Tetrahydrofuran
Medchemexpress LLC Nateglinide | 105816-04-4 | MFCD00875706 | 99.95% | 100 MG
Nateglinide is a D-phenylalanine derivative that acts as an orally active, short-acting insulinotropic agent and a DPP IV inhibitor. It functions by inhibiting ATP-sensitive K+ channels in pancreatic β-cells and is utilized in the treatment of type 2 (non-insulin-dependent) diabetes mellitus. This product is intended for research use only and is not sold to patients.
- Acts as an orally active, short-acting insulinotropic agent
- Functions as a DPP IV inhibitor
- Inhibits ATP-sensitive K+ channels in pancreatic β-cells
- Used for the treatment of type 2 diabetes mellitus
- Inhibits dinitrophenol-induced KATP currents
- Stimulates human C-peptide secretion
- Improves postprandial glucose concentrations
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran anhydrous
Tetrahydrofuran (THf) is a saturated cyclic ether mainly used as an organic solvent. On long term storage it forms organic peroxides. This process can be suppressed by adding butylated hydroxytoluene (BHT) as a stabilizer. BHT removes the free radicals required for the peroxide formation. It constitutes the key fragment of various natural products (polyether antibiotics). THf forms double hydrate with hydrogen sulfide crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies.
eMolecules 121138-01-0 | 3-Iodotetrahydrofuran | Ambeed | MFCD09878873 | 198.003 | C4H7IO | 98.000 | IC1CCOC1 | 100mg | 571783746
3-Iodotetrahydrofuran | Ambeed | 121138-01-0 | MFCD09878873 | 198.003 | C4H7IO | 98.000 | IC1CCOC1 | 100mg | 571783746
Medchemexpress LLC Tmx-4116 | 2766385-56-0 | 99.8% | C17H19N5O4S | 100 MG
TMX-4116 is a casein kinase 1α (CK1α) degrader. It exhibits a degradation preference for CK1α with DC50s less than 200 nM in MOLT4, Jurkat, and MM.1S cells.
- Can be utilized for research related to multiple myeloma.
- Demonstrates a high degradation preference for CK1α in MOLT4 cells at 1 μM for 4 hours.
- Induces primary target degradation of CK1α without downregulating PDE6D, IKZF1, and IKZF3 in MOLT4 cells.
Medchemexpress LLC Smyrindioloside | 87592-77-6 | 424.40 | 1 MG
Smyrindioloside is a natural product isolated from the bark of *Streblus indicus*. It is for research use only and not sold to patients.
- High purity: 99.32%
- White to off-white solid appearance
- Available in various quantities, including 1 mg, 5 mg, 10 mg, and 50 mg
- In-stock availability for 1 mg size
- Detailed documentation available, including data sheet, COA, and SDS
Medchemexpress LLC Melanin probe-2 | 1285446-04-9 | 99.4% | 300.19 | 100 MG
Melanin probe-2 (compound 5) is a non-radioactive bromopicolinamide precursor utilized in the synthesis of 18F-Labeled Picolinamide PET probes. This product is for research use only.
- Non-radioactive bromopicolinamide precursor
- Used for the synthesis of 18F-Labeled Picolinamide PET probe
- Research use only
Medchemexpress LLC AST5902 trimesylate | 2929417-90-1 | 98.75% | 842.88 | 100 MG
AST5902 trimesylate is the principal metabolite of Alflutinib in vitro and in vivo. It exhibits antineoplastic activity, and Alflutinib is known as an EGFR inhibitor.
- Principal metabolite of Alflutinib
- Exhibits antineoplastic activity
- Targets EGFR
Medchemexpress LLC p-Ethynylphenylalanine hydrochloride | 188640-63-3 | 99.23% | 225.67 | 50 MG
p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine hydrochloride) is a potent, selective, reversible, and competitive inhibitor of tryptophan hydroxylase (TPH), with a Ki of 32.6 μM. It is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Potent, selective, reversible, and competitive inhibitor of tryptophan hydroxylase (TPH).
