Hydrobromides
Medchemexpress LLC Eletriptan hydrobromide | 177834-92-3 | 99.8% | C22H27BrN2O2S | 100 MG
Eletriptan hydrobromide is a 5-HT1B and 5-HT1D receptor agonist with antimigraine activity, exhibiting Ki values of 0.92 nM and 3.14 nM, respectively. It is intended for research use only. In vivo studies have shown that eletriptan hydrobromide dose-dependently reduces carotid blood flow in anesthetized dogs and inhibits dural plasma protein extravasation in anesthetized rats.
- Functions as a 5-HT1B and 5-HT1D receptor agonist.
- Exhibits Ki values of 0.92 nM for 5-HT1B receptor.
- Exhibits Ki values of 3.14 nM for 5-HT1D receptor.
- Dose-dependently reduces carotid blood flow in anesthetized dogs.
- Inhibits dural plasma protein extravasation in anesthetized rats.
- Completely inhibits plasma protein extravasation from the dura mater at 100 μg/kg.
Apexbio Technology LLC SR 95531 hydrobromide 104104-50-9 5mg
SR 95531 hydrobromide (CAS 104104-50-9) also known as Gabazine is a selective competitive antagonist of the GABAA receptor By binding to the GABA recognition site on the receptor it blocks the activation induced by -aminobutyric acid (GABA) Experimental studies report an inhibitory concentration (IC50) of approximately 0 2 M for GABAA receptor-mediated responses Widely utilized in neuroscience research Gabazine is applied to investigate the physiological and pathological roles of GABAA receptor-mediated synaptic transmission neural network modulation and neurotransmitter regulation
Medchemexpress LLC Vortioxetine hydrobromide | 960203-27-4 | C18H23BrN2S | 1 ML
Vortioxetine hydrobromide (Lu AA 21004) is a compound that acts as an antagonist of 5-HT3A and 5-HT7 receptors and an inhibitor of the 5-hydroxytryptamine transporter (SERT). It also functions as a 5-HT1A agonist and a partial 5-HT1B agonist.
- Antagonist of 5-HT3A and 5-HT7 receptors
- Inhibitor of 5-hydroxytryptamine transporter (SERT)
- Agonist of 5-HT1A receptors
- Partial agonist of 5-HT1B receptors
- Increases cell proliferation and survival
- Does not cause cognitive or psychomotor impairment