Phenylpropanoids and polyketides
Medchemexpress LLC Hydrocinnamic acid-d5 | 35845-62-6 | 99.7% | 155.21 g·mol⁻1 | C9H5D5O2 | 25mg
Hydrocinnamic acid-d5 is the deuterium labeled Hydrocinnamic acid[1] Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities[2]
Medchemexpress LLC Oxytetracycline dihydrate | 6153-64-6 | 99.4% | 1 G
Oxytetracycline dihydrate is an antibiotic belonging to the tetracycline class. It potently inhibits Gram-negative and Gram-positive bacteria. It acts as a protein synthesis inhibitor, preventing the binding of aminoacyl-tRNA to the m-ribosomal RNA complex. Additionally, it exhibits anti-HSV-1 activity.
- Antibiotic belonging to the tetracycline class
- Potent inhibitor of Gram-negative and Gram-positive bacteria
- Protein synthesis inhibitor
- Possesses anti-HSV-1 activity
AdipoGen Formononetin
Chemical. CAS 485-72-3. Formula C16H12O4. MW 268.26. Formononetin is an isoflavonoid phytoestrogenic compound found in soy-based foods and is the precursor of daidzein. It acts as an agonist of the aryl hydrocarbon receptor and a selective inhibitor of ADH gamma the gamma-isoform of alcohol dehydrogenase. It displays potent antitumor, antiviral, anti-inflammatory inhibits NLRP3 inflammasome, antioxidant, neuroprotective and neuroinflammatory properties. Also shown to have vasorelaxant, antihypertensive and antihyperglycemic AMPK activator properties. Induces cell cycle arrest and apoptosis in several cancer cells in vitro and in vivo and shows anti-angiogenic FGFR2 inhibitor, anti-invasive and anti-migratory effects. Increases adipocyte thermogenesis by modulating PPARgamma activity.
Medchemexpress LLC Oxytetracycline (dihydrate) | 6153-64-6 | 99.4% | 5 G
Oxytetracycline dihydrate is an antibiotic from the tetracycline class, known for its potent inhibition of Gram-negative and Gram-positive bacteria. It functions as a protein synthesis inhibitor by preventing the binding of aminoacyl-tRNA to the m-ribosomal RNA complex, and also demonstrates anti-HSV-1 activity.
- Antibiotic belonging to the tetracycline class
- Potently inhibits Gram-negative and Gram-positive bacteria
- Acts as a protein synthesis inhibitor
- Prevents binding of aminoacyl-tRNA to m-ribosomal RNA complex
- Exhibits anti-HSV-1 activity
Apexbio Technology LLC Doxorubicin (Adriamycin) HCl 25316-40-9 10mM (in 1mL DMSO)
Doxorubicin hydrochloride an anthracycline antibiotic derivative exhibits cytotoxic activity and is widely utilized as an anticancer chemotherapeutic agent Its mechanism involves intercalating into DNA double-strands inhibiting DNA topoisomerase II activity and consequently interrupting replication processes causing DNA damage and altered chromatin structure by histone displacement In biomedical research settings doxorubicin hydrochloride is employed in vitro and in animal models to study therapeutic strategies against hematologic malignancies solid tumors and sarcomas Reported IC50 values vary with cell type and assay conditions typically ranging between approximately 0 1 M to 2 M in various tumor-derived cell models
Medchemexpress LLC Potassium benzoate 100g
Potassium benzoate (Benzoic acid potassium) is a kind of biological materials or organic compounds that are widely used in life science research[1]
Apexbio Technology LLC Daidzein 486-66-8 10mM (in 1mL DMSO)
Daidzein is an isoflavone compound derived from soybeans structurally classified as a phytoestrogen with structural similarity to endogenous estrogen It has been widely investigated for its potential in biomedical research particularly in oncology and cell biology studies Daidzein exhibits anticancer-related biological activity possibly via modulation of hormonal signaling pathways and interference with cell cycle progression as exemplified by inducing cell cycle arrest at the G1 phase in cultured mammalian cells Additionally it demonstrates antioxidant properties providing protective effects against oxidative stress-mediated cell injury such as hepatic cellular damage induced by chemical carcinogens Daidzein is thus employed in studies focused on hormone-dependent tumorigenesis cell-cycle regulation mechanisms and oxidative-stress-induced cellular responses
Cayman Chemical 7-Acetoxy-4-methylcoumarIn 10g
A fluorogenic substrate for carboxylesterase and AChE; upon hydrolysis by carboxylic esterase or AChE, 4-MU is released, which displays pH-dependent excitation maxima of 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively, and an emission maximum between 445-454 nm; has been used to detect the presence of carboxylesterases in isolated human lung tissue
Medchemexpress LLC Z-Entacapone | 145195-63-7 | 305.29 | 25 MG
(Z)-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor Entacapone. It is also a potential impurity found in commercial preparations of Entacapone and a degradant of Entacapone formed by UV light exposure.
