Fatty acid esters
Medchemexpress LLC Stearoylcarnitine | 25597-09-5 | 99.9% | 427.66 | 50 MG
Stearoylcarnitine is a fatty ester lipid molecule and an endogenous metabolite. It can act as a PKC inhibitor and accumulates in β cells, leading to arrest of insulin synthesis and energy deficiency in type 2 diabetes mouse models. It also inhibits lecithin cholesterol acyltransferase (LCAT) in rat and rabbit plasma and serves as a metabolomics biomarker for Parkinson's disease. Additionally, it is a less potent inhibitor of GlyT2.
- Functions as an endogenous metabolite.
- Acts as a PKC inhibitor.
- Accumulates in beta cells, impairing insulin synthesis.
- Inhibits lecithin cholesterol acyltransferase (LCAT) in rat and rabbit plasma.
- Serves as a metabolomics biomarker for Parkinson's disease.
- Less potent inhibitor of GlyT2.
- Impairs mitochondrial energy metabolism in MIN6 cells.
- Alters brain acylcarnitine levels in a mouse model of hypoxic-ischemic brain injury.
Medchemexpress LLC L-Hexanoylcarnitine | 22671-29-0 | 99.9% | 259.34 | 10 MG
L-Hexanoylcarnitine is an acylcarnitine and is found to be associated with celiac disease. It is for research use only and not sold to patients.
- Endogenous metabolite
- Associated with celiac disease
- Disease markers
- Endocrine diseases
Medchemexpress LLC Quinolinic acid | 89-00-9 | MFCD00006295 | 100.0% | 167.12 g/mol | C7H5NO4 | 50 MG
Quinolinic acid is provided as an analytical reference standard for laboratory use. Supplied as a white to off-white solid, it serves as a calibration and qualitative or quantitative standard in chromatographic and mass spectrometry analyses.
Medchemexpress LLC 3-O-Methyldopa (standard) | 300-48-1 | 99.9% | 211.22 | 10 MG
3-O-Methyldopa (Standard) is the analytical standard of 3-O-Methyldopa, intended for research and analytical applications. It is a metabolite of L-DOPA, formed by catechol-O-methyltransferase (COMT), and competitively inhibits the pharmacodynamics of l-DOPA and dopamine. The compound is commonly used in qualitative, quantitative, and methodological research experiments.
- Used as an analytical standard
- Suitable for HPLC, GC and MS applications
- Metabolite of L-DOPA
- Competitively inhibits l-DOPA and dopamine pharmacodynamics
Medchemexpress LLC Phorbol 12-myristate 13-acetate | 16561-29-8 | 99.8% | 616.83 | 50 MG
Phorbol 12-myristate 13-acetate (PMA) is a phorbol ester that acts as a dual SphK and protein kinase C (PKC) activator. It also functions as an NF-κB activator and induces differentiation in THP-1 cells. This product is for research use only and has been validated by MedChemExpress to induce differentiation in THP-1 cells.
- Dual SphK and protein kinase C (PKC) activator
- NF-κB activator
- Induces differentiation in THP-1 cells
- For research use only
Medchemexpress LLC Sarsasapogenin | 126-19-2 | 416.64 | 50 MG
Sarsasapogenin is a sapogenin from the Chinese medical herb *Anemarrhena asphodeloides Bunge*, with antidiabetic, anti-oxidative, anticancer, and anti-inflammatory activities.
- Derived from *Anemarrhena asphodeloides Bunge*, a Chinese medical herb.
- Exhibits antidiabetic activity.
- Possesses anti-oxidative properties.
- Demonstrates anticancer activity.
- Has anti-inflammatory activities.
Medchemexpress LLC Succinate/succinate receptor antagonist 1 | 2361972-29-2 | C17H15N3O | 1 ML
Succinate/succinate receptor antagonist 1 is an antagonist of the succinate/succinate receptor. It inhibits the activation of succinate receptor 1 (SUCNR1) and blocks succinate signaling in gingival tissue. This product can be used for the study of periodontal disease, with in vitro studies demonstrating significant SUCNR1 activation inhibition by 10 μM concentrations.
- Inhibits succinate receptor 1 (SUCNR1) activation
- Blocks succinate signaling in gingival tissue
- Suitable for the study of periodontal disease
- White to off-white solid appearance
- Stable under recommended storage conditions
- Recommended storage at 4°C, protected from light (solid)
- Recommended storage at -80°C for 6 months or -20°C for 1 month (in solvent), protected from light
Medchemexpress LLC 2-(3-(4-fluoro-3-pyridin-3-yl-phenyl)-imidazo(1,2-a)pyrimidin-7-yl)-propan-2-ol | 461449-78-5 | 97.0% | 348.37 g·mol⁻1 | C20H17FN4O | 10MG
MRK-623 is an orally active, high-affinity GABAA receptor agonist research compound used to study GABAergic signaling and anxiolytic effects in vitro and in vivo. It is supplied as a white to off-white solid with molecular formula C20H17FN4O and molecular weight 348.37 g·mol⁻1, and is provided in small research pack sizes for biochemical and pharmacological assays.
- Orally active GABAA receptor agonist for GABAergic research.
- High affinity against multiple GABAA subunits with low-nanomolar potency.
- High purity suitable for research (manufacturer COA reported 97.0% by NMR).
- Available in small research quantities, including 10 mg packs.
- White to off-white solid physical form, soluble in appropriate solvents for assays.
- Recommended storage: powder at -20°C or 4°C; store solutions at -80°C for long term.
Cambridge Isotope Laboratories Sodium perfluoro-n-decanoate (PFDA) (13C9 99%) 50 ug/mL in methanol 1 2 mL
Sodium perfluoro-n-decanoate (PFDA) (13C9 99%) 50 ug/mL in methanol 1 2 mL
