Pyridines and derivatives
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Filtered Search Results
Medchemexpress LLC RCN3 Mouse HEK293 50ug | 50ug
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RCN3 Protein a probable molecular chaperone ensures pulmonary surfactant homeostasis by aiding in proper biosynthesis and transport of SP-A SP-D and ABCA3 It exhibits anti-fibrotic activity by negatively regulating type I and type III collagen secretion RCN3 transiently associates with immature PCSK6 suggesting its role in PCSK6 maturation and secretion RCN3 Protein Mouse (HEK293 His) is the recombinant mouse-derived RCN3 protein expressed by HEK293 with C-His labeled tag
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Recombinant human CD131 protein (HEK293, His) | >95.0% | 500 UG
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Recombinant human CD131 extracellular domain (W17-W443) with a C-terminal His tag, expressed in HEK293 cells and supplied in sterile PBS for research applications such as binding assays and antibody characterization.
- Extracellular domain covering W17-W443.
- C-terminal His tag for purification and detection.
- Greater than 95.0% purity by reducing SDS-PAGE.
- Supplied in 0.22 μm filtered PBS, pH 7.4.
- Stable at -80°C for long-term storage; avoid repeated freeze-thaw cycles.
- Available in multiple research sizes, including 500 μg.
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Medchemexpress LLC Kras4B protein, human (G12S, His) | >95.0% | 100UG
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Recombinant human KRAS4B (G12S) with an N-terminal 6xHis tag, expressed in Escherichia coli and supplied as a lyophilized powder. The protein retains GDP/GTP binding and intrinsic GTPase activity and is intended for research applications investigating KRAS signaling and mutant-specific interactions. Supplied with high purity and recommended frozen storage to preserve activity.
- Contains G12S oncogenic mutation relevant for signaling studies.
- Includes N-terminal 6xHis tag for purification and detection.
- Expressed in Escherichia coli and provided as lyophilized powder.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Stable when stored at -20°C; aliquot to avoid freeze-thaw cycles.
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Medchemexpress LLC Colfosceril miristate (DMPC) | 18194-24-6 | 100.0% | 677.93 | 1 ML
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Colfosceril miristate (DMPC) is a synthetic phospholipid that exhibits antiproliferative effects on various tumors and is utilized in studies of lipid monolayers, bilayers, and drug delivery. It can stabilize Carmofur at neutral pH, shows cytotoxicity on several tumor cell lines (SHSY-5Y, MDA-MB-435s, and HT-1080), and enhances the ability of nanoparticles to enter PC-12 cells. In vivo, it promotes the diffusion of SPIONs from the substantia nigra to nearby brain regions in SD rats.
- Synthetic phospholipid
- Exhibits antiproliferative effects on tumors
- Used in studies of lipid monolayers, bilayers, and drug delivery
- Stabilizes Carmofur at neutral pH
- Shows cytotoxicity on various tumor cell lines
- Enhances nanoparticle entry into cells
- Promotes diffusion of SPIONs in brain regions
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Medchemexpress LLC NKp30/NCR3 Rat HEK 50ug | 50ug
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NKp30/NCR3 protein is a cell membrane receptor on natural killer (NK) cells that activates cytotoxicity by binding to ligands such as BAG6 and NCR3LG1 stimulating NK cells to respond against neighboring cells (including tumor cells) expressing these ligands NKp30/NCR3 Protein Rat (HEK293 His) is the recombinant rat-derived NKp30/NCR3 protein expressed by HEK293 with C-His labeled tag
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Apexbio Technology LLC Dorsomorphin (Compound C) 866405-64-3 50mg
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Dorsomorphin (Compound C CAS 866405-64-3) is a cell-permeable reversible ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) exhibiting a Ki value of 109 nM It displays high specificity towards AMPK relative to related kinases such as protein kinase A protein kinase C and Janus kinase 3 Additionally dorsomorphin acts as an inhibitor of BMP signaling by reducing phosphorylation of Smad1/5/8 leading to inhibited osteogenic differentiation elevated iron levels via decreased hepcidin transcription and enhanced human ESC self-renewal and neural induction
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BIOHIPPO AAV-EF1a-DIO-3XFlag-WPRE-hGH-polyA
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Recombinant adeno associated virus expressing 3XFlag under the EF1a promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
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Medchemexpress LLC BVT.13 | 756813-87-3 | 98.4% | 404.2 | C18H11Cl2N3O4 | 5 MG
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BVT.13 is an orally active, selective peroxisome proliferator-activated receptor gamma (PPARγ) agonist used as a research compound. It displays a maximal efficacy similar to rosiglitazone and has demonstrated antidiabetic activity in ob/ob mice, making it useful for studies of PPARγ signaling, metabolic regulation, and preclinical efficacy testing.
