Pyridines and derivatives
- (4)
- (1)
- (5)
- (5)
- (520)
- (22)
- (2,105)
- (22)
- (2)
- (5)
- (5)
- (271)
- (175)
- (1)
- (14)
- (50)
- (300)
- (86)
- (225)
- (6)
- (4)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (5)
- (1)
- (12)
- (4)
- (8)
- (7)
- (12)
- (60)
- (867)
- (5)
- (55)
- (60)
- (58)
- (19)
- (346)
- (2)
- (4)
- (2)
- (1)
- (1)
- (5)
- (275)
- (1)
- (1,700)
- (2)
- (27)
- (7)
- (1)
- (92)
- (4)
- (13)
- (77)
- (128)
- (54)
- (59)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (5)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (9)
- (4)
- (1)
- (2)
- (4)
- (2)
- (1)
- (5)
- (17)
- (23)
- (1)
- (1)
- (60)
- (21)
- (1)
- (1)
- (29)
- (49)
- (7)
- (2)
- (1)
- (5)
- (6)
- (12)
- (1)
- (1)
- (1)
- (18)
- (1)
- (14)
- (4)
- (1)
- (11)
- (5)
- (1)
- (10)
- (15)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (9)
- (7)
- (1)
- (2)
- (1)
- (4)
- (6)
- (2)
- (1)
- (1)
- (1)
- (4)
- (4)
- (1)
- (1)
- (5)
- (15)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (12)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (15)
- (17)
- (4)
- (2)
- (2)
- (5)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (7)
- (5)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (16)
- (7)
- (5)
- (1)
- (1)
- (3)
- (5)
- (10)
- (2)
- (1)
- (6)
- (6)
- (7)
- (12)
- (1)
- (1)
- (39)
- (1)
- (12)
- (11)
- (4)
- (2)
- (2)
- (15)
- (15)
- (1)
- (1)
- (1)
- (2)
- (9)
- (3)
- (2)
- (1)
- (1)
- (3)
- (6)
- (3)
- (3)
- (1)
- (3)
- (1)
- (1)
- (1)
- (3)
- (3)
- (1)
- (6)
- (5)
- (2)
- (1)
- (19)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (22)
- (22)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (22)
- (16)
- (6)
- (2)
- (1)
- (1)
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- (48)
- (1)
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- (9)
- (22)
- (30)
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- (7)
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- (1)
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- (26)
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- (1)
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- (72)
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- (1,561)
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- (237)
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Filtered Search Results
Medchemexpress LLC CH 275 | 174688-78-9 | 99.6% | 1485.77 | 1 MG
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CH 275 is a peptide analog of somatostatin that preferentially binds to somatostatin receptor 1 (sst1) with a Ki of 52 nM. It acts as a potent and selective sst1 agonist. This compound can be utilized for research related to Alzheimer's disease.
- Potent and selective sst1 agonist (IC50=30.9 nM)
- Binds to somatostatin receptor 1 (sst1)
- Activates neprilysin activity in vitro
- Decreases neprilysin/SRIF levels in App knock-in mice in vivo
- Increases neprilysin expression and reduces Aβ plaque load in hippocampus in vivo
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Ropitoin (TR 2985) | 56079-81-3 | 483.60 | 20 MG
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Ropitoin (TR 2985) is a novel antiarrhythmic agent.
- Purity: 98.2%
- Molecular weight: 483.60
- Chemical formula: C₃₀H₃₃N₃O₃
- CAS number: 56079-81-3
- Appearance: Solid
- Color: Off-white to light yellow
- Shipping: Room temperature in continental US; may vary elsewhere.
- Storage (powder): -20°C for 3 years, 4°C for 2 years.
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month.
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Medchemexpress LLC Indacrinone | 56049-88-8 | 365.21 | 5 MG
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Indacrinone (MK196) is an investigational diuretic that exhibits pronounced saluretic activity in rats and dogs, and both uricosuric and saluretic activity in chimpanzees. It is intended for research use only.
- Investigational diuretic for research
- Displays strong saluretic and uricosuric activity
- Powder stable for 3 years at -20°C
- Solution stable for 6 months at -80°C or 1 month at -20°C
- Highly soluble in DMSO
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Medchemexpress LLC Etodolac | 41340-25-4 | MFCD00133313 | 99.48% | C17H21NO3 | 50 MG
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Etodolac | 41340-25-4 | MFCD00133313 | 99.48% | C17H21NO3 | 50 MG
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Medchemexpress LLC Abametapir | 1762-34-1 | 184.24 | 5 G
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Abametapir is a metalloproteinase (MMP) inhibitor that targets metalloproteinases crucial for egg hatching and louse development. It can inhibit the hatching of both head and body lice.
- Targets metalloproteinases
- Inhibits egg hatching in lice
- Effective against head and body lice
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Medchemexpress LLC N-[5-(furan-2-yl)-1,3,4-oxadiazol-2-yl]-2-phenylquinoline-4-carboxamide | 851095-32-4 | 98.4% | 382.37 g/mol | C22H14N4O3 | 25 MG
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STX-0119 is a small-molecule inhibitor that selectively blocks STAT3 dimerization and suppresses STAT3-dependent transcription (reported IC50 ≈ 74 μM). It is provided for research use and is supplied as a solid for biochemical and cellular studies.
- Selective STAT3 dimerization inhibitor.
- Inhibits STAT3 transcription with IC50 ≈ 74 μM.
- Molecular formula C22H14N4O3; molecular weight 382.37 g/mol.
- High purity (98.4%) and white to light yellow solid appearance.
- Soluble in DMSO (13.33 mg/mL; may require warming and sonication).
