Furans
eMolecules 1353858-99-7 | Medchem Express | CX-6258 (hydrochloride hydrate) | 5mg | 415688005 | HY-18095A | MFCD26142938 | 516.42 | C26H27Cl2N3O4
Ambeed | 4-Chloro-7-fluoroquinazoline | 1g | 525099592 | A182189 | 16499-62-0 | MFCD08236729 | 182.580 | C8H4ClFN2
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Medchemexpress LLC HY-U00213 5mg Medchemexpress, Furaprofen CAS:67700-30-5 Purity:>98%
Medchemexpress, HY-U00213 5mg Furaprofen CAS:67700-30-5 Furaprofen (R803) is an effective HCV replication inhibitor. Furaprofen (R803) is substantially more potent against genotype 1a and 1b replicons (EC50, ~30 nM) than against the genotype 2a replicon (EC50, ~1,000 nM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Azimilide dihydrochloride | 149888-94-8 | MFCD00918091 | >97.0% | 530.88 g/mol | C23H30Cl3N5O3 | 10 MG
Azimilide dihydrochloride is the dihydrochloride salt of azimilide, a class III antiarrhythmic research compound that blocks cardiac potassium currents. It is used in vitro to study cardiac electrophysiology, ion channel pharmacology, and mechanisms of arrhythmia in cellular and tissue models.
- Dual IKs and IKr (hERG) blocker useful for cardiac electrophysiology studies.
- Characterized IC50 values enable comparative ion channel pharmacology.
- Offered as solid and as a ready-to-use 10 mM solution for assay flexibility.
- Stable dihydrochloride salt with defined molecular weight and formula for reproducible dosing.
- Suitable for in vitro investigations of atrial and ventricular fibrillation mechanisms.
Medchemexpress LLC CX-6258 (hydrochloride) | 1353859-00-3 | 99.0% | 498.40 | 50 MG
CX-6258 hydrochloride is a potent and kinase-selective pan-Pim kinases inhibitor. It effectively inhibits Pim-1, Pim-2, and Pim-3, causing dose-dependent inhibition of pro-survival proteins like Bad and 4E-BP1. In vitro studies show it diminishes ectopic NKX3.1 levels, while in vivo, it exhibits robust efficacy in Pim kinases driven tumor models, demonstrating significant tumor growth inhibition.
- Potent and kinase-selective pan-Pim kinases inhibitor.
- Inhibits phosphorylation of pro-survival proteins.
- Diminishes steady-state levels of ectopic NKX3.1 in PC3 cells.
- Exhibits robust efficacy in Pim kinases driven tumor models in vivo.
- For research use only.
Medchemexpress LLC HY-100578 5mg Medchemexpress, AGK2 CAS:304896-28-4 Purity:>98%
Medchemexpress, HY-100578 5mg AGK2 CAS:304896-28-4 AGK2 is a selective SIRT2 inhibitor with IC 50 of 3.5 μM. AGK2 can also inhibit SIRT1 and SIRT3 with IC 50 of 30 and 91 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Dantrolene (sodium hemiheptahydrate) | 24868-20-0 | MFCD07357270 | 99.8% | 399.31 g/mol | C14H16N4NaO8.5 | 10MM 1ML
Dantrolene sodium hemiheptahydrate is the sodium salt hydrate form of dantrolene used as a research reagent. It acts as a direct-acting skeletal muscle relaxant and inhibitor of calcium release from the sarcoplasmic reticulum, commonly used in studies of calcium homeostasis, malignant hyperthermia models, and muscle spasm pharmacology.
- Purity 99.8% for reliable experimental consistency.
- Molecular weight 399.31 g/mol and formula C14H16N4NaO8.5.
- CAS number 24868-20-0 for substance traceability.
- Solid, yellow to orange physical appearance.
- Available in multiple pack sizes to suit laboratory needs.
- Suitable for in vitro and in vivo research into calcium-related mechanisms.
Medchemexpress LLC Dantrolene | 7261-97-4 | MFCD00867709 | 98.4% | 314.26 g/mol | C14H10N4O5 | 10MG
Dantrolene is a research-grade skeletal muscle relaxant and ryanodine receptor (RyR) inhibitor used to study calcium homeostasis, malignant hyperthermia, muscle spasm, and related neurological or ischemic conditions. It acts as a non-competitive glutathione reductase inhibitor (reported Ki 111.6 μM; IC50 52.3 μM) and inhibits Ca2+ release from RyR1 and RyR3, making it useful for biochemical and cell-based studies.
- Direct RyR1 and RyR3 calcium-release inhibitor.
- Used in research on malignant hyperthermia and muscle spasm.
- Non-competitive glutathione reductase inhibitor with reported Ki/IC50 values.
- Available in solid and solution formats suitable for assays.
- High reported purity (~98.4%).
- Molecular formula C14H10N4O5; molecular weight ~314.26 g/mol.