- Selective PPARγ agonist activity.
- Oral bioactivity demonstrated in animal models.
- Demonstrated antidiabetic efficacy in ob/ob mice.
- High purity: 98.4% (HPLC).
- Suitable for in vitro and in vivo research applications.
- Molecular weight 404.2; formula C18H11Cl2N3O4.
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Apexbio Technology LLC Apelin-13 217082-58-1 25mg
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Apelin-13 (CAS 217082-58-1) is an endogenous peptide ligand targeting the APJ receptor a G-protein-coupled receptor (GPCR) implicated in cardiovascular regulation fluid balance and as a co-receptor for HIV entry Apelin-13 activates APJ receptors with high potency exhibiting an EC50 around 0 37 nM In animal studies microinjection into brainstem regions modulates respiratory drive and blood pressure Clinically apelin-13 infusions can induce vasodilation elevate cardiac index and decrease systemic vascular resistance highlighting its utility in cardiovascular and neurophysiological research
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Medchemexpress LLC Integrin Linked ILK Antibody (YA3111) | 10 UL
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Integrin Linked ILK Antibody (YA3111) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Integrin Linked ILK.
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Conjugation: Non-conjugated
- SwissProt ID: Q13418
- Research field: Signal transduction
- Storage & stability: Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles
- Appearance: Liquid
- Shipping: Shipping with blue ice
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Medchemexpress LLC Pravastatin sodium | 81131-70-6 | 99.4% | 5 MG
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Pravastatin sodium is an HMG-CoA reductase inhibitor that acts against sterol synthesis. It belongs to the statin drug class and is used to lower cholesterol and prevent cardiovascular disease in conjunction with diet, exercise, and weight-loss.
- HMG-CoA reductase inhibitor
- IC50 of 5.6 μM against sterol synthesis
- Lowers cholesterol
- Prevents cardiovascular disease
- Inhibits cellular steroidgenesis in HepG2 cells with an IC50 of 1.37 μM
- Inhibits cholesterol synthesis in rat hepatocytes with an IC50 of 0.1 μM
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Medchemexpress LLC Libvatrep | 871814-52-7 | MFCD18711490 | 99.5% | 305.33 | C18H15N3O2 | 5 MG
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Libvatrep is a research-grade TRPV1 (vanilloid receptor) antagonist supplied as a solid for in vitro and in vivo pharmacology studies. The compound is provided with analytical documentation and recommended solvent/formulation protocols for experimental use, and is identified by CAS 871814-52-7.
- Potent TRPV1 antagonist for pharmacological research.
- High purity (~99.5%) suitable for analytical assays.
- Molecular weight 305.33 and formula C18H15N3O2.
- Available as small solid quantities and as DMSO solution formats.
- Formulation guidance provided for in vitro and in vivo use.
- Certificate of analysis and safety data sheet available.
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Medchemexpress LLC EFNB2A zebrafish H 10ug | 10ug
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The EFNB2A protein is a cell surface ligand of the Eph receptor that critically regulates migration repulsion and adhesion in neuronal vascular and epithelial development EFNB2A Protein zebrafish (HEK293 His) is the recombinant EFNB2A protein expressed by HEK293 with C-His labeled tag
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eMolecules 1203499-21-1 | 2-Chloro-6-iodo-5-methylpyridin-3-ol | Combi-Blocks | MFCD13563047 | 269.470 | C6H5ClINO | 98.000 | Cc1cc(O)c(Cl)nc1I | 1g | 401043634
2-Chloro-6-iodo-5-methylpyridin-3-ol | Combi-Blocks | 1203499-21-1 | MFCD13563047 | 269.470 | C6H5ClINO | 98.000 | Cc1cc(O)c(Cl)nc1I | 1g | 401043634
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Medchemexpress LLC 12-ketochenodeoxycholic acid | 2458-08-4 | MFCD00134876 | 99.8% | 406.56 g/mol | C24H38O5 | 1 ML
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12-ketochenodeoxycholic acid is a bile acid derivative and metabolic precursor of cholodeoxycholic acid supplied for research use. It is available as a white to off-white solid or as a ready-to-use 10 mM solution in DMSO, and is commonly used in studies of bile acid metabolism and gut microbiota metabolites.
- Purity 99.8%.
- CAS number 2458-08-4.
- Chemical formula C24H38O5; molecular weight 406.56 g/mol.
- Available as solid and as 10 mM solution in DMSO (1 mL).
- Appearance white to off-white solid.
- Storage: powder -20 °C (3 years) or 4 °C (2 years); in solvent -80 °C (6 months) or -20 °C (1 month).
- Solubility DMSO 100 mg/mL; ultrasonic assistance may be required.
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