- Store at 4°C protected from light; in solution store at -80°C (up to 6 months) or -20°C (up to 1 month).
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Cayman Chemical 5cis Iloprost Prostaglandins
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5-cis Iloprost is the C-5 cis-isomer of iloprost, a second generation structural analog of PGI2 (prostacyclin). Iloprost displays ten-fold greater potency than the first generation stable prostacyclin analogs, typified by carbaprostacyclin.{3347} There are no published studies of the pharmacological properties of 5-cis iloprost.
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Apexbio Technology LLC Candesartan 139481-59-7 10mM (in 1mL DMSO)
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Candesartan (CAS 139481-59-7) is a small-molecule antagonist targeting the angiotensin II type 1 (AT ) receptor It is designed to selectively inhibit AT receptor-mediated vasoconstriction thereby regulating systemic vascular resistance and blood pressure Candesartan exerts its biological activity primarily through competitive antagonism of the AT receptor In in vitro studies candesartan demonstrates potent inhibition with IC values of approximately 1 12 nM in bovine adrenal cortex tissues and 2 86 nM in isolated rabbit aorta preparations Based on these pharmacological properties candesartan holds research potential in studies of cardiovascular physiology hypertension mechanisms and related therapeutic interventions
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Medchemexpress LLC Macrophage-activating lipopeptide 2 TFA | 99.8% | 2135.56 | 1 MG
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Macrophage-activating lipopeptide 2 TFA is an agonist of Toll-like receptors TLR-2/TLR-6. It enhances endothelial nitric oxide synthase (eNOS) phosphorylation and endothelial cell release of NO, which improves vasodilation. It also enhances endothelial adhesion of white blood cells and improves perfusion recovery and collateral growth in the hind limbs of hypercholesterolemic Apoe deficient mice undergoing experimental femoral artery ligation (FAL).
- Promotes expression of major endothelial adhesion molecules
- Enhances leukocyte endothelial adhesion
- Promotes phosphorylation of protein kinase B and eNOS in endothelial MyEnd cells
- Improves hind limb perfusion recovery and collateral growth
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Medchemexpress LLC SW-100 100mg | 2126744-35-0 | 316.78 g·mol⁻¹ | C17H17ClN2O2 | 100 MG
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SW-100 is a selective histone deacetylase 6 (HDAC6) inhibitor for research use, reported with an IC50 of 2.3 nM. It displays at least 1,000-fold selectivity versus other HDAC isozymes and has improved blood-brain barrier penetration, supporting its use in neurological disease studies.
- Potent HDAC6 inhibition with IC50 of 2.3 nM.
- At least 1,000-fold selectivity versus other HDAC isozymes.
- High purity suitable for research applications.
- Available in common laboratory pack sizes, including 100 mg.
- Soluble in DMSO for solution preparation and storage.
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Medchemexpress LLC Acetamide, 2-[[2-(5-bromo-2-furanyl)-4-oxo-4H-1-benzopyran-3-yl]oxy]- | 819827-50-4 | 98.0% | 364.15 | 10 MG
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CB7993113 is a potent AHR antagonist that directly binds AHR protein and blocks AHR nuclear translocation, inhibiting PAH- and TCDD-induced reporter activity. It shows no toxicity in various human cells and effectively reduces the invasive phenotype of breast cancer cells in vitro.
- Potent AHR antagonist with an IC50 of 0.33 μM.
- Directly binds AHR protein.
- Blocks AHR nuclear translocation.
- Inhibits polycyclic aromatic hydrocarbon (PAH)- and TCDD-induced reporter activity by 75% and 90% respectively.
- Exhibits no toxicity in several human cell types up to 20 μM.
- Significantly reduces the invasive phenotype of breast cancer cells in vitro.
- Effectively blocks acute, 50 mg/kg DMBA-induced hepatic CYP1A1 induction and bone marrow toxicity in vivo.
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Medchemexpress LLC Cefotaxime sodium | 64485-93-4 | 99.1% | C16H16N5NaO7S2 | 1 G
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Cefotaxime sodium is a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic. It demonstrates broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria.
- Beta-lactamase stable cephalosporin
- Third-generation cephalosporin antibiotic
- Broad-spectrum antibiotic activity against Gram-positive and Gram-negative bacteria
- Exhibits an MIC of 0.0625 mg/L for V. vulnificus CMCP6
- Effective in clearing V. vulnificus in vivo when combined with ciprofloxacin
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Medchemexpress LLC N- 4-AMINOBENZOYL -L 5MG | 5MG
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N- 4-AMINOBENZOYL -L 5MG | 5MG
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Apexbio Technology LLC Isocorydine 475-67-2 20mg
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Isocorydine (CAS 475-67-2) is an isoquinoline alkaloid originally isolated from Menispermum dauricum Studies have shown that isocorydine in combination with doxorubicin (DOX) exhibits potential in targeting hepatocellular carcinoma (HCC) This compound is utilized in research investigating mechanisms of chemosensitization and exploring novel therapeutic strategies for liver cancer particularly in enhancing the efficacy of conventional chemotherapeutic agents
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Medchemexpress LLC Pentoxyverine | 77-23-6 | 98.9% | 333.47 | C20H31NO3 | 5 MG
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Pentoxyverine is an antitussive and spasmolytic research chemical reported to act as a sigma-1 receptor agonist and muscarinic antagonist. It is supplied as a solid for biochemical and pharmacological studies and is used in receptor-binding and mechanism-of-action investigations.
- High purity suitable for analytical and pharmacological studies.
- Supplied as a solid in small milligram quantities.
- Useful for receptor binding and antitussive mechanism research.
- Molecular formula C20H31NO3 and molecular weight 333.47.
- CAS number 77-23-6 for unambiguous identification.
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