Biotin and derivatives
Medchemexpress LLC Methoxy polyethylene glycol N-hydroxysuccinimide ester | 92451-01-9 | 98.0% | 10MG
Methoxy polyethylene glycol N-hydroxysuccinimide ester, average molecular weight 20,000 Da, is an NHS-activated methoxy-PEG reagent that reacts efficiently with primary amines to form stable amide bonds. It is supplied as a solid for research use and is commonly used for PEGylation of peptides and proteins, linker construction in targeted degraders, and general bioconjugation to improve solubility and pharmacokinetic properties.
- Reacts with primary amines to form stable amide linkages.
- Improves solubility and reduces immunogenicity of conjugates.
- Provides a 20 kDa hydrophilic spacer for linker design.
- Supplied as a high-purity reagent suitable for research applications.
- Compatible with standard coupling and purification workflows.
Medchemexpress LLC M-PEG-NHS ester | 92451-01-9 | 98.0% | (C2H4O)nC7H9NO5 | 50 MG
M-PEG-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based protac linker
- Used in the synthesis of protacs
- Protacs contain two different ligands connected by a linker
- Features a ligand for an E3 ubiquitin ligase and another for the target protein
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC M-PEG-NHS ester (MW 20000) | 92451-01-9 | 98.0% | (C2H4O)nC7H9NO5 | 25 MG
M-PEG-NHS ester (MW 20000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs are compounds that consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. This mechanism allows PROTACs to utilize the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Peg-based protac linker
- Used in the synthesis of protacs
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC m-PEG-NHS ester (MW 5000) | 92451-01-9 | 95.0% | (C2H4O)nC7H9NO5 | 50 MG
m-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This solid, white to off-white compound boasts a purity of 95.0% and is intended strictly for research purposes.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- For research use only
- Solid appearance
- White to off-white color
- 95.0% purity
Medchemexpress LLC m-PEG-NHS ester | 92451-01-9 | MFCD06412227 | 98.0% | 2,000 Da | C9H13NO6 | 500 MG
m-PEG-NHS ester is a methoxy-terminated polyethylene glycol reagent functionalized with an N-hydroxysuccinimide (NHS) ester for selective conjugation to primary amines. With an average molecular weight of approximately 2,000 Da, it is used to introduce PEG chains that improve solubility, stability, and circulation time of proteins, peptides, and small molecules. Supplied as a 500 mg solid.
- Methoxy-terminated PEG with NHS ester reactive group.
- Average molecular weight ~2,000 Da for spacer and solubility enhancement.
- High purity suitable for bioconjugation (reported 98.0%).
- Reacts selectively with primary amines to form stable amide linkages.
- Commonly used for PEGylation, linker construction, and bioconjugation.
Medchemexpress LLC m-PEG-NHS ester | 92451-01-9 | MFCD06412227 | 90.0% | 350 g/mol | (C2H4O)nC7H9NO5 | 10 MG
m-PEG-NHS ester (MW 350) is a methoxy-terminated polyethylene glycol activated as an N-hydroxysuccinimide (NHS) ester for covalent PEGylation of primary amine-containing molecules. It is intended to improve solubility and stability, reduce immunogenicity, and enable bioconjugation and surface functionalization in research applications.
- Activated NHS ester for efficient coupling to primary amines.
- Methoxy termination prevents crosslinking and limits multi-attachment.
- Improves solubility and stability of biomolecules.
- Reduces immunogenicity and can extend circulation half-life.
- Suitable for protein, peptide, and small-molecule PEGylation.
- Available in small mg-scale quantities for research use.
Medchemexpress LLC M-PEG-NHS ester | 92451-01-9 | MFCD01867746 | 98.0% | 2000 (average) | (C2H4O)nC7H9NO5 | 100 MG
m-PEG-NHS ester (MW 2000) is an NHS-activated methoxy poly(ethylene glycol) reagent for PEGylation of biomolecules. It reacts with primary amines to modify proteins, peptides, and small molecules to improve solubility, stability, and pharmacokinetics. Supplied as a white to off-white solid for research use, it is offered in multiple pack sizes and stored sealed away from moisture.
Medchemexpress LLC m-PEG-NHS ester | 92451-01-9 | 98.0% | Poly(oxy-1,2-ethanediyl), α-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-ω-methoxy- | 250 MG
m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a specific protein, thereby leveraging the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Targets PROTAC linkers
- Exploits the intracellular ubiquitin-proteasome system
- Facilitates selective degradation of target proteins
Medchemexpress LLC M-PEG-NHS ester | 92451-01-9 | 98.0% | Poly(oxy-1,2-ethanediyl), α-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-ω-methoxy- | 100 MG
M-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are designed to selectively degrade target proteins by exploiting the intracellular ubiquitin-proteasome system.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC m-PEG-NHS ester (MW 10000) | 92451-01-9 | 98.0% | Poly(oxy-1,2-ethanediyl), α-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-ω-methoxy- | 500 MG
m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs. These PROTACs leverage the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. This product is intended for research purposes only.
- PEG-based PROTAC linker
- Enables the synthesis of PROTACs
- Utilizes the ubiquitin-proteasome system
- Achieves selective degradation of target proteins
- Suitable for research use only
Medchemexpress LLC M-PEG-NHS ester (MW 10000) | 92451-01-9 | 98.0% | Poly(oxy-1,2-ethanediyl), α-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-ω-methoxy- | 25 MG
m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker. It is for research use only and not sold to patients. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. These compounds contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Composed of PEG, alkyl, and ether groups
Medchemexpress LLC m-PEG-NHS ester (MW 10000) | 92451-01-9 | 98.0% | Poly(oxy-1,2-ethanediyl), α-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-ω-methoxy- | 1 G
m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These molecules feature two distinct ligands joined by a linker: one targeting an E3 ubiquitin ligase and the other binding to a specific target protein. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system to degrade target proteins
- Solid, white to off-white appearance
- For research use only
Medchemexpress LLC M-PEG-NHS ester (MW 10000) | 92451-01-9 | 98.0% | Poly(oxy-1,2-ethanediyl), α-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-ω-methoxy- | 50 MG
M-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs