Pyridines and derivatives
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- (1)
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- (8)
- (7)
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- (60)
- (867)
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- (19)
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- (2)
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- (1)
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- (5)
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- (1)
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- (2)
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- (54)
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- (1)
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- (2)
- (1)
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- (6)
- (7)
- (12)
- (1)
- (1)
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- (1)
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- (11)
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- (2)
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- (15)
- (1)
- (1)
- (1)
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- (1)
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Filtered Search Results
Aobchem AOBCHEM
5000926595 2 4-DIIODOBENZONITRILE 500MG
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Medchemexpress LLC Cardiolipin (heart, bovine) sodium | 383907-10-6 | MFCD11974098 | 99.0% | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Cardiolipin (heart, bovine) sodium is a research-grade mitochondrial phospholipid extracted from bovine heart tissue. Supplied as a white to off-white solid sodium salt with high purity, it is used as a reagent in biochemical assays, mitochondrial and lipid research, and for coating microplates in immunoassays. Store sealed, away from moisture and light; follow solvent-specific storage recommendations.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aobchem AOBCHEM
5000926690 6- PROPYLTHIO -3-PYRIDINECARBO
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Aobchem AOBCHEM
5000926757 -CYCLOPENTYL-4- 1 1-DIMETHYLE
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Medchemexpress LLC Niaprazine | 27367-90-4 | MFCD00867991 | 99.6% | 356.44 g/mol | C20H25FN4O | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Niaprazine (Standard) is an analytical reference material of niaprazine intended for research and analytical applications. It acts as a histamine H1-receptor antagonist with antihistamine and antiserotonin activities and is commonly used in pharmacological and sleep disorder studies. The product is supplied as a 100 mg solid with documented purity and supporting analytical documentation.
- Analytical reference standard for research and method validation.
- High purity: 99.6%.
- Molecular formula C20H25FN4O; molecular weight 356.44 g/mol.
- Suitable for pharmacological and sleep disorder research.
- Includes supporting documentation such as SDS and COA.
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Medchemexpress LLC BCL6-IN-5 | 2253878-09-8 | 99.8% | 396.27 | 25 MG
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BCL6-IN-5 is a potent BCL6 inhibitor. It was extracted from patent WO2018215801A1, example 1n, and exhibits a pIC50 of 5.82. This product is intended for research use only.
- Potent BCL6 inhibitor
- Derived from patent WO2018215801A1
- Exhibits a pIC50 of 5.82
- Suitable for research applications
- High purity (99.82%)
- Available as a solid, light yellow to yellow in color
- Soluble in DMSO for in vitro studies
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Apexbio Technology LLC HSP990 (NVP-HSP990) 934343-74-5 10mM (in 1mL DMSO)
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HSP990 (NVP-HSP990 CAS 934343-74-5) is a small molecule inhibitor targeting heat shock protein 90 (HSP90) specifically binding the N-terminal ATP-binding domain of Hsp90 Hsp90 and Grp94 with IC50 values of 0 6 0 8 and 8 5 nM respectively HSP990 inhibits TRAP1 ATPase activity (IC50 320 nM) and destabilizes the Hsp90-p23 complex in GTL-16 cells in a concentration- and time-dependent manner The compound reduces c-Met levels induces Hsp70 (EC50 37 nM and 20 nM respectively) and inhibits phosphorylation of ERK and AKT (EC50 11 and 6 nM) leading to suppression of cell proliferation in multiple tumor cell lines (GI50 4 40 nM) In vivo HSP990 has demonstrated antitumor activity in murine gastric cancer models
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Medchemexpress LLC Pepinh-MYD | 1421052-89-2 | 96.87% | 3388.03 | 1 MG
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Pepinh-MYD is a MyD88 inhibitor that includes a domain sequence from MyD88 TIR and a protein transduction sequence, which allows it to penetrate the cell membrane. It disrupts MyD88-mediated TLR signaling pathways, thereby inhibiting associated immune responses. This compound has potential for studying the role of MyD88 in viral infections.
- Penetrates cell membrane
- Inhibits MyD88-mediated TLR signaling pathways
- Potential for studying viral infections
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Medchemexpress LLC CDK/HDAC-IN-3 | 2944087-54-9 | 99.60% | 509.34 | 50 MG
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CDK/HDAC-IN-3 is an orally active HDACs/CDKs dual inhibitor. It potently and selectively inhibits CDK9, CDK12, CDK13, HDAC1, HDAC2, and HDAC3. This compound can be used for acute myeloid leukemia (AML), significantly inducing differentiation of leukemic stem-like cells and inhibiting AML proliferation. It also demonstrates inhibitory effects on U937, HL-60, SKNO-1, and Kaumi-1 cells.