- Metabolite of the catechol-O-methyltransferase (COMT) inhibitor Entacapone
- Potential impurity in commercial Entacapone preparations
- Degradant of Entacapone formed by UV light exposure
- Molecular formula: C14H15N3O5
- SMILES: O=C(N(CC)CC)/C(C#N)=C\C1=CC([N+]([O-])=O)=C(O)C(O)=C1
- Targets COMT
- Involves metabolic enzyme/protease and neuronal signaling pathways
Cambridge Isotope Laboratories 4-HYDROXY-3-METHOXYCINNAMIC ACID (FERULIC ACID) (1',2',3'-13C3, 99%), 1 MG, 1261170-81-3
4-HYDROXY-3-METHOXYCINNAMIC ACID (FERULIC ACID) (1',2',3'-13C3, 99%), 1 MG, 1261170-81-3
Medchemexpress LLC Coumarin-C2-TCO | 2488174-16-7 | >98.0% | 455.55 | C25H33N3O5 | 10 MG
Coumarin-C2-TCO is a coumarin-derived fluorescent dye functionalized with a trans-cyclooctene (TCO) reactive handle that undergoes rapid inverse electron-demand Diels-Alder (iEDDA) reactions with tetrazine-bearing molecules for bioorthogonal labeling and conjugation.
- Fluorescent coumarin core provides a dye scaffold for imaging and detection.
- TCO reactive handle enables fast, bioorthogonal iEDDA conjugation to tetrazines.
- Suitable for labeling biomolecules and developing fluorescent probes in chemical biology workflows.
- Offered in small research quantities for synthesis and assay development.
Medchemexpress LLC Oxytetracycline dihydrate | 6153-64-6 | 99.4% | 500 MG
Oxytetracycline dihydrate is an antibiotic of the tetracycline class, acting as a potent inhibitor of both Gram-negative and Gram-positive bacteria. It functions by preventing the binding of aminoacyl-tRNA to the m-ribosomal RNA complex and also exhibits anti-HSV-1 activity. This compound is synthesized by a type II polyketide synthase from microorganisms, specifically *Streptomyces rimosus*.
- Inhibits Gram-negative and Gram-positive bacteria
- Acts as a protein synthesis inhibitor
- Exhibits anti-HSV-1 activity
- Light yellow to yellow solid appearance
Medchemexpress LLC Potassium benzoate 500g
Potassium benzoate (Benzoic acid potassium) is a kind of biological materials or organic compounds that are widely used in life science research[1]
Medchemexpress LLC 5Z-7-Oxozeaenol | 253863-19-3 | 99.3% | 10 MG
5Z-7-Oxozeaenol is a natural anti-protozoan compound of fungal origin, serving as a potent, irreversible, and selective inhibitor of TAK1 and VEGF-R2, with IC50 values of 8 nM and 52 nM, respectively.
- Potent, irreversible, and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 (TAK1, IC50: 8.1 nM).
- Less active on MEK1 (IC50: 411 nM).
- Prevents inflammation by inhibiting TAK1 MAPK kinase kinase catalytic activity.
- Inhibitor of VEGF-R2 (IC50: 52 nM).
- Also inhibits VEGF-R3 (IC50: 110 nM), FLT3 (IC50: 170 nM), PDGFR-β (IC50: 340 nM), B-RAF VE (IC50: 6300 nM), and SRC (IC50: 6600 nM).
- Inhibits JNK/p38 pathway (signal-specific, not a direct inhibitor).
- Suppresses PMA-induced AP-1 activity in KT cells; no effect on IL-1-induced NF-kB activity in KK cells.