Lactams
Medchemexpress LLC Sulbactam pivoxil | 69388-79-0 | MFCD00867003 | 98.0% | 347.38 | C14H21NO7S | 100 MG
Sulbactam pivoxil is the pivoxil ester prodrug of sulbactam, a β-lactamase inhibitor supplied as a research/analytical standard. The material is provided as a white to off-white solid with reported purity of 98.0% and a molecular weight of 347.38, and is used to support studies of oral bioavailability, pharmacokinetics, and β-lactamase inhibition.
- Prodrug form improves oral absorption compared with sulbactam.
- Useful as a reference standard for pharmacokinetic and microbiology studies.
- High reported purity supports analytical and formulation work.
- Available in solid and ready-to-use solution formats for flexibility.
- Recommended storage conditions provided to preserve stability.
Medchemexpress LLC Sulbactam | 68373-14-8 | 100.0% | 100 MG
Sulbactam is a competitive, irreversible beta-lactamase inhibitor. It exhibits antimicrobial activity against multidrug-resistant (MDR) Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex and possesses a broad spectrum of antibacterial activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. It is suitable for use as a laboratory chemical and in the manufacture of substances.
- Competitive, irreversible beta-lactamase inhibitor
- Antimicrobial activity against multidrug-resistant (MDR) Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex
- Broad spectrum antibacterial activity
- Solid form, light yellow to yellow in color
- Suitable for laboratory chemical applications
- Melting point: 154-157°C
- Boiling point: 356°C at 760 mmHg
- Flash point: 297.1°C
- For research use only
eMolecules 68373-14-8 | Medchem Express | Sulbactam | 100mg | 446272524 | HY-B0334 | 233.24 | C8H11NO5S
Medchem Express | Sulbactam | 100mg | 446272524 | HY-B0334 | 68373-14-8 | 233.240 | C8H11NO5S
U.S. Pharmacopeia Sulbactam, 68373-14-8, MFCD00867005, 250mg
Molecular formula C8H11NO5S, Molecular weight 233.24, Melting Point 298.4 - 303.8 °F (148 - 151 °C) (also reported as 170 °C), Synonyms: Penicillanic acid 1,1-dioxide. Cold Shipment Required
Apexbio Technology LLC Tazobactam (sodium salt) 89785-84-2 250mg
Tazobactam sodium salt (CAS 89785-84-2) is a small-molecule inhibitor targeting -lactamases It is designed to irreversibly bind to -lactamases thereby preventing the enzyme-mediated hydrolysis of -lactam antibiotics Tazobactam sodium salt exerts its biological activity primarily through -lactamase inhibition In microbiological assays tazobactam demonstrates intrinsic antibacterial activity against several Acinetobacter strains typically with MIC values of 8 mg/L (range 2 32 mg/L) Based on these pharmacological properties tazobactam sodium salt holds research potential in microbiological assessments and efficacy evaluations of -lactam antibiotic combinations
Medchemexpress LLC Thalidomide-O-C6-NHBoc | 2509093-23-4 | 95.99% | C24H31N3O7 | 50 MG
Thalidomide-O-C6-NHBoc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. It is for research use only and not sold to patients. The product appears as an off-white to light yellow solid with a molecular weight of 473.52.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates Thalidomide based cereblon ligand
- Linker used in PROTAC technology
- For research use only
- Appears as an off-white to light yellow solid
- Molecular weight of 473.52
Medchemexpress LLC Thalidomide-5-PEG6-NH2 hydrochloride | 574.02 g/mol | C25H36ClN3O10 | 10 MG
Thalidomide-5-PEG6-NH2 hydrochloride is a thalidomide-derived cereblon ligand designed as a synthetic building block for targeted protein degradation research. The molecule includes a PEG6 linker terminating in a primary amine (hydrochloride salt) that enables conjugation to linkers or target ligands for PROTAC construction. Storage and handling conditions are provided to maintain stability.
Medchemexpress LLC Thalidomide-NH-PEG2-COOH | 2412056-45-0 | MFCD34368531 | 99.0% | C20H23N3O8 | 10MG
Thalidomide-NH-PEG2-COOH is a thalidomide-derived cereblon (CRBN) ligand-linker conjugate designed as a building block for PROTAC and targeted protein degradation research. It couples a CRBN-recruiting thalidomide moiety to a short PEG2 spacer terminated with a carboxylic acid, facilitating conjugation to warheads or scaffolds for degrader design.
- Thalidomide-based cereblon ligand for CRBN recruitment.
- PEG2 linker terminated with carboxylic acid for conjugation.
- Suitable as a building block for PROTAC synthesis and linker optimization.
- High purity (99.0%) supporting reproducible conjugation chemistry.
- Molecular formula C20H23N3O8; molecular weight 433.41 g/mol.
- Supplied in small milligram pack sizes for research use.
