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ML162-yne is a GPX4-inhibitor affinity probe designed for click-chemistry applications. The molecule contains an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) for labeling or capturing target-engaged proteins. It is supplied as a high-purity solid or as a DMSO solution and is intended for research use only.
Enables selective labeling via copper-catalyzed azide-alkyne cycloaddition.
Functions as an affinity probe for glutathione peroxidase 4 (GPX4).
Supplied with high purity for reliable experimental results.
Available as solid and ready-to-use DMSO solution formats.
Stable under recommended storage conditions for long-term use.
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8-Bromooct-1-yne is an organobromide reagent containing a terminal alkyne and a bromide leaving group. It is used as a synthetic building block in organic chemistry and for bioconjugation workflows such as copper-catalyzed azide-alkyne cycloaddition (click chemistry). Store under nitrogen at 4°C; in solution, keep at -80°C (up to 6 months) or -20°C (up to 1 month). CAS: 81216-13-9; formula: C8H13Br; MW: 189.09.
Terminal alkyne for conjugation and cross-coupling reactions.
Bromide leaving group enables nucleophilic substitution.
Suitable for copper-catalyzed click chemistry with azide partners.
Supplied in small-scale quantities for research applications.
Store under inert atmosphere to preserve stability.
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8-Bromooct-1-yne is a brominated terminal alkyne reagent used in organic synthesis and copper-catalyzed click chemistry. It offers both a reactive alkyne for azide coupling and a bromide leaving group for substitution, supplied in small research-scale quantities and requiring inert storage.
Terminal alkyne reagent for organic synthesis and click chemistry.
Contains a bromide leaving group for nucleophilic substitution.
Molecular formula C8H13Br; molecular weight 189.09 g/mol.
Suitable for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
Available in small research-scale pack sizes for laboratory use.
Store under nitrogen at 4°C; in solvent: -80°C (6 months) or -20°C (1 month).
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
8-Bromooct-1-yne is a brominated terminal alkyne reagent used as a synthetic building block in organic synthesis and chemical biology research. It combines a terminal alkyne for click-type reactions with a bromide leaving group for nucleophilic substitution, enabling installation of alkynyl linkers and chain elaboration in probe and linker synthesis.
8-Bromooct-1-yne is a terminal alkyne bearing a bromide substituent used as a synthetic building block for organic synthesis and chemical biology. It participates in alkyne-based coupling and substitution reactions, enabling installation of functional groups or linkers in small-molecule synthesis and bioconjugation.
Terminal alkyne with a reactive bromide group.
Compatible with copper-catalyzed azide-alkyne cycloaddition (click chemistry) and cross-coupling reactions.
Useful as an alkylating building block for functionalization and chain extension.
Provided as a 250 mg research reagent; store under inert atmosphere at low temperature for stability.
Molecular formula C8H13Br; molecular weight 189.09 g/mol.
Purity not specified on the manufacturer product page.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More