Organooxygen compounds
Medchemexpress LLC Snap 94847 hydrochloride | 1781934-47-1 | >98.0% | 515.03 g/mol | C29H32F2N2O2·HCl | 1 ML
SNAP 94847 hydrochloride is a potent, selective melanin-concentrating hormone receptor 1 (MCH1) antagonist supplied as a concentrated research solution. It is used to probe MCH1 signaling in neuroscience studies and has demonstrated effects on appetite-related behavior, anxiety, and hippocampal neurogenesis in preclinical models.
- Potent MCH1 antagonist with Ki = 2.2 nM and Kd = 530 pM.
- High selectivity over α1A and D2 receptors (>80-fold and >500-fold).
- Provided as a 10 mM solution in DMSO for laboratory use.
- Purity ≥98.0% by HPLC.
- Molecular weight 515.03 g/mol; formula C29H32F2N2O2·HCl.
- Store desiccated at room temperature; handle solvents per safety guidance.
Medchemexpress LLC Nordoxepin hydrochloride | 2887-91-4 | 99.9% | 301.81 | C18H20ClNO | 5 MG
Nordoxepin hydrochloride is the major metabolite of the tricyclic antidepressant doxepin, provided as a research-grade chemical standard for analytical and laboratory applications. This compound is intended for non-clinical research use only.
- Major metabolite of doxepin, useful as an analytical standard.
- Purity 99.9%.
- Molecular formula C18H20ClNO and molecular weight 301.81.
- White to off-white solid appearance.
- Available in small solid quantities suitable for analytical work.
- Store sealed at 4°C; solutions are stable at -80°C for long-term storage.
Medchemexpress LLC AMXI-5001 hydrochloride | 98.1% | C25H21ClFN5O3 | 1 ML
AMXI-5001 hydrochloride is a potent, orally active, and dual PARP1/2 and microtubule polymerization inhibitor. It shows selective antitumor cytotoxicity across a wide range of human cancer cells with significantly lower IC50s compared to existing clinical PARP1/2 inhibitors, and can induce complete regression of established tumors, including very large ones.
- Potent and orally active
- Dual PARP1/2 and microtubule polymerization inhibitor
- Selective antitumor cytotoxicity across a wide range of human cancer cells
- Significantly lower IC50s compared to existing clinical PARP1/2 inhibitors
- Induces complete regression of established tumors
Medchemexpress LLC Ladostigil hydrochloride | 209394-18-3 | 99.9% | 308.80 g·mol⁻¹ | C16H21ClN2O2 | 10 MG
Ladostigil hydrochloride is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase, exhibiting neuroprotective, antioxidant, and anti-inflammatory activities. It is used in research on depression and neurodegenerative disorders, and its hydrochloride salt includes an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition for click-chemistry applications.
- Dual inhibitor of cholinesterase and monoamine oxidase.
- Neuroprotective, antioxidant, and anti-inflammatory activities.
- Suitable for research on depression and neurodegeneration.
- Contains an alkyne group for click-chemistry conjugation.
- Provided with analytical documentation such as data sheet and COA.
Medchemexpress LLC Nebivolol hydrochloride | 152520-56-4 | MFCD07357273 | 99.9% | 50 MG
Nebivolol hydrochloride is an orally active beta receptor blocker with high beta(1)-receptor affinity. It possesses direct vasodilator properties and adrenergic blocking characteristics. This compound is used for the research of various diseases such as hypertension, coronary artery disease, congestive heart failure, and ischemic heart disease.
- Orally active beta receptor blocker
- High beta(1)-receptor affinity
- Direct vasodilator properties
- Adrenergic blocking characteristics
- Improves endothelial dysfunction
- Stimulates endothelial nitric oxide synthase activity
- Antioxidative properties
- Inhibits haCSMC and haEC proliferation
- Induces moderate apoptosis
- Increases NO formation and decreases endothelin-1 secretion
Medchemexpress LLC Flavoxate hydrochloride (Standard) | 3717-88-2 | 99.7% | 100 MG
Flavoxate hydrochloride (Standard) | 3717-88-2 | 99.7% | 100 MG
Medchemexpress LLC GB111-NH2 hydrochloride | 99.3% | 610.14 | 50 MG
GB111-NH2 hydrochloride is a cysteine cathepsin inhibitor, and can be used for cancer study. For research use only. We do not sell to patients.
- Cysteine cathepsin inhibitor.
- Can be used for cancer study.
- For research use only.
