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Filtered Search Results
Medchemexpress LLC GSK3182571 | 2135595-04-7 | MFCD28137930 | 99.8% | 495.02 | C25H31ClN8O | 10MG
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GSK3182571 is a non-selective, broad-spectrum pan-kinase inhibitor used in research to probe kinase networks and assess off-target effects; it can induce changes in target protein thermostability in cellular assays.
- Pan-kinase inhibitor for kinase network and off-target studies.
- High purity: 99.8%.
- Molecular weight 495.02 g/mol; chemical formula C25H31ClN8O.
- Soluble in DMSO at 100 mg/mL (202.01 mM); use ultrasonication and adjust pH to 4 if required.
- Store powder at -20°C (3 years) or 4°C (2 years); store solutions at -80°C for long-term stability.
- Packaged in small milligram quantities suitable for assay development and biochemical testing.
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Medchemexpress LLC AST5902 trimesylate | 2929417-90-1 | 98.8% | 842.88 | 50 MG
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AST5902 trimesylate is the principal metabolite of Alflutinib (AST2818) both in vitro and in vivo. It exerts antineoplastic activity. Alflutinib is an EGFR inhibitor.
- Principal metabolite of Alflutinib
- Exerts antineoplastic activity
- EGFR inhibitor
- Yellow to orange solid
- Store at 4°C, sealed, away from moisture and light
- In solvent: -80°C for 6 months; -20°C for 1 month
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Medchemexpress LLC N-vanillyldecanamide | 31078-36-1 | MFCD01233545 | 99.9% | 307.43 g·mol⁻¹ | C18H29NO3 | 10 MG
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N-Vanillyldecanamide is a capsaicinoid research chemical (CAS 31078-36-1) isolated from the fruits of Capsicum annuum. It has been reported to reduce the radical length of Lactuca sativa seedlings in a dose-dependent manner. The compound is supplied for laboratory research use with supporting documentation for handling and analysis.
- High purity (99.86%) suitable for analytical and biological studies.
- Molecular formula C18H29NO3 and molecular weight 307.43 g·mol⁻¹.
- Supplied in small laboratory quantities, including a 10 mg pack size.
- Available as a solid and as 10 mM solutions in DMSO for convenience.
- Storage: keep at 4°C and protect from light; in solvent: -80°C (6 months) or -20°C (1 month).
- Typical applications include capsaicinoid activity studies, plant physiology research, and structure-activity investigations.
- Product documentation includes datasheet, COA, and SDS for quality and safety reference.
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Medchemexpress LLC Linzagolix | 935283-04-8 | 99.7% | 508.42 | 50 MG
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Linzagolix is a potent, non-peptide, and orally active GnRH antagonist. It can be used for uterine fibroids, endometriosis, and adenomyosis research. For research use only.
- Potent, non-peptide, and orally active GnRH antagonist
- Used for uterine fibroids, endometriosis, and adenomyosis research
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Medchemexpress LLC Acrylodan | 86636-92-2 | 95.1% | 225.29 g/mol | C15H15NO | 5 MG
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Acrylodan is a thiol-reactive, environment-sensitive fluorescent dye that covalently labels cysteine residues and reports on local dipolarity and conformational dynamics within binding pockets such as Cys34.
- Reacts with thiols to form a covalent fluorescent adduct.
- Sensitive to local dipolarity and protein dynamics.
- Soluble in DMSO at approximately 50 mg/mL; ultrasonic agitation may be required.
- Purity approximately 95.1%; molecular weight 225.29 g/mol.
- Store protected from light; in solution store at -80°C (up to 6 months) or -20°C (up to 1 month).
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Medchemexpress LLC CIL62 | 117593-36-9 | 97.0% | 382.45 | 50 MG
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CIL62 is a caspase-3/7-independent cell death inducer that operates via Necrostatin-1 dependent mechanisms. It exhibits antiproliferative activity against human COLO205, IMR32, and K562 cells.
- Caspase-3/7-independent cell death inducer
- Necrostatin-1 dependent mechanism of action
- Antiproliferative activity against COLO205, IMR32, and K562 cells
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Medchemexpress LLC Xylobiose | 6860-47-5 | 1 MG
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Xylobiose is an orally active Claudin 2/CLDN2 inhibitor and HSP27 inducer that regulates intestinal barrier function and glucose and lipid metabolism. It strengthens intestinal barrier integrity, reduces blood sugar and lipid levels, and mitigates oxidative stress and inflammation. It is used in the study of type 2 diabetes and metabolic syndrome.
- Orally active Claudin 2/CLDN2 inhibitor and HSP27 inducer
- Regulates intestinal barrier function
- Modulates glucose and lipid metabolism
- Reduces intestinal permeability
- Enhances cell protection
- Improves insulin resistance
- Reduces blood sugar and lipid levels
- Decreases oxidative stress and inflammatory response
- Applicable in type 2 diabetes and metabolic syndrome research
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Medchemexpress LLC Ambroxide | 6790-58-5 | 236.39 | 100 MG
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Ambroxide is a naturally occurring terpenoid, known as a key constituent of ambergris. This compound is widely utilized in the manufacture of high-end perfumes to enhance aroma quality and extend fragrance lasting time.
