Furans
Apexbio Technology LLC Azimilide 149908-53-2 50mg
Azimilide (CAS 149908-53-2) is a small molecule under investigation for potential anti-arrhythmic activity classified pharmacologically as a class III anti-arrhythmic agent Its mechanism involves inhibition of cardiac delayed rectifier potassium channels specifically targeting both rapid (IKr) and slow (IKs) components By modulating these currents azimilide prolongs cardiac repolarization influencing cardiac rhythm Although not approved for therapeutic use azimilide is currently undergoing clinical evaluation in the United States and serves as a tool compound in arrhythmia-related biomedical research
Apexbio Technology LLC Azimilide 149908-53-2 5mg
Azimilide (CAS 149908-53-2) is a small molecule under investigation for potential anti-arrhythmic activity classified pharmacologically as a class III anti-arrhythmic agent Its mechanism involves inhibition of cardiac delayed rectifier potassium channels specifically targeting both rapid (IKr) and slow (IKs) components By modulating these currents azimilide prolongs cardiac repolarization influencing cardiac rhythm Although not approved for therapeutic use azimilide is currently undergoing clinical evaluation in the United States and serves as a tool compound in arrhythmia-related biomedical research
Medchemexpress LLC Azimilide | 149908-53-2 | 99.0% | 457.95 | 5 MG
Azimilide is a class III antiarrhythmic agent that blocks potassium channels in the heart. It is a dual blocker of IKs and IKr potassium channels. It also blocks HERG channels, and inhibits L-type calcium current (ICa) and sodium current (INa). It can be used for the study of atrial fibrillation and ventricular fibrillation.
- Class III antiarrhythmic agent
- Dual blocker of IKs and IKr potassium channels
- Blocks HERG channels
- Inhibits L-type calcium current (ICa)
- Inhibits sodium current (INa)
- Can be used for the study of atrial fibrillation and ventricular fibrillation
- Significantly reduces the occurrence of ventricular tachycardia (VT) induced by electrical stimulation (PES) in dogs
- Prolongs the effective refractory period of the ventricle and the QTc interval
- Provides significant protection against ischemia-induced ventricular fibrillation and improves survival rates
Medchemexpress LLC Modoflaner | 1331922-53-2 | Not found | 98.3% | C23H10F12IN3O2 | 10MG
Modoflaner is an isophenylamide insecticide research compound that may act through allosteric regulation of gamma-aminobutyric acid (GABA)-gated chloride channels. It is supplied as a white to off-white solid with reported high purity and is intended for research use only.
- Isophenylamide insecticide acting via allosteric modulation of GABA-gated chloride channels.
- Supplied as a white to off-white solid suitable for analytical and biological research.
- High reported purity (≈98.3%) supports assay and screening applications.
- Recommended storage conditions available for solid and solution to preserve stability.
- Available in small research pack sizes for laboratory use.
Medchemexpress LLC Tovinontrine (IMR-687) | 2062661-53-2 | 99.8% | 394.47 | 1 ML
Tovinontrine (IMR-687) | 2062661-53-2 | 99.8% | 394.47 | 1 ML
Medchemexpress LLC BV02 | 292870-53-2 | MFCD00356631 | 99.8% | 377.36 | C20H15N3O5 | 50 MG
BV02 is a small-molecule research compound that inhibits 14-3-3 protein-protein interactions and has reported antibacterial activity. It modulates cell signaling by enhancing PARP and caspase-3 cleavage, and by inducing apoptosis and autophagy, making it useful for cellular and infection-related studies.
- Inhibits 14-3-3 protein-protein interactions.
- Induces apoptosis and autophagy in cell-based assays.
- Enhances PARP and caspase-3 cleavage.
- Shows reported antibacterial activity.
- Supplied at high purity suitable for research use.
- Available in solid and ready-to-use solution formats.
Medchemexpress LLC Azimilide | 149908-53-2 | MFCD00867099 | 99.0% | 457.95 | C23H28ClN5O3 | 10 MG
Azimilide is a class III antiarrhythmic agent used in research to block cardiac delayed rectifier potassium channels (IKs and IKr). It is commonly used in electrophysiology and arrhythmia studies to probe ion channel function and pharmacological effects.
- Class III potassium channel blocker targeting IKs and IKr.
- Also inhibits L-type calcium and sodium currents at higher concentrations.
- Suitable for in vitro electrophysiology and arrhythmia models.
- High purity grade for research use.
- Free base and dihydrochloride salt forms available; follow SDS storage guidance.
Medchemexpress LLC Bv02 | 292870-53-2 | MFCD00356631 | 99.8% | 377.36 g/mol | C20H15N3O5 | 10 MG
BV02 is a small-molecule inhibitor of 14-3-3 protein-protein interactions used in preclinical research to study apoptosis, autophagy, Akt signaling, and host-pathogen responses. It is provided for in vitro experiments in solid form and as a DMSO solution.
- High chemical purity (≈99.8%).
- Well-defined molecular formula C20H15N3O5 and molecular weight 377.36 g/mol.
- Indexed by CAS number 292870-53-2 for unambiguous identification.
- Available in multiple solid sizes and as a 10 mM solution in DMSO for assay readiness.
- Reported to modulate PARP and caspase-3 cleavage and to affect Akt signaling in cell studies.