- Click chemistry reagent.
- Contains an Alkyne group for CuAAc reactions.
- Selectively and reversibly inhibits the biosynthesis of serotonin.
- Decreases 5-HT and 5-HIAA levels in the rat midbrain (at 30 mg/kg; i.p.).
- Does not inhibit aromatic amino acid decarboxylase.
Medchemexpress LLC SR8278 | 1254944-66-5 | 99.94% | C18H19NO3S2 | 100 MG
SR8278 is a REV-ERBα antagonist that inhibits its transcriptional repression activity with an EC50 of 0.47 μM.
- Used to regulate metabolism in organisms
- Studies biological rhythm
- Researches Duchenne muscular dystrophy
- Researches Alzheimer's disease
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran | 109-99-9 | MFCD00005356 | 6x1l
Tetrahydrofuran | Purity: 99% | Mol Wt: 72.11 | 109-99-9 | MFCD00005356 | 6x1l
Sigma Aldrich Fine Chemicals Biosciences 2 Methyltetrahydrofuran Bi
We are committed to bringing you Greener Alternative Products which adhere to one or more of The 12 Principles of Greener Chemistry. This product is a biorenewable and thus aligns with Safer Solvents and Auxiliaries and Use of Renewable feedstocks. Click here for more information.2-Methyltetrahydrofuran (2-MTHf) a 2-methyl substituted tetrahdrofuran is a biomass derived solvent. It is a potential greener solvent alternative for organic synthesis. It shows resistance to reduction by lithium making it a promising candidate as electrolytes in lithium batteries. Its polarity and Lewis base strength is intermediate between tetrahydrofuran (THf) and diethyl ether. The ring opening reaction of 2-MTHf has been studied using acid chloride and iodide to form secondary chlorides and primary iodides respectively. On long term storage tetrahydrofuran forms organic peroxides. This process can be suppressed by adding butylated hydroxytoluene (BHT) as a stabilizer. BHT removes the free radicals re
Medchemexpress LLC Dalpiciclib 50mg | 1637781-04-4 | 50 MG
Dalpiciclib is an orally active, selective inhibitor of cyclin-dependent kinases CDK4 and CDK6 intended for preclinical research use. It is supplied as a powder and is characterized by CAS 1637781-04-4, molecular formula C25H30N6O2, and molecular weight 446.54 g/mol. For research use only; not for human or clinical use.
- Selective CDK4/6 inhibition with low-nanomolar potency
- High chemical purity suitable for analytical and biological studies
- Supplied as a powder for flexible formulation and dosing
- Stable under recommended storage conditions for long-term use
- Characterized by validated analytical data and CAS identification
![Medchemexpress LLC 2-[[4-(diethylamino)-2-hydroxyphenyl]methylene]hydrazide-4-pyridinecarboxylic acid | 140405-36-3 | 99.7% | 312.37 | C17H20N4O2 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000247220.png-250.jpg)
Medchemexpress LLC 2-[[4-(diethylamino)-2-hydroxyphenyl]methylene]hydrazide-4-pyridinecarboxylic acid | 140405-36-3 | 99.7% | 312.37 | C17H20N4O2 | 25 MG
RSVA405 is a potent, orally active activator of AMP-activated protein kinase (AMPK) used in preclinical research. It facilitates CaMKKβ-dependent AMPK activation, inhibits mTOR, promotes autophagy and lysosomal degradation of Aβ, and exhibits anti-inflammatory effects via STAT3 inhibition. Activity is observed in vitro (EC50 ≈ 1 μM) and in vivo in metabolic and renal models.
- Potent AMPK activator with an EC50 of approximately 1 μM.
- Promotes autophagy and lysosomal degradation of Aβ.
- Inhibits mTOR and modulates adipocyte differentiation.
- Exhibits anti-inflammatory effects through STAT3 inhibition.
- Demonstrated in vitro and in vivo activity in metabolic and renal models.
- Supplied as a light yellow to yellow solid with high purity.