- Naturally occurring terpenoid
- Key constituent of ambergris
- Utilized in high-end perfumes
- Enhances aroma quality
- Extends fragrance lasting time
- High purity (98.0%)
- Appears as a white to off-white solid
- Molecular formula: C16H28O
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Jade Scientific, Inc TETRAHYDROFURAN LAB PLUS 19L
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Tetrahydrofuran Lab Plus 19l. 109-99-9 MFCD00005356
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Chemscene ChemScene | (R)-Tetrahydrofuran-2-yl-methylamine | 10G | CS-W011317 | 0.98 | 7202-43-9| MFCD00192476 | 101.15
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ChemScene | (R)-Tetrahydrofuran-2-yl-methylamine | 10G | CS-W011317 | 0.98 | 7202-43-9| MFCD00192476 | 101.15
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Medchemexpress LLC Rifalazil | 129791-92-0 | 99.6% | 941.07 | C51H64N4O13 | 50 MG
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Rifalazil is a rifamycin-class antibiotic research compound that inhibits bacterial DNA-dependent RNA polymerase by binding the β-subunit. It demonstrates potent activity against a range of pathogens and is provided for research use only.
- Inhibits bacterial RNA polymerase by targeting the β-subunit.
- Exhibits high potency against mycobacteria and gram-positive bacteria.
- Active against Helicobacter pylori, Chlamydia pneumoniae, and Chlamydia trachomatis.
- High purity (~99.6%) suitable for research applications.
- Available as a 50 MG solid package.
- Stable when stored sealed at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
- Intended for research use only.
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Medchemexpress LLC 2,2,2-trifluoro-N-[(1R,2S)-1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-(3-methoxyphenyl)propan-2-yl]acet | 1034148-04-3 | MFCD26142626 | 99.9% | 487.45 | C25H21F4N3O3 | 50 MG
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AZD5423 is a non-steroidal, selective glucocorticoid receptor modulator provided as a research chemical for preclinical pharmacology and inhalation therapy studies. It is supplied for laboratory use only and has documented purity and storage recommendations.
- Non-steroidal selective glucocorticoid receptor modulator for preclinical research.
- High reported purity suitable for analytical and pharmacological studies.
- Molecular formula C25H21F4N3O3 and molecular weight 487.45 g/mol.
- Recommended storage conditions provided to maintain compound stability.
- Available in multiple package sizes to support dose-ranging and formulation work.
- Intended for laboratory research use only, not for clinical or human use.
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Medchemexpress LLC L-745870 hydrochloride | 1173023-36-3 | 99.9% | C18H20Cl2N4 | 10MG
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L-745870 hydrochloride is the hydrochloride salt of a selective dopamine D4 receptor antagonist used in pharmacology research. It is brain-penetrant, orally active, and is employed to investigate D4 receptor activity and related neuropharmacological effects.
- Potent and selective dopamine D4 receptor antagonist (Ki 0.43 nM).
- Brain-penetrant and orally active for in vivo studies.
- High chemical purity suitable for research use (99.9%).
- Available as a solid or as a DMSO solution for flexibility in assays.
- Offered in multiple small-scale package sizes for preclinical experiments.
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Medchemexpress LLC Nelonicline | 1026134-63-3 | 99.8% | 313.42 g/mol | C17H19N3OS | 10 MG
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Nelonicline is an orally active, selective agonist of the α7 nicotinic acetylcholine receptor supplied as a research reagent for preclinical and in vitro studies. It has molecular formula C17H19N3OS and molecular weight 313.42 g/mol. For research use only; not for clinical or diagnostic applications.
- Selective α7 nicotinic acetylcholine receptor agonist suitable for receptor pharmacology studies.
- Orally active small molecule compatible with in vivo and in vitro experiments.
- Available as a 10 MG solid and as a 10 mM solution in DMSO for assay use.
- High-purity research compound appropriate for preclinical studies.
- Supplied for research use only, not intended for therapeutic use.
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Medchemexpress LLC BDP9066 | 2226507-04-4 | 98.2% | 348.44 | 10 MG
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BDP9066 is a potent and selective myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor. It has an IC50 of 64 nM for MRCKβ in SCC12 cells, and Ki values of 0.0136 nM and 0.0233 nM for MRCKα/β respectively. It demonstrates a therapeutic effect on skin cancer by reducing substrate phosphorylation. This product is for research use only.
- Targets MRCKα (0.0136 nM (Ki)) and MRCKβ (0.0233 nM (Ki))
- Shows antiproliferative effects with greatest activity in hematologic cancer cells
- Inhibits MLC phosphorylation and blocks SCC12 squamous cell carcinoma motility and invasion
- Topical application significantly decreases phosphorylated MRCKα S1003 staining and tumor volumes
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