PBX-7011 TFA is a derivative of camptothecin, which inhibits the expressions of cancer-related survival genes DDX5, Survivin, Mcl-1, and XIAP in FaDu cells. It degrades DDX5 proteins and exhibits anticancer activity. This product is for research use only and not sold to patients.
- Inhibits expression of cancer-related survival genes DDX5, Survivin, Mcl-1, and XIAP.
- Degrades DDX5 proteins.
- Exhibits anticancer activity.
- Targets Bcl-2 family and Survivin.
- Involves the apoptosis pathway.
- Is a derivative of camptothecin.