Medchemexpress LLC Thalidomide-4-O-CH2-COO(t-Bu) | 1950635-36-5 | MFCD32643096 | 99.3% | 388.37 | C19H20N2O7 | 10 MG
Thalidomide-4-O-CH2-COO(t-Bu) is a tert-butyl protected thalidomide derivative used as a cereblon (CRBN) binding ligand and as a synthetic intermediate in the preparation of PROTAC molecules. It is supplied for research use only and is not intended for human use.
- Tert-butyl protected thalidomide derivative suitable for deprotection under acidic conditions.
- Functions as a cereblon (CRBN) binding ligand for use in PROTAC design.
- High reported purity (~99.3%) for reliable research applications.
- Available in small research pack sizes (mg scale) for synthetic workflows.
- Stable at room temperature for extended storage; follow solvent storage recommendations for longer-term stability.
Medchemexpress LLC Thalidomide-PEG5-NH2 hydrochloride | 2703775-06-6 | MFCD34550803 | 95.2% | 529.97 g·mol⁻¹ | C23H32ClN3O9 | 5 MG
Thalidomide-PEG5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that combines a thalidomide-derived cereblon (CRBN) binding moiety with a PEG5 amine linker, supplied as the hydrochloride salt. It is intended for use in PROTAC design and chemical biology research involving CRBN-mediated protein degradation.
- Cereblon-binding thalidomide-derived ligand.
- PEG5 amine linker provides a flexible spacer for conjugation.
- Hydrochloride salt improves solubility and handling.
- Characterized by CAS 2703775-06-6 and molecular weight 529.97 g·mol⁻¹.
- Purity approximately 95.2% by LCMS.
- Intended for research use in targeted protein degradation studies.
Medchemexpress LLC Thalidomide O-amido C3-COOH | 2308035-51-8 | 98.4% | 417.37 g/mol | C19H19N3O8 | 50 MG
Thalidomide O-amido C3-COOH is a synthesized E3 ligase ligand-linker conjugate that combines a thalidomide-derived cereblon-binding moiety with a short linker terminating in a carboxylic acid. It is provided as a research-grade chemical for use in PROTAC design and related chemical biology applications.
- Contains thalidomide-based cereblon ligand
- Three-carbon (C3) linker with terminal carboxylic acid
- Molecular formula C19H19N3O8; molecular weight 417.37 g/mol
- Purity 98.4% (research grade)
- Supplied as a white solid suitable for chemical synthesis
- Intended for research use only, not for human or clinical use
Medchemexpress LLC Thalidomide-NH-PEG2-COOH | 2412056-45-0 | 99.0% | 433.41 | 25 MG
Thalidomide-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate. It incorporates the Thalidomide based cereblon ligand and a linker that is utilized in PROTAC technology. This product is intended for research use only.
- Synthesized E3 ligase ligand-linker conjugate
- Utilizes PROTAC technology
- Incorporates Thalidomide based cereblon ligand
- Intended for research use only
eMolecules D-acid-PEG4-Thalidomide-5-(PEG4-acid) | Broadpharm |770.782 | C35H50N2O17 | 98.000 | OC(=O)CCOCCOCCOCCOCCOc1cccc2C(=O)N(C3CCC(=O)N(CCOCCOCCOCCOCCC(O)=O)C3=O)C(=O)c12 | 100mg | 779524498
D-acid-PEG4-Thalidomide-5-(PEG4-acid) | Broadpharm |770.782 | C35H50N2O17 | 98.000 | OC(=O)CCOCCOCCOCCOCCOc1cccc2C(=O)N(C3CCC(=O)N(CCOCCOCCOCCOCCC(O)=O)C3=O)C(=O)c12 | 100mg | 779524498
Medchemexpress LLC Thalidomide-NH-PEG3-COOH | 2375283-62-6 | 98.9% | 477.46 | C22H27N3O9 | 5 MG
Thalidomide-NH-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that combines a thalidomide-derived cereblon ligand with a three-unit polyethylene glycol (PEG3) linker terminating in a carboxylic acid. It is intended as a modular building block for PROTAC development to recruit CRBN and enable linker attachment to target-binding ligands.
- Designed for PROTAC assembly and CRBN recruitment.
- Contains a PEG3 linker terminating in a carboxylic acid for facile conjugation.
- Incorporates a thalidomide-based cereblon ligand.
- High chemical purity (≈98.9%).
- Suitable for medicinal chemistry and chemical biology applications.
Medchemexpress LLC Thalidomide-Piperazine-Piperidine hydrochloride | 2599846-44-1 | 98.41% | 461.94 | 25 MG
Thalidomide-Piperazine-Piperidine hydrochloride is a synthesized E3 ligase ligand-linker conjugate. It incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. This product is for research use only.
- Incorporates thalidomide based cereblon ligand
- Utilizes a linker used in PROTAC technology
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins