possess anti-tumor activity.
- Analytical standard for D-Glucuronic acid
- Intended for research and analytical applications
- Promotes embryonic development and inhibits cell aggregation
- Activates Toll-like receptor 4 (TLR4) when metabolized
- Serves as a liver detoxifier; derivatives possess anti-tumor activity
- Commonly used in HPLC, GC, and MS for research experiments
Medchemexpress LLC Integrin alpha V beta 8 protein, mouse | ≥95.0% | 20UG
Integrin alpha V beta 8 protein (mouse) is a recombinant heterodimer expressed in HEK293 cells with a C-terminal His tag, intended for research use in studies of integrin signaling, ligand binding, and cell adhesion. The product is supplied as a purified protein in defined sizes and is characterized by a reported purity and molecular weight range suitable for biochemical and cell-based assays.
- Recombinant mouse integrin heterodimer suitable for functional assays.
- Produced in HEK293 expression system to preserve mammalian modifications.
- His tag facilitates purification and detection in biochemical workflows.
- High purity supports reliable assay results (≥95.0%).
- Supplied in defined sizes for flexible experimental needs.
- Molecular weight consistent with alpha and beta subunits (80-140 kDa).
Medchemexpress LLC Anti-Mouse Human Mac 10mg | 10mg
Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) is a rat-derived anti-mouse/human Mac-2/Galectin-3 IgG2a monoclonal antibody Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) significantly inhibits IL-6 expression (inhibition rates 34 7% and 55 3%) Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) is often used for immunoprecipitation western blot immunofluorescence and flow cytometry[1][2][3][4]
Medchemexpress LLC D-Dimannuronic acid sodium | 10 MG
D-Dimannuronic acid sodium is an alginate extract derived from brown algae. This compound is primarily used in research to synthesize sulfated polymannuronate (SPMG)-derived oligosaccharides. It is intended for research use only.
- Derived from brown algae
- Used to synthesize sulfated polymannuronate (SPMG)-derived oligosaccharides
- For research use only
- Purity of 99.94%
- Molecular weight of 392.25
- Molecular formula is C12H17NaO13
- Appears as a white to off-white solid
- Soluble in H2O at 125 mg/mL (318.67 mM), requires ultrasonic treatment