- Potent and selective dual inhibition of HDACs/CDKs.
- Inhibits CDK9, CDK12, CDK13, HDAC1, HDAC2, HDAC3.
- Induces differentiation of leukemic stem-like cells.
- Inhibits AML proliferation.
- Effective against U937, HL-60, SKNO-1, and Kaumi-1 cells.
- Demonstrates adequate oral bioavailability.
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Medchemexpress LLC Ro4987655 | 874101-00-5 | 99.0% | 565.28 | 25 MG
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Ro4987655 is an orally active and highly selective MEK inhibitor with an IC50 of 5.2 nM for inhibition of MEK1/MEK2. It potently inhibits the mitogen-activated protein kinase signaling pathway activation and tumor cell growth, and inhibits proliferation of NCI-H2122 cells in a dose-dependent manner. This compound appears as a solid, white to off-white in color.
- Highly selective MEK1/MEK2 inhibitor
- Potently inhibits MAPK signaling pathway and tumor cell growth
- Inhibits proliferation of NCI-H2122 cells
- Achieves complete tumor regression in xenograft models with single-agent oral administration
- Rapidly absorbed with dose-proportional exposures
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Apexbio Technology LLC Pan-RAS-IN-1 1835283-94-7 1mL(10 mM in DMSO)
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Pan-RAS-IN-1 (CAS 1835283-94-7) is a small-molecule inhibitor targeting the RAS family of GTPases including KRAS HRAS and NRAS It acts by disrupting the interaction between RAS proteins and their downstream effectors thereby inhibiting RAS-mediated signaling pathways responsible for regulating cell proliferation and oncogenic transformation Pan-RAS-IN-1 is suitable for investigating the functional roles of RAS-dependent signaling in various cellular contexts and is a valuable tool for studies focused on RAS-driven tumorigenesis and the development of targeted therapeutic strategies
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Medchemexpress LLC 4-nitro-1-(triphenylmethyl)-1H-imidazole | 173865-33-3 | 98.0% | 355.39 g/mol | C22H17N3O2 | 1 ML
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CDD3505 is a small-molecule research compound (4-nitro-1-(triphenylmethyl)-1H-imidazole) reported to elevate high-density lipoprotein (HDL) cholesterol by inducing hepatic cytochrome P450 3A (CYP3A) activity. It is used as a tool compound in studies of lipid metabolism and drug-enzyme interactions and is supplied in solution and solid forms for in vitro research under appropriate safety conditions.
- Induces hepatic CYP3A enzymes and elevates HDL cholesterol.
- Suitable for in vitro studies of lipid metabolism and drug metabolism.
- Supplied as 10 mM solution in DMSO and as solid quantities for formulation flexibility.
- Typical purity ≥98.0%.
- CAS number 173865-33-3; molecular weight 355.39 g/mol.
- Handle according to SDS and use appropriate laboratory safety practices.
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Medchemexpress LLC MBL1 Rat HEK293 F 5ug | 5ug
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MBL1 protein is a calcium-dependent lectin that participates in innate immunity by binding to mannose fucose and N-acetylglucosamine on microorganisms and activating the lectin complement pathway MBL1 Protein Rat (HEK293 Fc) is the recombinant rat-derived MBL1 protein expressed by HEK293 with C-hFc labeled tag
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Medchemexpress LLC (E)-JP-2-196 TFA | 3065021-33-9 | 97.9% | 388.34 | C17H19F3N2O5 | 50mg
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JP-2-196 (TFA) is a molecular glue handle that can bind to the E3-ubiquitin ligases (RNF126 LRSAM1 RNF40 MID2 and RNF14) in vitro JP-2-196 (TFA) can be used to synthesize molecular glue degraders[1]
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![Medchemexpress LLC 3-bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6-(methylcarbamoyl)phenyl]pyrazole-5-carboxamid | 736994-63-1 | MFCD28053506 | 99.4% | 473.71 g/mol | C19H14BrClN6O2 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000264479.png-250.jpg)
Medchemexpress LLC 3-bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6-(methylcarbamoyl)phenyl]pyrazole-5-carboxamid | 736994-63-1 | MFCD28053506 | 99.4% | 473.71 g/mol | C19H14BrClN6O2 | 5 MG
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Cyantraniliprole is the analytical standard of the insecticidal active ingredient cyantraniliprole, provided as a research-grade reference material for analytical testing and method development. The compound acts as a ryanodine receptor agonist with insecticidal and antioxidant activity, and is supplied in small quantities for laboratory use.
- Purity 99.4%
- Molecular formula C19H14BrClN6O2
- Molecular weight 473.71 g/mol
- Intended for research and analytical applications
- Available in small quantities suitable for analytical standards
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