Medchemexpress LLC Dantrolene sodium hemiheptahydrate | 24868-20-0 | MFCD07357270 | 99.8% | 399.31 g·mol⁻¹ | C14H9N4NaO5 · 3.5H2O | 500MG
Dantrolene sodium hemiheptahydrate is the sodium salt hydrate form of dantrolene, a direct-acting skeletal muscle relaxant and ryanodine receptor (RyR) inhibitor used as a research reagent in studies of muscle spasm, malignant hyperthermia, and calcium-related pathophysiology. Supplied in multiple pack sizes for laboratory use.
- High purity (99.8%).
- Inhibits RyR-mediated Ca2+ release for calcium signaling studies.
- Supplied as the hemiheptahydrate crystalline form.
- Molecular weight 399.31 g·mol⁻¹.
- Available in multiple pack sizes, including 500 mg.
- Intended for laboratory research use only.
Medchemexpress LLC 4E1RCat | 328998-25-0 | 99.0% | C28H18N2O6 | 100 MG
4E1RCat is an inhibitor of cap-dependent translation, inhibiting the eIF4E:eIF4GI interaction with an IC50 of approximately 4 μM. It interferes with eIF4G and 4E-BP binding, blocking capped mRNA translation activated by CDK1/CYCB1. This compound is for research use only and affects chemosensitivity and targets translation in mice models.
- Inhibits cap-dependent translation
- Interferes with eIF4E:eIF4GI interaction
- Blocks capped mRNA translation
- Affects chemosensitivity in specific tumor types in mice
- Sensitizes lymphomas to doxorubicin
- Targets translation in mice
Medchemexpress LLC Azimilide | 149908-53-2 | 99.0% | 457.95 | 5 MG
Azimilide is a class III antiarrhythmic agent that blocks potassium channels in the heart. It is a dual blocker of IKs and IKr potassium channels. It also blocks HERG channels, and inhibits L-type calcium current (ICa) and sodium current (INa). It can be used for the study of atrial fibrillation and ventricular fibrillation.
- Class III antiarrhythmic agent
- Dual blocker of IKs and IKr potassium channels
- Blocks HERG channels
- Inhibits L-type calcium current (ICa)
- Inhibits sodium current (INa)
- Can be used for the study of atrial fibrillation and ventricular fibrillation
- Significantly reduces the occurrence of ventricular tachycardia (VT) induced by electrical stimulation (PES) in dogs
- Prolongs the effective refractory period of the ventricle and the QTc interval
- Provides significant protection against ischemia-induced ventricular fibrillation and improves survival rates
Medchemexpress LLC CX-6258 (hydrochloride) | 1353859-00-3 | 99.0% | 498.40 | 5 MG
CX-6258 hydrochloride is a potent and kinase-selective pan-Pim kinases inhibitor, with IC50s of 5 nM, 25 nM, and 16 nM for Pim-1, Pim-2, and Pim-3, respectively.
- Purity of 99.03%.
- Solid appearance.
- Orange to red color.
- Soluble in DMSO (10 mg/mL, requires ultrasonic).
- Soluble in H2O (1 mg/mL, requires ultrasonic, warming, and heating to 60°C).
- In vivo solubility of ≥ 2.5 mg/mL in a specific solution.
eMolecules 1353859-00-3 | Medchem Express | CX-6258 (hydrochloride) | 5mg | 601586574 | HY-18095B | MFCD28137787 | 498.4 | C26H25Cl2N3O3
Ambeed | 4-Chloro-6-(trifluoromethyl)quinazoline | 250mg | 552737394 | A494799 | 16499-64-2 | MFCD09837194 | 232.590 | C9H4ClF3N2
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Selleck Chemical LLC 4E1RCat-5mg
4E1RCat is a dual inhibitor of eIF4E:eIF4G and eIF4E:4E-BP1 interaction, and inhibits the binding of eIF4G to eIF4E.
=O | 5g | 495866317](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502168152.JPG-250.jpg)
eMolecules 141645-23-0 | (2-Butyl-5-nitrobenzofuran-3-yl)(4-(3-(dibutylamino)propoxy)phenyl)methanone | Synthonix - Stock | MFCD18072491 | 508.659 | C30H40N2O5 | 95.000 | CCCCN(CCCC)CCCOc1ccc(cc1)C(=O)c1c(CCCC)oc2ccc(cc12)[N+]([O-])=O | 5g | 495866317
(2-Butyl-5-nitrobenzofuran-3-yl)(4-(3-(dibutylamino)propoxy)phenyl)methanone | Synthonix - Stock | 141645-23-0 | MFCD18072491 | 508.659 | C30H40N2O5 | 95.000 | CCCCN(CCCC)CCCOc1ccc(cc1)C(=O)c1c(CCCC)oc2ccc(cc12)[N+]([O-])=O | 5g | 495866317