- Supplied for research use only; not for human or veterinary use.
Medchemexpress LLC BV02 | 292870-53-2 | MFCD00356631 | 99.8% | 377.36 g/mol | C20H15N3O5 | 5 MG
BV02 is a small-molecule 14-3-3 protein-protein interaction inhibitor provided as a white to off-white solid for research use. It has been reported to induce apoptosis and autophagy and to display antibacterial activity in preclinical studies. The product is supplied with stability guidelines for powder and solution storage.
Medchemexpress LLC 2-isopropylphenyl (2-(naphthalen-2-yl)ethyl)carbamate | 1354359-53-7 | MFCD20926355 | 99.5% | 333.42 | C22H23NO2 | 5 MG
JW480 is a potent, selective small-molecule inhibitor of the serine hydrolase KIAA1363, supplied as a high-purity research reagent for biochemical and cellular studies. It is provided as a solid or as a 10 mM solution in DMSO for in vitro applications.
- Potent and selective inhibitor of KIAA1363.
- High purity (about 99.5%).
- Available as solid in multiple sizes and as a 10 mM DMSO solution.
- Molecular formula C22H23NO2; molecular weight 333.42 g/mol.
- Soluble in DMSO and suitable for biochemical and cellular assays.
- For research use only; not for human or diagnostic use.
Medchemexpress LLC 2-isopropylphenyl (2-(naphthalen-2-yl)ethyl)carbamate | 1354359-53-7 | MFCD20926355 | 99.5% | 333.42 g/mol | C22H23NO2 | 50 MG
JW480 is a potent, selective small-molecule inhibitor of the serine hydrolase KIAA1363 (AADACL1) used in biochemical and cell-based research to probe enzyme function and related pathways. This compound is supplied for research use only.
- Potent, selective inhibitor of KIAA1363.
- Intended for research use only.
- High purity: 99.54%.
- Chemical formula: C22H23NO2.
- Molecular weight: 333.42 g/mol.
- CAS number: 1354359-53-7.
- Supplied as a 50 mg quantity.
Medchemexpress LLC 2-isopropylphenyl N-(2-naphthalen-2-yl)ethyl carbamate | 1354359-53-7 | MFCD20926355 | 99.5% | 333.42 g/mol | C22H23NO2 | 10 MG
JW480 is a potent, selective carbamate inhibitor of the serine hydrolase KIAA1363 (AADACL1). It is used as a research reagent to probe KIAA1363 function in lipid metabolism and cancer-relevant cellular pathways, and is supplied with characterization data appropriate for biochemical and cellular studies.
- Selective inhibitor of the serine hydrolase KIAA1363.
- Suitable for biochemical and cell-based assays.
- Carbamate-based small-molecule structure for target engagement studies.
- High purity and defined molecular properties for reproducible results.
- Provided with catalog and registry identifiers for traceability.
![Medchemexpress LLC 2-[(2-carboxyphenyl)amino]-4-chlorobenzoic acid | 63329-53-3 | MFCD00866065 | 99.4% | 291.68 g/mol | C14H10ClNO4 | 50MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000237302.png-250.jpg)
Medchemexpress LLC 2-[(2-carboxyphenyl)amino]-4-chlorobenzoic acid | 63329-53-3 | MFCD00866065 | 99.4% | 291.68 g/mol | C14H10ClNO4 | 50MG
Lobenzarit is a small-molecule immunomodulator used in preclinical research that has reported anti-oxidative and anti-inflammatory properties. It is supplied as a high-purity research reagent (CAS 63329-53-3) and is used in vitro and in vivo to study immune modulation and anti-arthritic effects.
- High purity suitable for research use.
- Reported immunomodulatory and anti-oxidative activity.
- Available in multiple small-scale sizes for preclinical studies.
- Stable when stored under recommended conditions (powder and in solvent).
- Molecular formula C14H10ClNO4; molecular weight 291.68 g/mol.
Medchemexpress LLC 3-Pyridinecarboxamide, 6-fluoro-N-[2-fluoro-3-[[[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluorometh | 1331922-53-2 | 98.3% | 715.23 | 50 MG
Modoflaner is an isophenylamide insecticide intended for research use only. It may act through allosteric regulation of gamma-aminobutyric acid-gated chloride channels.
- Isophenylamide insecticide
- May act through allosteric regulation of gamma-aminobutyric acid-gated chloride channels
- Effectively kills moth, xylophone, and gray planthopper
- Prevents female adult ticks from laying eggs or eggs from hatching
- White to off-white solid appearance
- Purity of 98.26%
- Store at 4°C, protected from light; in solvent at -80°C for 6 months or -20°C for 1 month, protected from light
![Medchemexpress LLC 2-(dimethylamino)-5-[(2-methyl-1-oxopropyl)amino]-N-[(1R)-1-phenylethyl]-benzamide | 1393441-53-6 | 98.6% | 50MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000232147.png-250.jpg)
Medchemexpress LLC 2-(dimethylamino)-5-[(2-methyl-1-oxopropyl)amino]-N-[(1R)-1-phenylethyl]-benzamide | 1393441-53-6 | 98.6% | 50MG
2-(dimethylamino)-5-[(2-methyl-1-oxopropyl)amino]-N-[(1R)-1-phenylethyl]-benzamide | 1393441-53-6 | 98.6% | 50MG
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