Pyridines and derivatives
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Filtered Search Results
Selleck Chemical LLC Amcinonide
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Amcinonide (Cyclocort CL-34699) is an inhibitor of nitric oxide (NO) release from activated microglia with IC50 of 3 38 nM
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Selleck Chemical LLC Trifluoperazine
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Trifluoperazine (NSC-17474 RP-7623 SKF-5019) is an FDA-approved antipsychotic drug for schizophrenia It is an inhibitor of calmodulin (CaM) and Dopamine D2 receptor with an IC50 value of 1 2 nM for D2 receptor
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC TARC/CCL17 protein, dog (HEK293, His) | >95.0% | 10UG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Recombinant TARC/CCL17 protein derived from dog, expressed in HEK293 cells and C-terminally His-tagged. The product corresponds to residues A24-S99 (accession Q95N01), is supplied lyophilized, and is formulated in PBS with 6% trehalose; predicted molecular mass ~9.4 kDa. Provided with supporting documents and recommended storage for research use only.
- Expression host HEK293 for mammalian expression
- C-terminal His tag for purification and detection
- Residues A24-S99 sequence confirmed
- Lyophilized formulation in PBS with 6% trehalose
- Purity >95.0% by reducing SDS-PAGE
- Supplied with COA, SDS, and data sheet for quality control
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 5,6-trans-Travoprost | 1563176-59-9 | >95% | 1 MG
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5,6-trans-Travoprost is an isomer of Travoprost and can be utilized as an experimental control. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high-affinity, selective FP prostaglandin full receptor agonist. It demonstrates ocular hypotensive efficacy and holds potential for treating glaucoma and ocular hypertension.
- Isomer of Travoprost
- Can be used as an experimental control
- High-affinity, selective FP prostaglandin full receptor agonist
- Demonstrates ocular hypotensive efficacy
- Potential for treating glaucoma and ocular hypertension
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Medchemexpress LLC Cefprozil monohydrate | 121123-17-9 | 99.8% | 5 MG
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Cefprozil monohydrate is a second-generation cephalosporin antibiotic that exhibits broad-spectrum antibacterial activity and is orally active. It can be used for the study of pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections.
- Molecular weight of 407.44
- Chemical formula C18H21N3O6S
- Appears as a white to off-white solid
- Inhibits various bacteria including S. pyogenes and E. coli
- Exhibits antibacterial activity in mouse models
- Orally active
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eMolecules 93071-75-1 | 3-(Trifluoromethoxy)benzylamine | Key Organics/BIONET | MFCD00061267 | 191.153 | C8H8F3NO | 90.000 | NCc1cccc(OC(F)(F)F)c1 | 10mg | 564346144
3-(Trifluoromethoxy)benzylamine | Key Organics/BIONET | 93071-75-1 | MFCD00061267 | 191.153 | C8H8F3NO | 90.000 | NCc1cccc(OC(F)(F)F)c1 | 10mg | 564346144
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Medchemexpress LLC Tinidazole (Standard) | 19387-91-8 | 99.95% | 50 MG
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Tinidazole (Standard) is the analytical standard of Tinidazole, an orally available antibacterial agent and a 5-nitroimidazole with selective activity against anaerobic bacteria and protozoa. It is intended for research and analytical applications, commonly used in qualitative, quantitative, and methodological research experiments.
- Analytical standard of Tinidazole
- Orally available antibacterial agent
- Selective activity against anaerobic bacteria and protozoa
- Suitable for qualitative, quantitative, and methodological research experiments including HPLC, GC, and MS
- Purity of 99.95%
- Off-white solid appearance
- Molecular formula: C8H13N3O4S
- Molecular weight: 247.27
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Medchemexpress LLC Pregnenolone (3β-Hydroxy-5-pregnen-20-one) | 145-13-1 | 99.9% | 1 ML
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Pregnenolone is a potent neurosteroid and the primary precursor to various steroid hormones, including steroid ketones. It functions as a signaling-specific inhibitor of the cannabinoid CB1 receptor, thereby inhibiting the effects of tetrahydrocannabinol (THC) that are mediated by CB1 receptors. Pregnenolone has the ability to protect the brain from cannabis intoxication. Additionally, it acts as a TRPM3 channel activator and can weakly activate TRPM1 channels.
