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Filtered Search Results
Medchemexpress LLC Loperamide hydrochloride | 34552-83-5 | 99.8% | 1 ML
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Loperamide hydrochloride (R-18553 hydrochloride) is an opioid receptor agonist and a selective, competitive human intestinal carboxylesterases (hiCE) inhibitor. It is primarily recognized for its anti-diarrheal effects and is extensively used in research settings to study its impact on various biological pathways.
- Induces hallmarks of ER stress and autophagy in GBM cells and MEFs.
- Decreases LC3B and GABARAP lipidation levels in ATF4 KO cells compared to WT cells.
- Used in cell autophagy assays.
- Store at 4°C, sealed and away from moisture.
- For solutions, store at -80°C for up to 6 months or -20°C for 1 month, sealed and away from moisture.
- Shipped at room temperature for durations less than 2 weeks.
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Medchemexpress LLC Ivabradine (hydrochloride) | 148849-67-6 | 99.7% | 100 MG
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Ivabradine (hydrochloride) is a potent and orally active blocker of HCN (hyperpolarization-activated cyclic nucleotide-gated) channels. It inhibits the cardiac pacemaker current (If) and is known to reduce heart rate in a dose-dependent manner without affecting blood pressure. This compound exhibits anticonvulsant, anti-ischaemic, and anti-anginal activities, making it suitable for various research applications.
- Potent and orally active HCN channel blocker
- Inhibits cardiac pacemaker current (If)
- Reduces heart rate dose-dependently without affecting blood pressure
- Exhibits anticonvulsant activity
- Exhibits anti-ischaemic activity
- Exhibits anti-anginal activity
- Intended for research and analytical applications
- Purity of 99.7%
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Medchemexpress LLC Forodesine hydrochloride | 284490-13-7 | 98.4% | 302.71 | 25 MG
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Forodesine hydrochloride is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. It is a potent human lymphocyte proliferation inhibitor and can induce apoptosis in leukemic cells by increasing dGTP levels.
- Potent and orally active purine nucleoside phosphorylase (PNP) inhibitor.
- Inhibits human lymphocyte proliferation.
- Induces apoptosis in leukemic cells.
- Excellent oral bioavailability in mice.
- Effective in prolonging life span in mouse models.
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Medchemexpress LLC Forodesine hydrochloride | 284490-13-7 | 99.9% | 302.71 | 1 ML
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Forodesine hydrochloride is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor. It acts as a potent human lymphocyte proliferation inhibitor and can induce apoptosis in leukemic cells by increasing dGTP levels. It has excellent oral bioavailability in mice.
- Highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor
- Potent human lymphocyte proliferation inhibitor
- Induces apoptosis in leukemic cells
- Excellent oral bioavailability in mice
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Medchemexpress LLC Arecaidine hydrochloride | 6018-28-6 | 1 ML
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Arecaidine hydrochloride is a pyridine alkaloid. It functions as a potent GABA uptake inhibitor and acts as a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1), competitively inhibiting L-proline uptake.
- Pyridine alkaloid
- Potent GABA uptake inhibitor
- Functions as a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1)
- Competitively inhibits L-proline uptake
- Molecular formula: C7H12ClNO2
- Derived from plants, specifically Palmae Areca catechu L.