Medchemexpress LLC Aptiganel hydrochloride | 137160-11-3 | 99.8% | 339.86 g·mol⁻1 | C20H22ClN3 | 5 MG
Aptiganel hydrochloride is the hydrochloride salt of aptiganel, a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist with reported neuroprotective activity. It is provided as a purified research chemical for studies of excitotoxicity and NMDA receptor-mediated signaling.
- Non-competitive NMDA receptor antagonist
- Reported neuroprotective activity
- Hydrochloride salt form
- High purity (99.8%)
- Suitable for in vitro and in vivo research
- Molecular weight 339.86 g·mol⁻1
Medchemexpress LLC Lecozotan hydrochloride | 433282-68-9 | 98.7% | 520.02 g/mol | C28H30ClN5O3 | 10 MG
Lecozotan hydrochloride is the hydrochloride salt of lecozotan, a selective 5-HT1A receptor antagonist used in research to investigate serotonergic signaling and cognitive function. The compound is provided as a characterized solid for in vitro and in vivo studies, with supporting analytical documentation available.
- High reported purity of 98.7% suitable for research applications.
- Off-white to light-yellow solid, easy to handle and store.
- Molecular weight 520.02 g/mol and formula C28H30ClN5O3 for precise dosing calculations.
- Available in small milligram quantities for early-stage studies.
- COA, data sheet, and SDS available for quality and safety verification.
Medchemexpress LLC VTP-27999 Hydrochloride | 1264191-73-2 | 98.18% | C26H42Cl2N4O5 | 100 MG
VTP-27999 Hcl is an alkyl amine Renin inhibitor useful for Hypertension and End-Organ Diseases, targeting Renin with an IC50 value.
- Alkyl amine Renin inhibitor
- Useful for hypertension and end-organ diseases
- Targets renin (IC50 value)
Medchemexpress LLC Cl-amidine hydrochloride | 1373232-26-8 | MFCD22201084 | 99.8% | 347.24 g·mol⁻¹ | C14H20Cl2N4O2 | 1 MG
Cl-amidine hydrochloride is an orally active peptidylarginine deiminase (PAD) inhibitor used in biochemical and cellular research to probe histone citrullination, neutrophil extracellular trap formation, apoptosis, and related signaling pathways. Reported IC50 values are ~0.8 μM (PAD1), 6.2 μM (PAD3), and 5.9 μM (PAD4). Supplied as a high-purity solid; follow manufacturer storage recommendations.
- Potent inhibitor of PAD enzymes with reported low-micromolar activity.
- High purity suitable for biochemical assays and cell-based studies.
- Stable solid formulation; store under inert atmosphere at low temperature.
- Available in solution to facilitate cell treatment workflows.
- For research use only; not for human or veterinary applications.
Medchemexpress LLC Adrogolide hydrochloride | 166591-11-3 | 99.6% | 435.96 g·mol⁻¹ | C22H26ClNO4S | 10 MG
Adrogolide hydrochloride is a research prodrug that is converted rapidly in plasma to A-86929, a dopamine D1 receptor agonist used in preclinical neuropharmacology studies. It has been studied in Parkinson's disease models for effects on motor function and dyskinesia.
- Research prodrug to a dopamine D1 receptor agonist for pharmacology studies.
- Used in preclinical Parkinson's disease and dyskinesia models.
- High analytical purity (99.6%).
- Available in small-mass research pack sizes suitable for in vitro and in vivo studies.
- Soluble in DMSO; forms clear solutions at ≥ 2.5 mg/mL.
Medchemexpress LLC Tocainide hydrochloride | 71395-14-7 | MFCD00941502 | 99.5% | 228.72 g/mol | C11H17ClN2O | 10 MG
Tocainide hydrochloride is a sodium channel blocker provided as a high-purity hydrochloride salt for research use. It is supplied as a solid off-white to gray powder and is intended for biochemical and pharmacological studies involving sodium channel modulation.
- High purity suitable for research applications.
- Sodium channel blocker used in electrophysiology and pharmacology studies.
- Off-white to gray solid physical form.
- Recommended storage: 4°C for solid; in solvent, -80°C for 6 months or -20°C for 1 month under nitrogen.
- Molecular weight 228.72 g/mol and CAS number 71395-14-7 for identification.
Medchemexpress LLC Pumosetrag Hydrochloride | 194093-42-0 | 99.8% | 339.84 | 1 ML
Pumosetrag Hydrochloride (MKC-733; DDP-733) is an orally available 5-HT3 partial agonist developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.
- Orally available 5-HT3 partial agonist
- Developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease
- Activity profile varies by species and region of the intestine
- Inhibits responses to ondansetron, confirming action on 5-HT3 receptors
- Delays liquid gastric emptying, stimulates fasting antroduodenal migrating motor complex activity, and accelerates small intestinal transit