- Powerful neurosteroid
- Main precursor of various steroid hormones
- Signaling-specific inhibitor of cannabinoid CB1 receptor
- Inhibits THC effects mediated by CB1 receptors
- Can protect the brain from cannabis intoxication
- TRPM3 channel activator
- Weakly activates TRPM1 channels
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Medchemexpress LLC Nefiracetam | 77191-36-7 | 99.9% | 1 G
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Nefiracetam is a cognition-enhancing agent that activates nAChR, N-methyl-D-aspartate receptor (NMDAR), mGluR5, PKC, gamma-aminobutyric acid (GABA), and N/L-type Ca2+ channels. It promotes neuroplasticity and enhances neuroprotection. This compound is used in research related to Alzheimer's disease, epilepsy, and cerebral ischemia.
- Activates nAChR, NMDAR, mGluR5, PKC, GABA, and N/L-type Ca2+ channels
- Promotes neuroplasticity and neuroprotection
- Supports research in Alzheimer's disease, epilepsy, and cerebral ischemia
- Increases hippocampal neurotransmission
- Improves NMDA receptor-dependent long-term potentiation
- Enhances CaMKIIα and PKCα autophosphorylation
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Medchemexpress LLC Ersodetug 1mg | 1mg
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Ersodetug is an anti-INSR (insulin receptor) human IgG2 monoclonal antibody[1] Recommend Isotype Controls Human IgG2 kappa Isotype Control (HY-P99002)
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Medchemexpress LLC Pirlindole | 60762-57-4 | MFCD00447212 | 98.9% | 226.32 g/mol | C15H18N2 | 1 MG
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Pirlindole is a selective, reversible monoamine oxidase A (MAO-A) inhibitor with reported antiviral activity against enterovirus D68 and coxsackievirus B3. Supplied as a high-purity research chemical, it is intended for biochemical and virology studies and analytical applications.
- Selective, reversible MAO-A inhibition.
- Reported antiviral activity against enterovirus D68 and coxsackievirus B3.
- High chemical purity suitable for research use.
- Intended for biochemical and virology assays.
- Recommended sealed storage at -20°C; in solvent: -80°C (6 months), -20°C (1 month).
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Medchemexpress LLC DpC 10mM 1mL | 1382469-39-7 | 1 ML
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DpC (di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone) is an anti-tumor small molecule provided as a ready-to-use 10 mM solution in DMSO or as a solid for custom preparation. It inhibits cancer cell proliferation (reported IC50 0.007-0.096 μM) and is used in in vitro and in vivo studies.
- Ready-to-use 10 mM solution in DMSO, 1 mL.
- Also available as solid for custom stock preparation.
- High purity (~98.7%) suitable for biological assays.
- High solubility in DMSO (≈62.5 mg/mL) for convenient stock preparation.
- Storage: powder -20°C; prepared solutions -80°C for long-term stability.
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Medchemexpress LLC IL-23R protein, cynomolgus | 100UG
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Recombinant interleukin-23 receptor (IL-23R) extracellular domain from cynomolgus monkey, expressed in HEK293 cells and supplied as a C-terminal His-tagged, lyophilized protein for research applications. Provided in a 100 μg size, the protein shows an apparent molecular weight of 60-80 kDa on SDS-PAGE and has endotoxin <1 EU/μg. Formulated in PBS (pH 7.4) with trehalose and intended for research use only.
- Recombinant extracellular domain expressed in HEK293 cells.
- C-terminal His tag for detection and purification.
- Observed molecular weight 60-80 kDa by SDS-PAGE.
- Endotoxin level <1 EU/μg.
- Lyophilized formulation from PBS, typically with ~8% trehalose.
- Store at -20°C; after reconstitution stable at 4°C for 1 week.
- Recommended to aliquot and store at -20°C or -80°C for long term.
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BIOHIPPO mTfrc-sh1-GFP-BSD
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mTfrc-sh1-GFP-BSD shRNA lentiviral vector expressing GFP with Blasticidin selection for studies in Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated mouse Tfrc shRNA lentivirus High-titer shRNA lentiviral particles specific for mouse transferrin receptor (Tfrc CD71) The shRNA has been validated to meet or exceed 70% Tfrc knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells
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BIOHIPPO AAV-EF1a-rtTA-WPRE-hGH-polyA
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Recombinant adeno associated virus expressing rtTA under the EF1a promoter with WPRE and hGH polyA elements. The Tet responsive configuration enables doxycycline controlled expression, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
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