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eMolecules 6052-73-9 | 5,6-Dihydropyridin-2(1H)-one | Combi-Blocks | MFCD19216835 | 97.117 | C5H7NO | 97.000 | O=C1NCCC=C1 | 5g | 401043033
5,6-Dihydropyridin-2(1H)-one | Combi-Blocks | 6052-73-9 | MFCD19216835 | 97.117 | C5H7NO | 97.000 | O=C1NCCC=C1 | 5g | 401043033
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eMolecules 34696-73-6 | 3,5-Dimethylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD01311497 | 209.369 | C8H9BrMg | 0.000 | [Br-].Cc1cc(C)cc([Mg+])c1 | 500ml | 437237110
3,5-Dimethylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 34696-73-6 | MFCD01311497 | 209.369 | C8H9BrMg | 0.000 | [Br-].Cc1cc(C)cc([Mg+])c1 | 500ml | 437237110
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eMolecules 402-26-6 | (3-(trifluoromethyl)phenyl)magnesium bromide, 0.50 M in THF | Synthonix249.313 | C7H4BrF3Mg | 0.000 | [Br-].FC(F)(F)c1cccc([Mg+])c1 | 100ml | 702445992
(3-(trifluoromethyl)phenyl)magnesium bromide, 0.50 M in THF | Synthonix | 402-26-6249.313 | C7H4BrF3Mg | 0.000 | [Br-].FC(F)(F)c1cccc([Mg+])c1 | 100ml | 702445992
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eMolecules 2386-58-5 | Ethenesulfonamide | ChemScene | MFCD00051751 | 107.130 | C2H5NO2S | 97.000 | NS(=O)(=O)C=C | 1g | 572289931
Ethenesulfonamide | ChemScene | 2386-58-5 | MFCD00051751 | 107.130 | C2H5NO2S | 97.000 | NS(=O)(=O)C=C | 1g | 572289931
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Medchemexpress LLC Ilginatinib hydrochloride | 1239358-85-0 | 98.9% | 425.89 | 1 G
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Ilginatinib hydrochloride | 1239358-85-0 | 98.9% | 425.89 | 1 G
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Medchemexpress LLC 3-buten-2-one, 4-(2-naphthalenyl)-, (3E)- | 51557-10-9 | 99.9% | 196.24 | 1 G
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(E)-4-(Naphthalen-2-yl)but-3-en-2-one is a small active molecule that serves as a versatile building block. This compound demonstrates significant anti-leukemic activity, effectively inhibiting the proliferation of K562 human chronic myeloid leukemia cells.
- Small active molecule
- Can be used as a building block
- Exhibits anti-leukemic activity
- Inhibits proliferation of K562 cells with an IC50 of 7.6 μM
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Medchemexpress LLC Moroxydine (hydrochloride) | 3160-91-6 | 99.4% | 10 G
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Moroxydine hydrochloride (ABOB hydrochloride) is a broad-spectrum agent with multi-antiviral activities against both DNA and RNA viruses. These include influenza virus, herpes simplex, varicella zoster, measles, mumps disease, and hepatitis C virus. It demonstrates excellent antiviral activity with low cytotoxicity to cells infected by dsRNA viruses like grass carp reovirus (GCRV) and large DNA viruses such as giant salamander iridovirus (GSIV).
- Blocks GCRV-induced cytopathic effects
- Removes nucleocapsids in ctenopharyngodon idella kidney (CIK) cells
- Maintains normal morphological structure of CIK cells
- Significantly inhibits apoptosis
- Inhibits caspase 3 activity and Bax expression
- Down-regulates Bcl-2 levels
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Medchemexpress LLC Vardenafil hydrochloride | 224785-91-5 | 99.8% | 1 ML
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Vardenafil hydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. It competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis, leading to increased cGMP levels and can be used for research related to erectile dysfunction, hepatitis, and diabetes.
- Selective and orally active PDE5 inhibitor
- Increases intracellular cGMP levels
- Suitable for research on erectile dysfunction, hepatitis, and diabetes
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eMolecules 312693-16-6 | 3-Methoxybenzylzinc chloride, 0.50 M in THF | Synthonix | MFCD01319883 | 221.990 | C8H9ClOZn | 0.000 | [Cl-].COc1cccc(C[Zn+])c1 | 100ml | 702445957
3-Methoxybenzylzinc chloride, 0.50 M in THF | Synthonix | 312693-16-6 | MFCD01319883 | 221.990 | C8H9ClOZn | 0.000 | [Cl-].COc1cccc(C[Zn+])c1 | 100ml | 702445957
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eMolecules 693-03-8 | Butylmagnesium bromide, 1.0 M in THF | Synthonix | MFCD00672091 | 161.325 | C4H9BrMg | 0.000 | [Br-].CCCC[Mg+] | 50ml | 702445845
Butylmagnesium bromide, 1.0 M in THF | Synthonix | 693-03-8 | MFCD00672091 | 161.325 | C4H9BrMg | 0.000 | [Br-].CCCC[Mg+] | 50ml | 702445845
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